For most chemical and pharmaceutical preparations, the tablet production technology consists of the following separate operations: Weighing the starting material, grinding, sieving, mixing, granulating, tabletting (pressing), coating. Some of these operations in the manufacture of pharmaceuticals may not be available. The most common are three general technological schemes for producing tablets: using wet granulation, dry granulation and direct compression.
A tablet (from Lat. Tabella - a tablet, a tile) is a dosage form obtained by compressing medicinal products or a mixture of medicinal and auxiliary substances. Designed for internal, sublingual, implantation or parenteral use. The first information about tablets dates back to the middle of the 19th century. In Russia, the first large tablet workshop was opened in 1895 in St. Petersburg. Pills are one of the most common ...
The following requirements are made for tablets: dosing accuracy - uniformity (uniformity) of the distribution of the active substance in the tablet, the correct weight of both the tablet itself and the medicinal substances included in its composition; mechanical strength - hardness, brittleness, brittleness - characterize the quality of the tablets; tablets should be strong enough to remain intact under mechanical stress during packaging, transportation and storage; disintegration ...
The German-Swiss company FrymaKoruma, a member of the Romaco group of companies, is well known in the global pharmaceutical equipment market. In Russia, the equipment of this company is also widely represented at many enterprises. In particular, at one of the leading Russian pharmaceutical companies of Akrikhin OJSC, the production of ointments and creams is carried out at the FrymaKoruma Disho installation. Vacuum production plant for liquid and pasty products FrymaKoruma MaxxD, ...
The diphilic bases have a soft consistency and are easily distributed on the surface of the skin and mucous membranes. The diphilic bases are divided into two groups - absorption and emulsion. Absorption bases are hydrophobic. These are anhydrous emulsifier (SAS) hydrophobic compositions with the ability to incorporate the aqueous phase to form an oil-water emulsion system. Most often they contain mixtures of petroleum jelly, ...
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