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Rotary tableting machines

  • Rotary tableting machines
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Rotary tableting machines

Rotary Tableting Machines (RTMs), unlike eccentric machines, have a large number of dies and punches. The dies are mounted in a rotating die table. The pressure in PTMs builds up gradually, which ensures soft and uniform pressing of tablets. PTMs have high productivity (up to 0.5 million tablets per hour).
The technological cycle of tabletting on RTM consists of a number of consecutive operations: Filling of matrices with tabletable material (volumetric dosing method). Pressing itself. Ejection. Dumping of tablets. The operations are performed sequentially in automatic mode. Upper and lower punches slide on guides (capiers) and pass between pressing rollers, which exert simultaneous pressure on them. The pressure increases and decreases gradually, resulting in a uniform and soft pressing of the tablet from the top and bottom. Depending on the type, such machines may be provided with one or two fixed feed hoppers. The feed hoppers may be provided with an agitator. The sequence of movement of one of the dies consists of the following operations:
Loading operation. The lower punch 3 is lowered to a precisely defined position. The upper punch 2 is at this time in the uppermost position as the die opening 7 has come under the funnel /. The loading device of the RTM consists of a hopper hopper and a feeder-doser, fixed on the machine bed.
The hopper provides a continuous flow of the tableting material. For uniform feeding of poorly bulk materials into the feeder hopper funnels can be equipped with agitators, augers, tedders. Feeder-doser is designed to direct and metered supply of tablet mass to the pressing zone. Pressing operation. As soon as the matrix (with filled socket) has passed the funnel together with the rotation of the table top 4, the gradual lowering of the upper punch begins. Having reached the opposite side, it immediately falls under the pressing roller 5. At the same time, the lower punch is pressed by roller 6. Operation of tablet ejection. After passing between the rollers, the upper punch begins to rise. The lower punch also rises slightly and pushes the tablet out of the die. With the help of a knife (scraper) the tablet is thrown off the table top. This motion is performed sequentially by all the press tools (a die and a pair of punches). In order to give the punches proper movement, rollers are attached to the handles (sliders), by means of which they creep (roll) along the upper and lower capiers (guides).

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  • Information updated : 07 / 07 / 2024
  • In stock
  • Manufacturer : 1 year for Rotary tableting machines

Model: Rotary tableting machines

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If, for example, the tablets are ejected with a damaged or uneven surface, this indicates that the mass is strongly adherent or lacks sliding agents, or that the pressing surfaces are not smooth enough. If the tablet has edges, the diameter of the punches used is small. If the tablet surface is bumped, the bottom punch is not raised high enough and its position must be adjusted.
If the tablets disintegrate when ejected, the pressing pressure should be increased or more binders should be added. If the tablets break up, the pressure is too high or the granulate is too dry. The tabletting process may produce tablets with the following defects, such as: Insufficient mechanical strength – observed with insignificant press pressure, insufficient concentration of binder, adhesive and lubricant, and low plasticity of substances. Poor quality coating of tablets. It can be avoided by adding microcrystalline cellulose to the coating, which improves the plasticity of the coating. Adhesion. When the particles of the tablet mass have a higher adhesion to the punch than to each other, adhesion of the particles to the tool occurs. Adhesion at high stock moisture levels to the top punch can cause failure of the apparatus. High stock moisture and insufficient amounts of opening agents also lead to sticking. Excessive rubbing. Excessive kneading of the mass can cause the matrix parts to stick together. Reduction in tablet weight and formation of a non-glossy surface occurs. Reduced shelf life – may occur as a result of the use of inaccurate amounts of loosening, binding, moistening auxiliaries, insufficient pressure, which ultimately leads to incomplete action of the active substance. Inaccurate dosage. If the tablet mass has insufficient flowability, the matrix is filled unevenly. This can be avoided by optimizing the particle size or by adding an excipient such as aerosil. Therefore, to avoid defects in the tabletting process, the optimum parameters should be selected on a case-by-case basis.

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Technical specifications

During the loading operation, the top slider roller with punch is at the highest point of the upper caper (stage I). It then slides down the sloping kapir. The punch touches the matrix hole, plunges into it and compresses the material. The pressure builds up and reaches its maximum at the moment when the slider roller is under the pressure of the roll (pressing operation – stage II). After that, the roller with the punch starts to climb up the capir and reaches the maximum. The lower slider makes the following movements: in the loading stage, its roller is supported by the roller that regulates the volume of the matrix hole. The lower slider moves along the straight capir. During the pressing operation, its roller is lifted by the pressing roller, so that the lower punch exerts pressure on the tablet material from its side. The capir then moves slightly upward, causing the lower punch to push the tablet out (ejection operation – stage III).
After that, due to the lowering of the capir, the lower punch also goes downwards and everything is repeated again. Below is a description of the features of domestic rotary tablet machines. In general, RTMs can have from 12 to 55 dies (positions) in the rotor. Besides, they can be single-flow (with one feeding hopper) and double-flow (with two feeding hoppers). In the latter case, the entire production process is completed in half a rotation of the rotor and, as a result, the productivity of the PTM is dramatically increased. Such a high-performance machine is, in particular, RTM-41, which is a dual-flow machine with 41 pairs of press tools. This machine allows to produce tablets of 5-15 mm and 20 mm diameter. The RTM-300M machine is used to produce cylindrical-shaped tablets of small diameters with flat and spherical ends. Since in RTM the pressure is bilateral and increases (is removed) gradually, tablets are of high quality. These machines work evenly and do not dust. An agitator can be installed in the feed hopper. The rotating rotor allows the installation of devices for powdering the matrix hole before loading, as well as after it (to pollinate the surface of the filled matrix). Some designs have brush wiping or cleaning devices to keep the punches clean. Rotary press-automatic machines are produced, equipped with a vibrating feeder, which can, by adjusting the amplitude and frequency of vibrations of the vibrating, filling part of the feeder, break the forces of adhesion between powder particles, thus significantly increasing its mobility and compensating for the lack of bulkiness.

Additional information

The productivity of automatic machines equipped with a vibrating feeder is increased. In this case, granulation is also required, but with slightly reduced requirements for granulate homogeneity. In domestic tablet presses, the tablet mass and possible mechanical inclusions are controlled during the tabletting process. For mass control there are automatic devices – in case of deviation of tablet mass from the preset one a signal lamp is switched on. Automatic control for metal inclusions is performed with the help of a device that detects and removes tablets with metal inclusions from the’flow. To remove from the surface of tablets coming out of the press, dust fractions are used dedusters. Tablets pass through a rotating perforated drum and are cleaned of dust, which is sucked out of the dedusters by special devices. Tableting of drugs usually occurs at pressures of 25-250 mPa; higher pressures are rarely used. Table 4.8 gives an example of the main technical parameters of rotary tabletting machines. Although RTMs are technically far superior to eccentric machines, they have some disadvantages, namely: complex construction; require more spare punches and dies. The quality of tablets is influenced by the amount of pressure, pressing speed, condition and wear resistance of the press tool, which is subjected to quite a lot of wear and tear, as it experiences heavy loads. The durability of dies is 2-3 times less than that of punches, which is explained by chemical interaction of the matrix material with the tablet mass, rigid loading of the matrix, friction of particles of the pressed material and the tablet against the walls of the matrix;
more difficult preparation for pressing; more labor-intensive cleaning; large variation in mass deviation from the nominal value due to the use of dozens of sets of press tools. Eccentric machines use only one set of press tools and therefore the variation in the mass of individual tablets is less than when pressing on RTM. Based on the above disadvantages it can be concluded that rotary tablet machines are cost-effective only for mass production. Before pressing, any tablet machine must be set up, calibrated and adjusted optimally. Before starting the process, a test tabletting process is carried out by starting the machine manually, which results in the required tablet weight, proper strength and disintegration as well as the elimination of external imperfections.

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