СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Preparation of suppository base

Preparation of suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Preparation of suppository base

Preparation of suppository base

The stage of preparation of the suppository base begins with the sizing of its components. In the first stainless steel reactor with a steam jacket melt paraffin, in the second reactor melt hydrofat by supplying steam into the steam jacket. The heated hydrofat is transferred to the reactor with pre-melted paraffin by means of a pump. The mixture is heated to a temperature of 60-70 ° C and cocoa butter is added. In order to avoid changes in the modification of cocoa butter, heating should not exceed 70 ° C and be prolonged. After complete melting of the base it is stirred for 40 min with a stirrer. The melting point and the time of complete deformation are determined in the finished base.

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Information updated: 28 / 09 / 2026
Available for
Production: 1 year на оборудование для приготовления суппозиторной основы

Model: Suppository base

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Our service and customer service

The preparation of the suppository mass is carried out in a reactor, where the ready base is fed with compressed air and drug substances are added. As an example, the LT series reactor-mixer manufactured by the Italian company ZUMA s.r.l. is used. Mixers of this series are designed for the preparation of suppository mass, creams, ointments, etc. and are available in four sizes with the volume of the working tank 30, 60, 140 and 250 liters. The working tank of the reactor is a polished stainless steel tank with a water jacket for heating and melting of the mixture. The tank can be rotated by 90° for easy draining and washing. The agitator blades of the reactor are equipped with scraper blades. All working parts of the apparatus are made of stainless steel. The mixer reactor is equipped with safety guards and is manufactured according to international standard.

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Technical specifications

If the melting temperature of the base is higher or lower than the specified one, then paraffin or hydrofat is introduced into the base heated to 60-70 ° C with thorough mixing. The base is filtered through a druk-filter using a brass mesh or belting, analyzed by melting temperature, solidification and time of full deformation and transferred to the apparatus department.
Druk filters are pressurized capacitive filters. Druk-filters are vertical vessels (usually with a jacket) with an elliptical bottom.
The vessel filter housing can be open or closed. The upper part of the housing is fed with the slurry to be separated. The filtrate is discharged from the lower part. During filtration, compressed gas is fed into the slurry-filled housing.

Additional information

The filter baffle is located on the false bottom. The resulting sludge is washed, dried and discharged by means of an agitator through a hatch located on the side of the housing or in the center of the false bottom. In some designs, the sludge is removed after lowering the false bottom by moving the filter cloth belt, which passes through the regeneration chamber at the end of the sludge discharge. Druk filters are known, the body of which can be rotated by 90-180° in the trunnions fixed on its cylindrical part. Druk filters are used to separate medium and well-filtered suspensions in medium and low-tonnage productions.

Order status tracking

Roman Tsibulsky +79853643808 now online

Sebastian
How to contact you for shipment tracking ? Industrial vibrating screen VS-04. 02/10/2026 17:16

Roman Tsibulsky
Good afternoon, Sebastian, My WhastApp is +79853643808, Manager Natalia +79153808881 during business hours and except weekends. 02/10/2026 17:20

Logan
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 02/10/2026 17:26

Roman Tsibulsky
Logan, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 02/10/2026 17:29

Dylan
Waiting for delivery to Couresaire of a TR-02 hard gelatin capsule polishing machine. What about it? 02/10/2026 17:36

Roman Tsibulsky
Hello Dylan, on your order we inform you that before lunch the driver will contact you to clarify the time and place of unloading. 02/10/2026 17:40

Lucas
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 02/10/2026 17:46

Roman Tsibulsky
Hello Lucas, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 02/10/2026 17:50

Benjamin
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Boston 02/10/2026 17:56

Roman Tsibulsky
Hello Benjamin, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 02/10/2026 17:57

Riley
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Bucharest, do you deliver to the terminal or to the actual address? 02/10/2026 18:06

Roman Tsibulsky
Hello Riley, we ship all over Europe and the US including to Bucharest . The price in the catalog includes any delivery our customer asks for. 02/10/2026 18:07

Evelyn
HX-6 Plastic Tube Filling and Sealing Machine in Vienna? Price delivery terms and conditions 02/10/2026 18:16

Roman Tsibulsky
Evelyn, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 02/10/2026 18:16

Benjamin
Vacuum lyophilic freeze dryer LG-30, can we get faster than the contract ? 02/10/2026 18:26

Roman Tsibulsky
Hello Benjamin, Shipments go through several time stages. Manufacturing, delivery from the factory to the warehouse in Beijing or Shanghai, waiting for batch collection, customs clearance and delivery. It's hard to predict. 02/10/2026 18:28

Mia
Good day, tell me need delivery in Oklahoma City to the settlement in the distance of 20 km. Can you organize this? 02/10/2026 18:36

Roman Tsibulsky
Mia, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 02/10/2026 18:37

Joseph
Vacuum lyophilic freeze dryer LG-30, can we get faster than the contract ? 02/10/2026 18:46

Roman Tsibulsky
Hello Joseph, Shipments go through several time stages. Manufacturing, delivery from the factory to the warehouse in Beijing or Shanghai, waiting for batch collection, customs clearance and delivery. It's hard to predict. 02/10/2026 18:48