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The image of the topography of the surface of the object is visually observed on the screen of the monitor and recorded on wide-format film. The principle of operation of an electron scanning microscope is as follows: a narrow beam of electrons with a kinetic energy of the order of 1–25 kV enters the sample under study. Electrons of the reflected beam (secondary electrons) released by atoms located on the surface form an image recorded on the screen or microphotographs. In order to avoid damage to the sample or its combustion, the sample is preliminarily coated with a conductive layer (usually a thin layer of gold), which prevents surface charging. The method of electron scanning microscopy allows high-resolution determination of the structure of the studied samples, the shape and size of particles, pore size, pore size distribution, surface porosity and visualize pore geometry.
Specifications
This once again proves the fact that the finer the particles, the lower the flowability.
The technological characteristics described above of powdered drug substances are of paramount importance in the development of the composition and technology of tablet forms, which should provide the necessary bioavailability and, accordingly, the effectiveness and safety of the drug.
The technological characteristics of the powders are established quickly enough, the methods for their determination are simple and not difficult, therefore, these methods are currently widely used in the pharmaceutical industry to carry out mass control of all medicinal substances entering the production.
Tips for our customers
Typically, in pharmaceutical enterprises, dispersion analysis of drug substances is carried out using such available methods as sieve analysis, microscopy, using a laser particle analyzer, etc. This allows even at the stage of selection of firms supplying pharmaceutical substances to exclude non-standard substances from entering the developed technological process and to ensure the high quality of domestic tablet preparations. To determine properties such as surface, shape and particle size, the method of electron scanning microscopy can be used. Stationary electron scanning microscope designed to study the topography (microgeometry) of a solid surface by the method of secondary electron emission.
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LARGE CATALOG OF PHARMACEUTICAL EQUIPMENT
A constantly updated catalog of various pharmaceutical equipment with photos, descriptions, videos and prices.
SPECIALISTS AND TECHNOLOGIES
We have extensive connections in the pharmaceutical environment, we will find any specialist, we will help with the development of equipment and technologies
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- Logo Tablet Pill
- Automatic hydraulic tablet press
- Tablet Press Rotary Tablet Press
- Spray gun for coating tablets, dragees and nuts
- Machine for filling liquids in plastic and glass bottles
- Silica gel bagging machine
- Blister Packing Machine
- Printer for printing on tablets, dragees and capsules, sweets
- Equipment for filling liquids and sealing glass ampoules
- Mechanical glue filling machine in aluminum tubes
- Washing plastic and glass penicillin vials and ampoules
- Automatic Plastic Ampoule Forming Machine
- Screw system for feeding powder into hoppers of machines and containers
- V-shaped mixer for mixing dry powder material
- Emulsifier of cream and ointments for the cosmetics industry
- Machine for packing blisters of tablets, gelatin capsules and dragees
- Semi-automatic machine for filling steel barrels with liquid
- The machine for filling medicinal decoctions in a plastic bag
- Induction Welding Machine Aluminum Control Membrane
- Automatic compact doy pack machine
- The printer for printing on any surface of the expiration date and date
- Cardboard Box Cellophane Wrapping Machine
- High-precision high-speed electronic detector for weight control
- Melting analyzer to analyze the melting suppository process
- Melting analyzer to determine the melting point of drugs
- An analyzer for measuring the speed and degree of dissolution of tablets
- Gelatin Viscosity Analyzer
- Laboratory device for determining the hardness of tablets and granules
- Magnetic mixer for mixing solutions and liquids
- Constant Temperature Vacuum Drying Oven
- Electronically controlled peristaltic pumps
- Emulsifier for pharmaceutical and cosmetic ointments and cosmetics
- Knife type laboratory mill with raw material loading
- Semi-automatic machine for granules, dragees, boilies
- Pneumatic machine for dispensing liquids, creams and ointments
- Printer for embossing on the package batch number and expiration date
- Compact rotary tablet press for tablet pressing
- Tablet press for the chemical and food industries
- Tablet Press Rotary Tablet Press
- Coating pan for coating tablets and capsules
- Equipment for packing powders in penicillin vials
- Machine for dosed filling tubes with ointment and cream
- Hard Gelatin Capsule Powder Filling Machine
- Spray dryer for fine powder
- Dosing machine for feeding powders into plastic cans
- Equipment for polishing and removing dust from gelatin capsules
- Machine for counting and filling tablets and capsules into plastic bottles
- The device for the vacuum transportation of powders and bulk products
- Granulator for dry and wet granulation of powder masses
- Laboratory Vacuum Freeze Dryer
- Orientation equipment for plastic bottles
- Desktop Vacuum Sealing Machine for Plastic Bags
- Packing machine for packing piece products in flow packs
- Packing machine for tablets and capsules in soft strip packaging
- Bulk packing of bulk materials in plastic and paper bags
- Equipment for individual packing of tea in pyramids
- Labeling machine for glass and plastic bottles
- Checker Dust Remover and Tablet Dispenser
- Gelatin Gel Strength Testing System
- Moisture analyzer for analyzing the moisture content of powder or granules
- Transparency analyzer for measuring gelatin transparency
- Device analyzer for measuring tablet hardness
- The analyzer for measuring the thickness of gelatin capsules and tablets
- Tester for monitoring the process of decomposition of solids
- Tablet solubility, abrasion and hardness meter
- Multi-Purpose Laboratory Powder Mixer
- Capsule or tablet blister filling machine
- Vibrating screen for industrial use
- Fluid heating machine with integrated magnetic mixer
- Hard gelatine capsule powder filling capsule
- Digital pump dispenser for filling liquids into ampoules and vials
- Semi-automatic capsule for filling capsule powder