The application of film coatings is carried out in apparatuses for combined processes of granulation, drying and coating. A distinctive feature is the lower location of the nozzle. Two options for organizing the process are possible: applying a film coating directly to crystals or granules containing a drug substance; carrying out the preliminary stage - layering of the medicinal substance on inert particles (pellets are most often used), after which a film coating is applied ....
Coating in a fluidized bed of fine particles under supercritical conditions is a new emerging technology designed to encapsulate thermolabile products. Supercritical fluids are unique solvents, since their density is similar to the density of liquids, while the viscosity and diffusion coefficient are close to those for gases. Spraying supercritical solutions allows you to get droplets and particles of submicron size, and ...
The production of Uniplast fixative adhesive tape rolls is carried out on an automatic coating line of the English company Coating and Laminating Systems LTD with a productivity of up to 28 m per minute. The line is intended for applying an adhesive layer to the base material (fabric, non-woven fabric, film). It consists of a number of sequentially installed nodes: unwinding node No. 1; coating unit; convection-type drying chamber ...
As with sugar coatings, problems can occur after or during the film coating process. Coated tablets, pellets and granules may not be strong enough or delaminate during the coating process. Due to the fact that the film coatings are relatively thin, their ability to hide defects is much lower than that of the sugar coating. When using a film coating, ...
With this type of coating, the drug substance from the tablets can be released instantly. These types of coatings include polymers developed by BASF: polyvinyl alcohol (PVA), Kollicoat IR white and Kollicoat Protect. PVA-based films are very flexible, but the coating process is possible only in a narrow range of technological parameters. This polymer disperses rapidly in water ...
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