СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

Fluidized bed coating of fine particles at supercritical conditions is a new emerging technology for the encapsulation of thermolabile products. Supercritical fluids are unique solvents because their densities are similar to those of liquids, while viscosity and diffusion coefficient are close to these values for gases. Atomization of supercritical solutions allows the production of submicron-sized droplets and particles, as well as sputtering on and on, other particles. Since the cohesive and adhesive forces for supercritical solutions are small compared to those for organic solvents, the capillary compression force is negligible.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide our customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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Information updated: 28 / 05 / 2026
Available for
Production: 1 year на оборудование для инкапсуляции методом нанесения покрытий в псевдоожиженном слое

Model: Encapsulation

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Assume responsibility and risks for delivery, insurance and customs cargo clearance in USA. Further transit to countries.
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On arrival in USA delivery of equipment to your door.
Consultation from our specialist with 20 years of experience throughout the life of the equipment.
Export to any world countries. Air, sea and road transport with the necessary documents.
Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
Guaranteed up to 15% discount on our services when subsequent purchase in the pharmaceutical equipment catalog.
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Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.

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Technical specifications

This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.

Additional information

For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.

Order status tracking

Roman Tsibulsky +79853643808 now online

Henry
The BB-152 liquid filling machine arrived from you today, remember us ? Where's the paperwork? 01/06/2026 07:26

Roman Tsibulsky
{The original shipping documents will be delivered to Rome tomorrow until 15:30. Please send the signed copies to us. 01/06/2026 07:28

Scarlett
Please inform me about the status of the order Rotary tablet press RZ-10A in Long Beach ? 01/06/2026 07:36

Roman Tsibulsky
Good afternoon, Scarlett. We have contacted the carrier, delivery is scheduled In the afternoon. Please let us know when you receive it. Thank you. 01/06/2026 07:37

Liam
When is the SL-20 soft strip tablet packaging machine scheduled to be delivered to Zurich ? 01/06/2026 07:46

Roman Tsibulsky
Hello Liam, Expect tomorrow until 16:30. Once received, please let us know. 01/06/2026 07:48

Sophia
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 01/06/2026 07:56

Roman Tsibulsky
Good day, Sophia! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 01/06/2026 07:59

Jayden
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 01/06/2026 08:06

Roman Tsibulsky
Hello Jayden, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in USA to 50 working ( not calendar) days. Action taken. 01/06/2026 08:10

Mason
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 01/06/2026 08:16

Roman Tsibulsky
Good day, Mason! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 01/06/2026 08:19

Grace
You have to pay for delivery to Tossa de Mar over and above the delivery amount in the contract ? 01/06/2026 08:26

Roman Tsibulsky
Grace, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 01/06/2026 08:29

Evelyn
Remember me? There's a delivery in the Helsinki 01/06/2026 08:36

Roman Tsibulsky
Evelyn, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be tomorrow until 17:30 in Helsinki . 01/06/2026 08:39

Joseph
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 01/06/2026 08:46

Roman Tsibulsky
Joseph, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 01/06/2026 08:49

Mia
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Bakersfield. 01/06/2026 08:56

Roman Tsibulsky
Good day Mia, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Bakersfield is included in the price. 01/06/2026 08:58