.. Author Roman Tsibulsky | CATALOG OF PHARMACEUTICAL EQUIPMENT MINIPRESS.RU | MANUFACTURE AND SALE OF

Basic requirements of gmp soft dosage forms

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In the production of ointments, creams and other soft dosage forms, there is a particularly high risk of microbial and other contamination. Therefore, special measures are needed to prevent any contamination. Soft dosage forms have specific rheological properties and in most cases are heterogeneous dispersed systems. Therefore, in order to avoid heterogeneity of the product…

Industrial production of plasters

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Adhesive plasters "Uniplast fixing", "Bactericidal Veropharm" and "Uniplast bactericidal" Modern industrial production of plasters is characterized by a wide range of products. Therefore, it is not possible to consider in detail in one section the production of all types of plasters. In order to understand the specifics of the technological production of plasters, as well...

Hydraulic desktop manual press R-40-1

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Laboratory hydraulic press with a pressing force of 40 tons. The desktop model is used in industry for the production of chemical products, briquettes and tablets in powder metallurgy. Laboratory automatic hydraulic tablet press for the pharmaceutical, chemical and food industries, in powder metallurgy for the production of tablets, briquettes and boluses from bulk powder…

Spray drying

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The vacuum sublimation dehydration method combines the advantages of two well—known dehydration methods - freezing and vacuum drying. During freezing, undesirable changes in the properties of the product are minimal, and during subsequent drying, frozen moisture is removed, which allows the products to be stored in appropriate packaging (for a year or more) at an...

Powder production operations and equipment used

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The technological scheme of powder production includes the following operations: grinding, sieving, mixing (in the manufacture of complex powders), dosing (packing) and packaging. The need to perform certain technological operations depends on the prescription, medical purpose and type of starting preparations. If the starting materials (medicinal and auxiliary substances) do not meet the required fractional…

Polymerization and polycondensation

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When microencapsulating solid particles by polymerization and polycondensation methods, a polymerization initiator is pre-grafted onto the surface of the encapsulated substance.

Preparation of suppository base

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The stage of preparation of the suppository base begins with the weighing of its components. In the first stainless steel reactor with a steam jacket, paraffin is melted, in the second reactor, hydrofluid is melted by supplying steam to the steam jacket. The heated hydrofluid is pumped into a reactor with pre-melted paraffin. The mixture...

Rotary tableting machines

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Rotary tablet machines (RTM), unlike eccentric ones, have a large number of matrices and punches. The matrices are mounted in a rotating matrix table. The pressure in the RTM increases gradually, which ensures a soft and uniform pressing of the tablets. rTMS have high productivity (up to 0.5 million tablets per hour). The technological cycle…

Powder screening in production

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When grinding solid materials on the equipment discussed earlier, a homogeneous product is practically not obtained, Therefore, such an operation as sieving is necessary to separate larger particles. Sieving is an integral part of grinding to obtain a mixture with a certain granulometric composition. Sieving eliminates soft conglomerates of powders by rubbing them through perforated...

Pelletizing by layering

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Microspheres can also be made by layering a medicinal substance on inert microspheres. The layering process is a sequential application of layers of a medicinal substance from a solution, suspension or dry powder to the nuclei. The nuclei can be crystals or granules of the same material or inert particles. When layered from a solution...

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