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In addition, the heated pipeline protects the product from solidification. However, when producing suppositories on lipophilic bases (plastic film is usually used for their molding), which have a more liquid consistency and a low melting point (32-37 ° C), a peristaltic pump is used.
This is due to the fact that the active substances introduced into the base in the form of powder fraction can settle in the unheated pipeline or tank when the machine stops and during the slow passage of the product through the pipeline. The use of peristaltic pump allows to maintain the necessary temperature of the product, excludes its stagnation in the pipeline and settling of active substances, providing homogeneity of the suppository mass consistency. Cells are filled by inserting the filling needle into the cell opening, through which the liquid suppository mass enters. All process data is displayed on the touch screen, which is also used to set the filling volume of the cells. After the cells have been filled, the suppository belt enters the cooling unit. The product cooling process can be carried out in two or four stages, depending on the solidification time of the components that make up the suppository mass. Two-stage cooling utilizes two cooling spiral chambers installed in series, and four chambers are used for four-stage cooling. The time of two-stage cooling is 9 min and four-stage cooling is 18 min. Thanks to the spiral tracks, the suppositories are cooled on both sides by a temperature-controlled air flow until the product is fully solidified, thus obtaining the optimal shape.
The cooled contour cells are fed into the sealing unit. At first, the suppository strip is preheated, after which the top of the contour cells is sealed. The use of the preheating stage, as well as in the molding unit, ensures qualitative and reliable sealing of the package.
After sealing the cells, the code or date is applied, the cells are perforated for easy cell separation and the top edge of the tape is trimmed. The suppositories can come out of the machine in the form of a ribbon (if docking with the cartoning machine is carried out through a special docking module) or in the form of cut blisters. The number of suppositories in a blister is set from the machine control panel.
Pharmaceutical Glossary
Technical specifications
Therefore, the use in the cooling stage allows a significant reduction in the curing time of the product, as well as making the process manageable and controllable. When the suppository mass in the cooling unit is fully cured, the spool with the finished product is transferred to an automatic container sealing and ribbon cutting machine. In the machine, the ribbon is sealed and cut into sections with the specified number of cells. Sealing is carried out by pulse heating and compression. The stable temperature of the sealing tool is ensured by two high-power fans. Simultaneously with sealing the coding operation is carried out. Coding of containers (series and date) is carried out by extrusion by means of a cliché. After sealing, the edges of the tape are automatically processed. This operation allows to significantly improve the appearance of the finished product. To control the process of cutting the tape into strips of a given length, a digital programmer is used, which sets the cutting range from 1 to 10 suppositories. The machines allow the production of suppositories in contoured cell packs made of aluminum and thermoformed plastic. In contrast to medium-capacity production, in the high-capacity industrial machines, the molding of the contour cells is done directly in the machine. High-precision machine with low noise level and high productivity (up to 22 thousand suppositories per hour). The machine is controlled through a programmable logic controller (PLC). The automatic machine has an optimal mode of operation, which avoids the formation of waste in the production process. The production process of suppositories begins with the formation of contoured cell packaging made of plastic film or aluminum foil. Two rolls of plastic film (one roll – printed, from which the front part of the suppository package is molded, the second roll – unprinted) are installed on roll holders. Plastic films from both rolls simultaneously enter the pre-heating unit, where they are quickly heated to the required temperature. The required film tension is regulated by a special device. The preheated plastic films are fed to the contour cell-shaped plastic film heat-welding unit.
Additional information
In this way, the two films are joined together over the entire surface, except for the interior of the cells. Then the film enters the molding unit, where, by blowing compressed air into the unsoldered space, the contoured cell is volumetrically molded. At the same time, a small hole remains open in the upper part of each cell, through which the cell is subsequently filled with suppository mass. In case of aluminum foil packaging production, the contour cell forming unit dismantles the units designed to work with plastic film – film preheating unit, film heat-welding unit and forming unit. The aluminum foil cell forming unit is installed in their place. Due to its heavy weight, this unit is installed in the machine by means of a lifting mechanism. It should be noted that the units are common for both types of packaging. Two rolls of aluminum foil (one printed and one unprinted) are installed on the roll holders. The foil tension is adjusted by the device. The aluminum foil strips from both rolls are fed in parallel to the contour cell forming unit, where the contour of the cell is mechanically extruded on the surface of the aluminum foil strip. Thus, in contrast to plastic foil, no preheating or compressed air is required for forming cells from aluminum foil. Two unconnected ribbons with the molded halves of the contoured cells exit the forming unit. The two strips are then joined together so that the cell halves are completely overlapping and are fed into the assembly where the strips are heated and finally thermally welded together. At the same time, as in the case of the plastic film, an opening is left open at the top of each cell for the introduction of the suppository mass. In this way, the contour cell formed of plastic film or aluminum foil serves at the same time as an injection mold. The plastic or aluminum foil-formed package is fed into the filling unit in the form of a ribbon. The suppository mass, heated to a temperature of 30-80 ° C, depending on the active ingredient and base from the reservoir comes through a pipeline to the volumetric dispenser, from where the product is automatically loaded into the cells.
To maintain the required temperature and homogeneous consistency of the suppository mass, the 80-liter reservoir is equipped with a water jacket and a stirrer. In the production of glycerin-based suppositories with a viscous consistency (they are usually molded in aluminum foil), the agitator provides homogeneous mixing of the suppository mass, heated to a temperature of about 80 ° C.
Order status tracking
To what address to send you samples of bottles and caps to send them to the factory ? Regards Sebastian. 22/12/2025 01:19
Good day, Sebastian We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 22/12/2025 01:19
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 22/12/2025 01:29
Hello Elizabeth, Transportation has advised that as stipulated in the contract driver will definitely deliver the box to your address. We apologize. 22/12/2025 01:29
Roman hello, what about the automatic filling and sealing machine for sterile ampoules ABF-4D-1, invoice #101. 22/12/2025 01:39
Good afternoon, Dylan! We are making a request to the manufacturer. Tomorrow we will send photos and video of testing to your e-mail. 22/12/2025 01:41
Automatic blister packaging machine for PVC+cardboard LW-35 with delivery to Memphis. We want to track the delivery status. 22/12/2025 01:49
William, hello. The shipment has already arrived. Now it is in the warehouse of the transportation company. Your manager will contact you to clarify the time of delivery to your city. 22/12/2025 01:52
Roman hello, what about the automatic filling and sealing machine for sterile ampoules ABF-4D-1, invoice #101. 22/12/2025 01:59
Good afternoon, Savannah! We are making a request to the manufacturer. Tomorrow we will send photos and video of testing to your e-mail. 22/12/2025 02:03
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 22/12/2025 02:09
Good afternoon Violet, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. before lunch we will get a reply from the manufacturer on the final time frame. 22/12/2025 02:10
Good day, tell me need delivery in El Paso to the settlement in the distance of 20 km. Can you organize this? 22/12/2025 02:19
Carter, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 22/12/2025 02:22
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 22/12/2025 02:29
Amelia, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 22/12/2025 02:31
For shipping to Luxembourg City do you have to pay anything extra ? 22/12/2025 02:39
Good day Layla, In our catalog, all prices are inclusive of shipping to the customer's door. Delivery to Luxembourg City is included. 22/12/2025 02:43
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 22/12/2025 02:49
Chloe, Checking delivery status. The shipment is already in Santorini warehouse. Please arrange for pickup. 22/12/2025 02:53
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COATING TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
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