СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

Fluidized bed coating of fine particles at supercritical conditions is a new emerging technology for the encapsulation of thermolabile products. Supercritical fluids are unique solvents because their densities are similar to those of liquids, while viscosity and diffusion coefficient are close to these values for gases. Atomization of supercritical solutions allows the production of submicron-sized droplets and particles, as well as sputtering on and on, other particles. Since the cohesive and adhesive forces for supercritical solutions are small compared to those for organic solvents, the capillary compression force is negligible.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide our customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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Information updated: 28 / 10 / 2026
Available for
Production: 1 year на оборудование для инкапсуляции методом нанесения покрытий в псевдоожиженном слое

Model: Encapsulation

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Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

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Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.

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Technical specifications

This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.

Additional information

For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.

Order status tracking

Roman Tsibulsky +79853643808 now online

Alexander
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 01/11/2026 20:58

Roman Tsibulsky
Alexander, Checking delivery status. The shipment is already in Mont St. Michel warehouse. Please arrange for pickup. 01/11/2026 21:01

Nova
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 01/11/2026 21:08

Roman Tsibulsky
Nova, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer tomorrow until 18: 30. We will report back immediately. 01/11/2026 21:08

Noah
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 01/11/2026 21:18

Roman Tsibulsky
Noah, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 01/11/2026 21:20

William
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 01/11/2026 21:28

Roman Tsibulsky
Hello William, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 01/11/2026 21:31

Aria
HX-9 plastic tube filling and sealing machine bought a month ago, arrival status in Lucca. 01/11/2026 21:38

Roman Tsibulsky
Hello Aria, Delivery status checked, the day after tomorrow is arriving at Lucca . The driver will call you beforehand. 01/11/2026 21:39

Elizabeth
We received our order (BG-150 film coating boiler) in the box there was no spraying nozzle !!! 01/11/2026 21:48

Roman Tsibulsky
Hello Elizabeth, we checked with the factory. Your nozzle was not received in time for the shipment of the main machine. We will now deliver it to you by DHL express mail. 01/11/2026 21:52

Savannah
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Marburg ? 01/11/2026 21:58

Roman Tsibulsky
Good afternoon, Savannah! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 01/11/2026 21:59

Chloe
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 01/11/2026 22:08

Roman Tsibulsky
Chloe, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Oakland ? Contact Natalia, she will send the contract and invoice. 01/11/2026 22:12

Victoria
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 01/11/2026 22:18

Roman Tsibulsky
Victoria, Checking delivery status. The shipment is already in Edinburgh warehouse. Please arrange for pickup. 01/11/2026 22:19

Aiden
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 01/11/2026 22:28

Roman Tsibulsky
Aiden, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer In the afternoon. We will report back immediately. 01/11/2026 22:28