СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

Fluidized bed coating of fine particles at supercritical conditions is a new emerging technology for the encapsulation of thermolabile products. Supercritical fluids are unique solvents because their densities are similar to those of liquids, while viscosity and diffusion coefficient are close to these values for gases. Atomization of supercritical solutions allows the production of submicron-sized droplets and particles, as well as sputtering on and on, other particles. Since the cohesive and adhesive forces for supercritical solutions are small compared to those for organic solvents, the capillary compression force is negligible.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide our customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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Information updated: 07 / 05 / 2026
Available for
Production: 1 year на оборудование для инкапсуляции методом нанесения покрытий в псевдоожиженном слое

Model: Encapsulation

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Export to any world countries. Air, sea and road transport with the necessary documents.
Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
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Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.

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Technical specifications

This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.

Additional information

For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.

Order status tracking

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Riley
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 12/05/2026 05:33

Roman Tsibulsky
Hello Riley, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 12/05/2026 05:36

Elizabeth
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 12/05/2026 05:43

Roman Tsibulsky
Good afternoon Elizabeth, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. in the interval from 14:00-16:00 we will get a reply from the manufacturer on the final time frame. 12/05/2026 05:46

Gabriel
I've been calling your office since this morning, and no one's picking up the phone. 12/05/2026 05:53

Roman Tsibulsky
Good afternoon, Gabriel! The office will be open from 9:00 GMT. We'll be in touch. 12/05/2026 05:56

Violet
Good day, I want tomorrow until 17:30 to get FF-02 tablet and capsule filling machine in Paris? 12/05/2026 06:03

Roman Tsibulsky
Good afternoon, Violet! We have contacted the transportation company, your shipment is arriving in Paris without delay. Please wait for a call from a representative of Business Lines. 12/05/2026 06:07

Michael
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 12/05/2026 06:13

Roman Tsibulsky
Hello Michael, Our manager Natalia after lunch will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Butrint in 15 days. 12/05/2026 06:17

Harper
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 12/05/2026 06:23

Roman Tsibulsky
Good afternoon Harper, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. tomorrow until 16:30 we will get a reply from the manufacturer on the final time frame. 12/05/2026 06:24

David
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Arlington 12/05/2026 06:33

Roman Tsibulsky
Hello David, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 12/05/2026 06:34

Olivia
Good afternoon, I am hoping in the interval from 10:00-12:00 to get the UNIC 600A Tablet Press in Stavanger ! Please comment. 12/05/2026 06:43

Roman Tsibulsky
Good day, Olivia! Our manager has communicated with the delivery service, the equipment will be delivered to Stavanger at your address. Please let us know when you receive it. 12/05/2026 06:45

Daniel
Horizontal granulator for organic fertilizers JU-80, the price is up to date ? Delivery time to Barcelona? Urgent. 12/05/2026 06:53

Roman Tsibulsky
Daniel, Please read carefully the description of this model in our catalog. Prices are current. Timing 1-1.5 months. 12/05/2026 06:54

Michael
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 12/05/2026 07:03

Roman Tsibulsky
Hello Michael, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 12/05/2026 07:03