PHARMACEUTICAL PRODUCTION TECHNOLOGIES

Filling gelatin capsules with powders and granules

8343

8522406

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Technologies and equipment for ointment production

8404

8523015

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The process of making ointments can be periodic or continuous. The periodic process can be one-, two-, three-stage, etc., depending on the number of devices in which separate stages of the process of obtaining ointments are consistently carried out. The technology of manufacturing ointments at pharmaceutical enterprises is carried out in accordance with the regulations. It includes the following stages: sanitary treatment of premises and equipment; preparation of raw materials (medicinal substances, ointment base, packaging containers, etc.); introduction of medicinal substances into the base; homogenization of ointments; standardization; packing and storage of ointments. Sanitary treatment of premises and equipment is aimed at preventing microbial contamination during the production, storage and transportation of ointments, at creating safe working conditions and protecting the health of workers.

Ointments, requirements for ointments and their classification

8404

8523024

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Standardization of ointments in production

8397

8522951

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Intra-shop control of ointments is carried out at almost every stage of production and especially before packing the drug. The final conclusion on all indicators of the quality of finished products is given by the quality control department of the plant. In the conditions of industrial production, the test is carried out in accordance with the requirements of the general article of the State Pharmacopoeia (GF) for ointments, as well as the requirements included in the articles of the GF for individual names of ointments. The ointment is standardized in appearance, uniformity, content of medicinal substances, pH value, degree of dispersion of solid particles, colloidal stability and thermal stability. The company controls the appearance, smell and characteristic organoleptic properties (if any) of ointments and other soft medicines. They should not have a rancid smell, as well as (if there are no other indications in private articles) signs of physical instability (aggregation of particles, coalescence, coagulation and stratification). The amount of medicinal substances in ointments is determined by the methods given in private pharmacopoeia articles for the tested ointment. Standar...

Leukoplasty production process

8439

8523371

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Methods of industrial production of gelatin capsules

8333

8522305

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Industrial production of plasters

8439

8523374

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Granulation and fluidized bed drying

8485

8523827

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Spray drying method (physicochemical microencapsulation method)

8511

8524093

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Microspheres and pellets technology basics

8479

8523774

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