MEDICINE MANUFACTURING FROM EXPERTS

How to organize the production of pellets?

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About granulation. By themselves, dry powder particles do not form into granules. The powder should be moistened with a liquid with a binder added to it. It can be powdered sugar, an aqueous solution of gelatin and a bunch of other substances that ensures the gluing of particles together. That is, you need to take a powder and some liquid with a bonding agent. Then you need to gradually inject this liquid into the powder through the sprayer, while stirring. Then the moistened mass needs to be granulated.

How to organize filling into cellular packaging?

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1. The critical part. The text was logical only to the point where the required productivity of 150,000 pieces per month is indicated. You will probably be surprised, but if you take 25 working days, then it’s only 6000 pieces per day. And if we assume an 8-hour working day, then you only need to pour 750 bottles per hour. What lines of automatic lines are you talking about??? The more or less automatic line is from 2000 vials per hour. You won’t have anything to download it with. And pay a lot of money to turn on the line for 8 hours a month. With your volumes, one grandmother will be enough, who will use semi-automatic desktop machines especially slowly. By the way, the…

How to develop a process for encapsulating powders?

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You want to encapsulate the powder into solid gelatin capsules. I want to share with you some information that may help to reconsider the need to purchase some types of equipment from your list. Usually there are powders that are good and bad loose. To fill solid gelatin capsules with such powders, there are two types of equipment: 1. What I advise you to use (excellent machines with low performance). 2. Automatic capsule filling machines of high performance. I am sending you their fundamental difference in the text of the letter at the end.

How to organize the production of gelatin capsules?

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1. This equipment is attractive only because it is available in USA and there is no need to wait for it. 2. The cost is much lower than now you will buy new equipment. 3. If desired, you can invite (for money) specialists from the factory and set up everything in USA, you can order spare matrices without problems in any other factory.

How to organize the batching of powder?

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On machines for boilies. I recommend you this model for balls of 5 and 10 mm. The cost, taking into account the replacement equipment, is 6000 USD, the price includes delivery to the door. For balls with a diameter of 15.20 and 25 mm, you need to take separate machines. It does not work to make replaceable shafts. The cost of each car is 3000 USD The price includes delivery to the door.

How to organize the packing of powder into bags?

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Mixing the powder. You need to understand exactly what type of powder mixer you need. I see that you have a 5% corn syrup supplement. Syrup, as I understand it, in liquid form. This creates a big problem with high-quality mixing with dry powder, and later with its packing into bags.

How to choose equipment for pharmaceutical production?

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1. Buy equipment one by one. The first one came, the next one was paid for. Thus, you will be able to check the supplier and the quality of the equipment itself. 2. Choose the equipment not in a list, but with a mandatory discussion of the details of the operation of each equipment and the properties of your raw materials. One equipment works well with one raw material and one flour with another.

How to organize the production of tablets?

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Choose the press model that suits you in terms of price and performance. That’s enough to get started. You will have a press, you already have powder. Start the pressing process. As problems arise, we will solve them with my help. Any press can make 10-20 tablets.

How to organize powder mixing production?

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A V-shaped mixer, inside of which there is a shaft with petals, which breaks up the powder flows, additionally mixing it. And in general, there are no universal powder mixers that are effective in 100% of cases.

How to develop a process for granulating powders?

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Here are my tips for you. Now the most important thing about the ability of the granulator to make pellets of the quality you need. In fact, a granulator is a simple mechanical device that wipes moistened powder through holes in a mesh or stainless steel sheet. Granulator – Does not mix powder – Does not moisten powder – Does not mix moistened powder – Does not dry granules – Does not divide granules into good and nonconditioning. – Does not give 100% granules of the same shape size, etc. Its simple function is to wipe the powder you moistened through the holes. To check whether the granulator is suitable for you, you can easily and simply (and at the same time practice in humidification…