TABLET MANUFACTURING TECHNOLOGY

Tablets as a dosage form

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Tablet (from Lat. tabella — tablet, tile) is a dosed dosage form obtained by pressing medicinal or a mixture of medicinal and auxiliary substances. Intended for internal, sublingual, implantation or parenteral use. The first information about tablets dates back to the middle of the XIX century. In Russia, the first large tablet workshop opened in 1895 in St. Petersburg. Tablets are one of the most common and promising dosage forms and, as mentioned earlier, currently account for about 80% of the total volume of finished dosage forms. This is due to the fact that tablets have a number of advantages over other dosage forms, namely: the accuracy of dosing of medecine injected into tablets; the portability of tablets, which provides convenience of dispensing, storage and transportation of the dosage form; the safety of medecine in a compressed state. For insufficiently resistant substances, it is possible to apply protective shells; masking of unpleasant organoleptic properties of medicinal substances (taste, smell, coloring ability), which is achieved by applying shells of sugar, cocoa, chocolate, etc.; localization of the action of the medicinal substance in a certain place of the ga...

Stages of preparation of raw materials for tablet production

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Force to push tablets out of the matrix

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Basic requirements for tablets

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Correcting agents, dyes

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Antifriction agents in pharmaceutical production

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