Video review of the model
Our service and customer service
If, for example, the tablets are ejected with a damaged or uneven surface, this indicates that the mass is strongly adherent or lacks sliding agents, or that the pressing surfaces are not smooth enough. If the tablet has edges, the diameter of the punches used is small. If the tablet surface is bumped, the bottom punch is not raised high enough and its position must be adjusted.
If the tablets disintegrate when ejected, the pressing pressure should be increased or more binders should be added. If the tablets break up, the pressure is too high or the granulate is too dry. The tabletting process may produce tablets with the following defects, such as: Insufficient mechanical strength – observed with insignificant press pressure, insufficient concentration of binder, adhesive and lubricant, and low plasticity of substances. Poor quality coating of tablets. It can be avoided by adding microcrystalline cellulose to the coating, which improves the plasticity of the coating. Adhesion. When the particles of the tablet mass have a higher adhesion to the punch than to each other, adhesion of the particles to the tool occurs. Adhesion at high stock moisture levels to the top punch can cause failure of the apparatus. High stock moisture and insufficient amounts of opening agents also lead to sticking. Excessive rubbing. Excessive kneading of the mass can cause the matrix parts to stick together. Reduction in tablet weight and formation of a non-glossy surface occurs. Reduced shelf life – may occur as a result of the use of inaccurate amounts of loosening, binding, moistening auxiliaries, insufficient pressure, which ultimately leads to incomplete action of the active substance. Inaccurate dosage. If the tablet mass has insufficient flowability, the matrix is filled unevenly. This can be avoided by optimizing the particle size or by adding an excipient such as aerosil. Therefore, to avoid defects in the tabletting process, the optimum parameters should be selected on a case-by-case basis.
Pharmaceutical Glossary
Technical specifications
During the loading operation, the top slider roller with punch is at the highest point of the upper caper (stage I). It then slides down the sloping kapir. The punch touches the matrix hole, plunges into it and compresses the material. The pressure builds up and reaches its maximum at the moment when the slider roller is under the pressure of the roll (pressing operation – stage II). After that, the roller with the punch starts to climb up the capir and reaches the maximum. The lower slider makes the following movements: in the loading stage, its roller is supported by the roller that regulates the volume of the matrix hole. The lower slider moves along the straight capir. During the pressing operation, its roller is lifted by the pressing roller, so that the lower punch exerts pressure on the tablet material from its side. The capir then moves slightly upward, causing the lower punch to push the tablet out (ejection operation – stage III).
After that, due to the lowering of the capir, the lower punch also goes downwards and everything is repeated again. Below is a description of the features of domestic rotary tablet machines. In general, RTMs can have from 12 to 55 dies (positions) in the rotor. Besides, they can be single-flow (with one feeding hopper) and double-flow (with two feeding hoppers). In the latter case, the entire production process is completed in half a rotation of the rotor and, as a result, the productivity of the PTM is dramatically increased. Such a high-performance machine is, in particular, RTM-41, which is a dual-flow machine with 41 pairs of press tools. This machine allows to produce tablets of 5-15 mm and 20 mm diameter. The RTM-300M machine is used to produce cylindrical-shaped tablets of small diameters with flat and spherical ends. Since in RTM the pressure is bilateral and increases (is removed) gradually, tablets are of high quality. These machines work evenly and do not dust. An agitator can be installed in the feed hopper. The rotating rotor allows the installation of devices for powdering the matrix hole before loading, as well as after it (to pollinate the surface of the filled matrix). Some designs have brush wiping or cleaning devices to keep the punches clean. Rotary press-automatic machines are produced, equipped with a vibrating feeder, which can, by adjusting the amplitude and frequency of vibrations of the vibrating, filling part of the feeder, break the forces of adhesion between powder particles, thus significantly increasing its mobility and compensating for the lack of bulkiness.
Additional information
The productivity of automatic machines equipped with a vibrating feeder is increased. In this case, granulation is also required, but with slightly reduced requirements for granulate homogeneity. In domestic tablet presses, the tablet mass and possible mechanical inclusions are controlled during the tabletting process. For mass control there are automatic devices – in case of deviation of tablet mass from the preset one a signal lamp is switched on. Automatic control for metal inclusions is performed with the help of a device that detects and removes tablets with metal inclusions from the’flow. To remove from the surface of tablets coming out of the press, dust fractions are used dedusters. Tablets pass through a rotating perforated drum and are cleaned of dust, which is sucked out of the dedusters by special devices. Tableting of drugs usually occurs at pressures of 25-250 mPa; higher pressures are rarely used. Table 4.8 gives an example of the main technical parameters of rotary tabletting machines. Although RTMs are technically far superior to eccentric machines, they have some disadvantages, namely: complex construction; require more spare punches and dies. The quality of tablets is influenced by the amount of pressure, pressing speed, condition and wear resistance of the press tool, which is subjected to quite a lot of wear and tear, as it experiences heavy loads. The durability of dies is 2-3 times less than that of punches, which is explained by chemical interaction of the matrix material with the tablet mass, rigid loading of the matrix, friction of particles of the pressed material and the tablet against the walls of the matrix;
more difficult preparation for pressing; more labor-intensive cleaning; large variation in mass deviation from the nominal value due to the use of dozens of sets of press tools. Eccentric machines use only one set of press tools and therefore the variation in the mass of individual tablets is less than when pressing on RTM. Based on the above disadvantages it can be concluded that rotary tablet machines are cost-effective only for mass production. Before pressing, any tablet machine must be set up, calibrated and adjusted optimally. Before starting the process, a test tabletting process is carried out by starting the machine manually, which results in the required tablet weight, proper strength and disintegration as well as the elimination of external imperfections.
Order status tracking
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 24/10/2024 02:21
Lily, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 24/10/2024 02:22
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 24/10/2024 02:31
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Maya, this chat is only for tracking shipments. 24/10/2024 02:32
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 24/10/2024 02:41
Aurora, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer as stipulated in the contract. We will report back immediately. 24/10/2024 02:45
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Venice, then I want to buy an automatic capsule machine model GN-28 24/10/2024 02:51
Good afternoon, Zoey! On the first question - the shipment will arrive in Venice between 16:00-18:00. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 24/10/2024 02:52
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 24/10/2024 03:01
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Aiden, this chat is only for tracking shipments. 24/10/2024 03:04
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Braila ? 24/10/2024 03:11
Good afternoon, Scarlett! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 24/10/2024 03:12
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Sofia, then I want to buy an automatic capsule machine model GN-28 24/10/2024 03:21
Good afternoon, Scarlett! On the first question - the shipment will arrive in Sofia after lunch. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 24/10/2024 03:22
Remember me? There's a delivery in the Rotterdam 24/10/2024 03:31
Layla, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be tomorrow until 16:30 in Rotterdam . 24/10/2024 03:31
Good afternoon, I am hoping tomorrow by lunchtime to get the UNIC 600A Tablet Press in Sarajevo ! Please comment. 24/10/2024 03:41
Good day, Emily! Our manager has communicated with the delivery service, the equipment will be delivered to Sarajevo at your address. Please let us know when you receive it. 24/10/2024 03:44
We received our order (BG-150 film coating boiler) in the box there was no spraying nozzle !!! 24/10/2024 03:51
Hello Lily, we checked with the factory. Your nozzle was not received in time for the shipment of the main machine. We will now deliver it to you by DHL express mail. 24/10/2024 03:52
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC CARTONING MACHINES
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION