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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Archive by Category "PHARMACEUTICAL PELLET MICROSPHERES"

PHARMACEUTICAL PELLET MICROSPHERES

Technologies of pellet production and equipment used

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  • Production of high-quality pellets
  • Build-up on microcapsules
  • Pellets production
  • Microcapsule buildup
  • Packing of gel in aluminum tubes
  • Mixing powder with water
  • hard and soft dosage forms pharmacology
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  • equipment for preparing and mixing powders
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  • Flowpack

Pellets (microspheres) are obtained in several ways: direct pelletizing, pelletizing by rolling, pelletizing in a fluidized bed, pelletizing by layering. Pellets (microspheres) are obtained in several ways: direct pelletizing, pelletizing by rolling, pelletizing in a fluidized bed, pelletizing by layering. Direct pelletizing involves the creation of pellets directly from a powder with a binder or solvent. This is a fairly fast process that requires a small amount of excipients. In the initial stage, the powder is mixed and moistened. Then, if necessary, a solvent or binder is added, which are sprayed onto the powder particles. The powder layer is driven in a circular motion. As a result of the collisions and accelerations that occur in this case, agglomerates arise, which are rolled to obtain dense…

Pelletizing in pharmaceutical production

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  • pharmaceutical pellets
  • production of pellets
  • pelletizing
  • pharmaceutical pellets
  • Pressing on a tablet machine
  • Packaging bottles wholesale
  • flow reactor
  • hydrophilic base
  • sulfuric acid into water or water into acid
  • range of forms
  • exhibition analytics
  • Capping of medication vials
To study the formation of pellets (microspheres), it is necessary to understand the mechanisms of formation and growth of granules. Some theories were derived from experimental data, others were derived from visual observations. Conventional granulation as the most fully studied and classified process of formation of microspheres, carried out using different equipment, was divided into three successive stages: the stage of core formation, the transitional stage and the stage of sphere growth. However, based on experiments to study the mechanism of formation and growth of microspheres, the following mechanisms of microspheres growth have been proposed: core formation, joining, layering and transfer of material by friction.

Pelletizing by layering

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  • Pellets
  • Microspheres and pellets fundamentals of technology
  • Pellets
  • Tablets in a pink shell
  • Semi-automatic Filling machine
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  • packaging of tablets technologist recommendations when purchasing
  • Corking of vials
Microspheres can also be made by layering a medicinal substance on inert microspheres. The layering process is a sequential application of layers of a medicinal substance from a solution, suspension or dry powder to the nuclei. The nuclei can be crystals or granules of the same material or inert particles. When layered from a solution or suspension, the particles of the medicinal substance are dissolved or suspended in a liquid. When the powder is layered, complete dissolution does not occur due to the small amount of liquid, regardless of the solubility of the active component in the liquid. When powder coating of the drug, the binder solution is first sprayed onto the inert nuclei, and then the powder is applied. By adding a layer-forming component,...

Microspheres and pellets technology basics

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  • Production of pellets
  • Pellets pharmaceutical production
  • Gelatin capsules in a blister pack
  • Pharmaceutical pellet microspheres
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Microspheres (pellets) are a new type of solid dosage form. Recently, in the pharmaceutical industry, drug manufacturers have been producing microspheres, or pellets (from the English pellet — ball, pellet, pellet), as the final or intermediate type of dosage form for the production of finished dosage forms. Microspheres are increasingly being used in the production of finished medicines, as they have a number of significant and undeniable advantages. Pellets can be tableted with the addition of suitable excipients, they can be the contents of capsules, as well as be part of suspensions. Microspheres (pellets) are agglomerates of fine powders or granules, which, in turn, may consist of medicinal and auxiliary substances. Microspheres are small, spherical or hemispherical solid particles with a diameter of 0.5 to...
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