Microspheres (pellets) are a new type of solid dosage form. Recently, in the pharmaceutical industry, drug manufacturers have been producing microspheres, or pellets (from the English pellet — ball, pellet, pellet), as the final or intermediate type of dosage form for the production of finished dosage forms. Microspheres are increasingly being used in the production...
Equipment for assembling, cutting and laying adhesive plaster (Leucoplastrum), or elastic external adhesive plaster (Emplastrum adhaesivum elasticum externum). It is possible that the assembly, cutting and capping of a small and medium-sized adhesive plaster is carried out on an automated EURO type in the Italian company EURVSICMA. Depending on the material and size of the...
After the tableting process, the finished tablet most often needs to be coated. In the modern pharmaceutical industry, the importance of tablet coating is increasing.
In modern pharmaceutical production, the following methods of applying film coatings are used.Coating in drums; coating in a fluidized bed (spraying from above, spraying from below, coating tangentially); technology of jet fluidization. Coating in drums has already been discussed in the section "Methods and equipment for coating".The technological parameters of the film coating process are:...
Soft gelatin capsules can also vary in capacity, although there is no clear standardization, unlike hard capsules. Suture soft capsules can hold up to 7.5 ml. The capacity of the rolls of the machine, with which the capsules are formed, filled and sealed, is measured in units called minim. At the same time, 1 minim...
The reproduction and accuracy of dosing depends on the characteristics of the filler, the filling method and the type of filling machine. Active substances for filling into solid gelatin capsules must meet the following requirements: the contents must be released from the capsule, providing high bioavailability; when using automatic filling machines, active substances must have...
There are three main methods of industrial production of gelatin capsules: immersion method, rotary matrix and drip. It should be noted that for the production of solid capsules, the dipping method has found wide application in industry, being essentially the only one. However, to obtain soft gelatin capsules (with drip sealing), the method is currently...
The application of film coatings is carried out in apparatuses for combined granulation, drying and coating processes. A distinctive feature is the lower location of the nozzle. There are two possible ways of organizing the process: applying a film coating directly to crystals or granules containing a medicinal substance; conducting a preliminary stage — layering...
Alu/Alu packaging equipmentis an improved model of this type of machine. It is characterized by ease of operation and maintenance, easy to clean, has a friendly interface and many functions. The system is controlled by a PLC controller. Full automatic control ensures the accuracy and good appearance of the packaging. Advanced and compact form of…
The needle sealing and package cutting equipment uses parchment paper and packaging film suitable for processing and sectional cutting as packaging materials, such as, for example, nonwovens, impregnated paper, BOPP and CPP films, and other similar materials. PLC computer control system, window opening, rejection, localization and cutting at the same time (PLC manufactured in Japan, touch…
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