СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

Fluidized bed coating of fine particles at supercritical conditions is a new emerging technology for the encapsulation of thermolabile products. Supercritical fluids are unique solvents because their densities are similar to those of liquids, while viscosity and diffusion coefficient are close to these values for gases. Atomization of supercritical solutions allows the production of submicron-sized droplets and particles, as well as sputtering on and on, other particles. Since the cohesive and adhesive forces for supercritical solutions are small compared to those for organic solvents, the capillary compression force is negligible.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide our customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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Information updated: 09 / 06 / 2026
Available for
Production: 1 year на оборудование для инкапсуляции методом нанесения покрытий в псевдоожиженном слое

Model: Encapsulation

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Consultation from our specialist with 20 years of experience throughout the life of the equipment.
Export to any world countries. Air, sea and road transport with the necessary documents.
Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
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Equipment leasing with advance payment from 10%

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Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.

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Technical specifications

This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.

Additional information

For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.

Order status tracking

Roman Tsibulsky +79853643808 now online

Benjamin
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 21/06/2026 08:13

Roman Tsibulsky
Hello Benjamin, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 21/06/2026 08:17

Alexander
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 21/06/2026 08:23

Roman Tsibulsky
Alexander, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 21/06/2026 08:24

Alexander
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 21/06/2026 08:33

Roman Tsibulsky
Hello Alexander, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 21/06/2026 08:36

Layla
Rotary tablet press RZK-25 I want to order with delivery to Berlin 21/06/2026 08:43

Roman Tsibulsky
Good day, Layla We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 21/06/2026 08:44

Alexander
You have to pay for delivery to Leicester over and above the delivery amount in the contract ? 21/06/2026 08:53

Roman Tsibulsky
Alexander, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 21/06/2026 08:53

William
Tell me the NJ-120 automatic capsule machine went ? 21/06/2026 09:03

Roman Tsibulsky
William, good afternoon. Yes, already as stipulated in the contract you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 21/06/2026 09:06

Ethan
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 21/06/2026 09:13

Roman Tsibulsky
Hello Ethan, Our manager Natalia as agreed will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Antwerp in 15 days. 21/06/2026 09:13

James
To what address to send you samples of bottles and caps to send them to the factory ? Regards James. 21/06/2026 09:23

Roman Tsibulsky
Good day, James We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 21/06/2026 09:26

David
In Marburg ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 21/06/2026 09:33

Roman Tsibulsky
Good afternoon, David! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 21/06/2026 09:36

Elijah
The BB-152 liquid filling machine arrived from you today, remember us ? Where's the paperwork? 21/06/2026 09:43

Roman Tsibulsky
{The original shipping documents will be delivered to Athens as agreed. Please send the signed copies to us. 21/06/2026 09:46