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In addition, the heated pipeline protects the product from solidification. However, when producing suppositories on lipophilic bases (plastic film is usually used for their molding), which have a more liquid consistency and a low melting point (32-37 ° C), a peristaltic pump is used.
This is due to the fact that the active substances introduced into the base in the form of powder fraction can settle in the unheated pipeline or tank when the machine stops and during the slow passage of the product through the pipeline. The use of peristaltic pump allows to maintain the necessary temperature of the product, excludes its stagnation in the pipeline and settling of active substances, providing homogeneity of the suppository mass consistency. Cells are filled by inserting the filling needle into the cell opening, through which the liquid suppository mass enters. All process data is displayed on the touch screen, which is also used to set the filling volume of the cells. After the cells have been filled, the suppository belt enters the cooling unit. The product cooling process can be carried out in two or four stages, depending on the solidification time of the components that make up the suppository mass. Two-stage cooling utilizes two cooling spiral chambers installed in series, and four chambers are used for four-stage cooling. The time of two-stage cooling is 9 min and four-stage cooling is 18 min. Thanks to the spiral tracks, the suppositories are cooled on both sides by a temperature-controlled air flow until the product is fully solidified, thus obtaining the optimal shape.
The cooled contour cells are fed into the sealing unit. At first, the suppository strip is preheated, after which the top of the contour cells is sealed. The use of the preheating stage, as well as in the molding unit, ensures qualitative and reliable sealing of the package.
After sealing the cells, the code or date is applied, the cells are perforated for easy cell separation and the top edge of the tape is trimmed. The suppositories can come out of the machine in the form of a ribbon (if docking with the cartoning machine is carried out through a special docking module) or in the form of cut blisters. The number of suppositories in a blister is set from the machine control panel.
Pharmaceutical Glossary
Technical specifications
Therefore, the use in the cooling stage allows a significant reduction in the curing time of the product, as well as making the process manageable and controllable. When the suppository mass in the cooling unit is fully cured, the spool with the finished product is transferred to an automatic container sealing and ribbon cutting machine. In the machine, the ribbon is sealed and cut into sections with the specified number of cells. Sealing is carried out by pulse heating and compression. The stable temperature of the sealing tool is ensured by two high-power fans. Simultaneously with sealing the coding operation is carried out. Coding of containers (series and date) is carried out by extrusion by means of a cliché. After sealing, the edges of the tape are automatically processed. This operation allows to significantly improve the appearance of the finished product. To control the process of cutting the tape into strips of a given length, a digital programmer is used, which sets the cutting range from 1 to 10 suppositories. The machines allow the production of suppositories in contoured cell packs made of aluminum and thermoformed plastic. In contrast to medium-capacity production, in the high-capacity industrial machines, the molding of the contour cells is done directly in the machine. High-precision machine with low noise level and high productivity (up to 22 thousand suppositories per hour). The machine is controlled through a programmable logic controller (PLC). The automatic machine has an optimal mode of operation, which avoids the formation of waste in the production process. The production process of suppositories begins with the formation of contoured cell packaging made of plastic film or aluminum foil. Two rolls of plastic film (one roll – printed, from which the front part of the suppository package is molded, the second roll – unprinted) are installed on roll holders. Plastic films from both rolls simultaneously enter the pre-heating unit, where they are quickly heated to the required temperature. The required film tension is regulated by a special device. The preheated plastic films are fed to the contour cell-shaped plastic film heat-welding unit.
Additional information
In this way, the two films are joined together over the entire surface, except for the interior of the cells. Then the film enters the molding unit, where, by blowing compressed air into the unsoldered space, the contoured cell is volumetrically molded. At the same time, a small hole remains open in the upper part of each cell, through which the cell is subsequently filled with suppository mass. In case of aluminum foil packaging production, the contour cell forming unit dismantles the units designed to work with plastic film – film preheating unit, film heat-welding unit and forming unit. The aluminum foil cell forming unit is installed in their place. Due to its heavy weight, this unit is installed in the machine by means of a lifting mechanism. It should be noted that the units are common for both types of packaging. Two rolls of aluminum foil (one printed and one unprinted) are installed on the roll holders. The foil tension is adjusted by the device. The aluminum foil strips from both rolls are fed in parallel to the contour cell forming unit, where the contour of the cell is mechanically extruded on the surface of the aluminum foil strip. Thus, in contrast to plastic foil, no preheating or compressed air is required for forming cells from aluminum foil. Two unconnected ribbons with the molded halves of the contoured cells exit the forming unit. The two strips are then joined together so that the cell halves are completely overlapping and are fed into the assembly where the strips are heated and finally thermally welded together. At the same time, as in the case of the plastic film, an opening is left open at the top of each cell for the introduction of the suppository mass. In this way, the contour cell formed of plastic film or aluminum foil serves at the same time as an injection mold. The plastic or aluminum foil-formed package is fed into the filling unit in the form of a ribbon. The suppository mass, heated to a temperature of 30-80 ° C, depending on the active ingredient and base from the reservoir comes through a pipeline to the volumetric dispenser, from where the product is automatically loaded into the cells.
To maintain the required temperature and homogeneous consistency of the suppository mass, the 80-liter reservoir is equipped with a water jacket and a stirrer. In the production of glycerin-based suppositories with a viscous consistency (they are usually molded in aluminum foil), the agitator provides homogeneous mixing of the suppository mass, heated to a temperature of about 80 ° C.
Order status tracking
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 10/06/2025 06:54
Hello Nova, We are on time, In the afternoon a driver will contact you about unloading. 10/06/2025 06:57
Good day, delivery time of semi-automatic drum filling machine DF-10 to Alexandrovka, will the courier call us? 10/06/2025 07:04
Emilia, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 10/06/2025 07:04
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 10/06/2025 07:14
Hello David, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 10/06/2025 07:17
Please inform me about the status of the order Rotary tablet press RZ-10A in Kansas City ? 10/06/2025 07:24
Good afternoon, Lily. We have contacted the carrier, delivery is scheduled as stipulated in the contract. Please let us know when you receive it. Thank you. 10/06/2025 07:24
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 10/06/2025 07:34
Hello Aria, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 10/06/2025 07:34
Please inform me about the status of the order Rotary tablet press RZ-10A in Washington ? 10/06/2025 07:44
Good afternoon, Lily. We have contacted the carrier, delivery is scheduled in the interval from 10:00-12:00. Please let us know when you receive it. Thank you. 10/06/2025 07:44
In Kuressaare ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 10/06/2025 07:54
Good afternoon, Zoe! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 10/06/2025 07:56
Excuse me, I have important information, please do not deliver my shipment, automatic filling and sealing machine for glass ampoules ALG-10 to Marburg, but immediately upon arrival send it to Oslo. 10/06/2025 08:04
Hello Lucas, we will try to resolve this issue for you. 10/06/2025 08:05
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Las Vegas. 10/06/2025 08:14
Good day Matthew, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Las Vegas is included in the price. 10/06/2025 08:15
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 10/06/2025 08:24
Liam, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 10/06/2025 08:25
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS