The modern V-shaped mixer is a powder mixer with an internal rotating shaft with lobes for mixing dry powder material in pharmaceutical, food, chemical and other industries. The useful volume is 180 liters. Effective mixing of powders without stagnant zones. Made of stainless steel according to GMP requirements. Thanks to the unique design, uniform mixing…
There are three main methods of industrial production of gelatin capsules: immersion method, rotary matrix and drip. It should be noted that for the production of solid capsules, the dipping method has found wide application in industry, being essentially the only one. However, to obtain soft gelatin capsules (with drip sealing), the method is currently...
The reproduction and accuracy of dosing depends on the characteristics of the filler, the filling method and the type of filling machine. Active substances for filling into solid gelatin capsules must meet the following requirements: the contents must be released from the capsule, providing high bioavailability; when using automatic filling machines, active substances must have...
Highly efficient mixer for mixing dry powder material in pharmaceutical, food, chemical and other industries. Thanks to the unique design, uniform mixing occurs. The useful volume is 50 liters. The mixing tank is made of stainless steel with polished inner and outer walls. Performed according to GMP. We provide detailed instructions for setting up the…
In modern pharmaceutical production, the following methods of applying film coatings are used.Coating in drums; coating in a fluidized bed (spraying from above, spraying from below, coating tangentially); technology of jet fluidization. Coating in drums has already been discussed in the section "Methods and equipment for coating".The technological parameters of the film coating process are:...
After the tableting process, the finished tablet most often needs to be coated. In the modern pharmaceutical industry, the importance of tablet coating is increasing.
The application of film coatings is carried out in apparatuses for combined granulation, drying and coating processes. A distinctive feature is the lower location of the nozzle. There are two possible ways of organizing the process: applying a film coating directly to crystals or granules containing a medicinal substance; conducting a preliminary stage — layering...
Equipment for assembling, cutting and laying adhesive plaster (Leucoplastrum), or elastic external adhesive plaster (Emplastrum adhaesivum elasticum externum). It is possible that the assembly, cutting and capping of a small and medium-sized adhesive plaster is carried out on an automated EURO type in the Italian company EURVSICMA. Depending on the material and size of the...
Microspheres (pellets) are a new type of solid dosage form. Recently, in the pharmaceutical industry, drug manufacturers have been producing microspheres, or pellets (from the English pellet — ball, pellet, pellet), as the final or intermediate type of dosage form for the production of finished dosage forms. Microspheres are increasingly being used in the production...
The granulate is obtained in the process of granulation of wet mass on special granulator machines. The principle of operation of granulators is that the material is wiped with blades, springy wolves or other devices through a perforated cylinder or mesh. To ensure the wiping process, the machine must operate at an optimal mode without...
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