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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Methods of industrial production of gelatin capsules

Methods of industrial production of gelatin capsules

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Methods of industrial production of gelatin capsules

Methods of industrial production of gelatin capsules

There are three main methods of industrial production of gelatin capsules: the dipping method, the rotary-matrix method and the drip method.
It should be noted that for the production of hard capsules, the dipping method has found widespread use in industry, being essentially the only one. However, to obtain soft gelatin capsules (with drip sealing), the method is currently used only in laboratory conditions, as it is low-performance and labor-intensive.
The stamping method, or rotary matrix method, is used for the production of soft gelatin capsules and is the most rational for their production in the conditions of industrial production. The principle of the method is to first obtain a gelatin ribbon, from which capsules are stamped on rolls immediately after filling and sealing.

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  • Information updated : 09 / 07 / 2024
  • In stock
  • Manufacturer : 1 year for Methods of industrial production of gelatin capsules

Model: Capsule production gelatin capsules

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The TS-SG10 produces two gelatin ribbons that are brought together on the format drums. The dispenser is lowered and dispenses several doses of drug directly into the capsule formation site at the same time. In the fifth stage, the finished capsules are fed into a drum dryer docked with the TS-SG10 machine. In the dryer, capsule processing, which includes removing oil from the capsule surface and drying, takes place in stages. The drum makes a set number of clockwise revolutions. The drum then stops and makes a few revolutions in the opposite direction. The capsules fall into the next drum. At the same time, new capsules are fed into the first drum. The procedure is repeated in each subsequent drum. From the last drum, the finished capsules are discharged into a tray. At the last, sixth stage of production of soft gelatin capsules, trays with capsules are installed in racks and transported to a special room equipped with a clean air supply system and climate control system: the room maintains a constant temperature of 20-22 ° C and relative humidity from 20 to 22%.

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Technical specifications

Automats using this method perform all operations with high accuracy (±3%) and high productivity (from 3,000 to 76,000 capsules per hour), and can produce capsules of different shapes, a wide range of capacities and fillings of different consistencies (mainly liquid and paste).
Ki’s Corporation, a South Korean company, manufactures a set of process equipment for manufacturing and filling soft gelatin capsules. The production process of gelatin capsules can be divided into six main stages. The first stage of production is the preparation of the drug at a temperature of 60-70 ° C in a vacuum mixer or tank. The tank has a volume of 200 liters and is equipped with an integrated temperature control sensor. (#The second stage of production, which is carried out in parallel with the first, is the preparation of gelatin mass in one of the gelatin melting tanks, working alternately).

Additional information

Gelatin, supplied as granules, is melted at a temperature of 90-100 °C in a 400 l tank equipped with a stirrer with a fixed rotation speed of 40 rpm. For transportation of the finished gelatin mass is used auxiliary tank for gelatin It has a volume of 2000 liters, and is equipped with an integrated temperature control sensor. In the tank, the product temperature is maintained between 70 and 90 °C.
The third stage of production is to prepare the machine for the manufacture and filling of soft gelatin capsules model TS-SG10. Prepared gelatin and drug are loaded into the machine. After that, the machine is set up and the capsules are produced. The fourth stage is the actual production of soft gelatin capsules.

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