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The filtration system ensures that fine particles are fully returned to the process and no product separation into fractions occurs. This design allows efficient coating of pellets, microparticles, tablets of different shapes, sizes and densities and allows the granulation process to be carried out in large production batches. Tangential coating is optimally suited for the creation of shells with a high solids content and is carried out on the machine. It is driven in a spiral direction by a rotating gas distribution grate, from the edges of which the supplied air is directed into the product layer. A spray nozzle is arranged tangentially with respect to the rotor insert and atomizes the liquid into the product layer in the same direction. Using the rotor method, a very thick film layer can be applied. This method is also suitable for producing pellets by direct pelletizing in a fluidized bed. Coating by jet fluidization technology is used for tablets and pellets that are difficult to fluidize. Fluidizing jet technology makes it possible to coat extremely fine, coarse and polydisperse products. In contrast to conventional fluidized bed processes, the air enters the working chamber through a longitudinal slit instead of a gas distribution grate. As a result of the two-stage expansion of the bed (in the working chamber and above the working chamber), the process air velocity drops drastically. As a consequence, no fine particles are transported out of the process, which makes it possible to fluidize even finely dispersed products. It is also possible to fluidize coarse and polydisperse products, as the flow velocity in the center of the fluidization chamber is high. A stable fluidized bed is also possible with sticky and lumpy products. The speed of the product can be adjusted as it is transported in a directional manner: upwards in the middle and downwards on the sides. The central nozzles spray at the place of the highest product speed and the highest energy flow. Due to the high product velocity at the nozzle there is no agglomeration of particles. High atomization performance is also possible with small amounts of product in the spraying chamber. At the same output, the average processing time with this technology is reduced compared to conventional fluidized bed technology. Coating is an important process step in the manufacture of solid dosage forms. The challenge for many pharmaceutical companies is to develop and search for new properties of coating agents and to apply innovative coating technologies and equipment.
Pharmaceutical Glossary
Technical specifications
In fluidized bed coating, the pellets and pellets are “liquefied”, the coating fluid is sprayed on them and the product is dried. The small droplet size and low viscosity of the atomizing medium ensure uniform application of the product.
Overhead spray coating is used for a wide range of coatings, from general purpose coatings to gastric juice soluble coatings. In overhead spray coating in fluidized bed (in batch and continuous systems), the particles are “liquefied” in a stream of heated air, which flows through a gas distribution grid into the product container. The coating fluid is injected into the fluidized bed through a nozzle in the opposite direction to the air flow (countercurrent, from top to bottom). With further upward movement of the particles in the air flow, drying takes place. To carry out the coating process, two types of fluidized bed systems are used: batch and continuous. These plants can also be used for the granulation process (see section 4.8). %. Glatt batch fluidized bed plant. The conical shape of the zone where the gas flow velocity is reduced allows even very fine products to be processed. Different variants of the gas distribution grids ensure an optimum gas flow over the product.
Glatt continuous fluidized bed coater. The coating method is particularly suitable for the creation of protective and colored coatings under the condition of high process throughput.
The product is continuously fed from one side of the plant and transported upwards by the air flow over the gas distribution grid. The plant is divided into different zones for different purposes: preheating, spraying and drying. The dry coated tablets are continuously removed from the plant.
Spray coating from below in a batch fluidized bed plant using the HS Wurster Glatt nozzle is particularly suitable for the production of pellets and pellets with controlled release of bioactive substances. When conducting the coating process with the HS Wurster nozzle, complete coverage of the particle surface can be achieved with a small amount of coating agent. The atomizing nozzle is installed in the gas distribution grille so that the atomizing agent moves in the same direction as the air flow. By using the Wurster HS nozzle and a gas distribution grid with different types of perforations, the coated particles are accelerated inside the nozzle and flow uniformly through the atomizing cone.
Additional information
In a further upward motion, the particles dry out and descend again outside the HS Wurster nozzle to the gas distribution grid. There they are again directed towards the inside of the nozzle, where they are again accelerated by the atomizing liquid jet, thus forming very homogeneous films. As a result, particles of different sizes have a uniform film coating. Spray coating from below in a continuous fluidized bed system developed by Glatt is particularly suitable for the creation of protective and colored coatings under the condition of a high production rate. The product is continuously fed from one side of the plant and transported by the air flow upwards above the gas distribution grid. The plant is divided into different zones: preheating zone, atomization zone and drying zone, with atomization from below. Dry pellets and coated pellets are continuously removed from the plant. Spray coating from below in a fluidized bed system developed by Hiittlin. Thanks to Hiittlin’s Turbojet and Diskjet gas distribution units, the product flows in a defined direction throughout the entire container volume as well as in the spray area. Due to the defined geometry of the units, the air flow can be precisely controlled. Homogeneous product movement and mixing is achieved. Due to the 45° angle of air flow, the strain on the filters is reduced. There are no stagnant zones in the product container.
In fluidized bed apparatuses for coating, the nozzles that atomize the coating agents are of great importance. The nozzle has a third component called microclimate, which is what distinguishes it from the one used in conventional technology. The microclimate keeps the nozzle clean of solution and product. Thus, the distribution and droplet size remain constant and are reproducible. The nozzle is freely accessible during operation, so there is no need to interrupt the process in case of nozzle clogging. Solution losses are reduced due to the appropriate nozzle positioning. INN O JET has developed the AirCoater coating machine, which allows the coating to be applied with a high degree of efficiency. The special feature of this unit is the INNOJET Orbiter gas distribution unit of a somewhat unusual design. The flow of process air passes through the holes of the gas distribution unit, which is a ring of different diameters, assembled in a single structure with gaps between them. This assembly design ensures efficient, gentle and reproducible product flow. Application of the atomized liquid is carried out by a spray nozzle, which can be used to control the droplet size. Atomization takes place at 360°, which allows an even application of the coatings.
Order status tracking
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Brussels, then I want to buy an automatic capsule machine model GN-28 02/05/2024 00:01
Good afternoon, Alexander! On the first question - the shipment will arrive in Brussels between 12:00-14:00. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 02/05/2024 00:03
Good afternoon, I am hoping closer to evening to get the UNIC 600A Tablet Press in Sigisoara ! Please comment. 02/05/2024 00:11
Good day, Benjamin! Our manager has communicated with the delivery service, the equipment will be delivered to Sigisoara at your address. Please let us know when you receive it. 02/05/2024 00:12
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 02/05/2024 00:21
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Layla, this chat is only for tracking shipments. 02/05/2024 00:25
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Kansas City. Please confirm the delivery time. 02/05/2024 00:31
Good afternoon Emily, your shipment has left. Arrival time tomorrow until 16:30. The driver will call you back later. Please organize prompt unloading. 02/05/2024 00:33
Good day, delivery time of semi-automatic drum filling machine DF-10 to Vichy, will the courier call us? 02/05/2024 00:41
Lila, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 02/05/2024 00:43
To what address to send you samples of bottles and caps to send them to the factory ? Regards Maya. 02/05/2024 00:51
Good day, Maya We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 02/05/2024 00:55
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 02/05/2024 01:01
Oliver, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 02/05/2024 01:05
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 02/05/2024 01:11
Hello Mason, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in Athens to 50 working ( not calendar) days. Action taken. 02/05/2024 01:14
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Colorado Springs. Please confirm the delivery time. 02/05/2024 01:21
Good afternoon David, your shipment has left. Arrival time in the interval from 14:00-16:00. The driver will call you back later. Please organize prompt unloading. 02/05/2024 01:25
Rotary tablet press RZK-25 I want to order with delivery to Berlin 02/05/2024 01:31
Good day, Skylar We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 02/05/2024 01:34
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER