7581
5906820
Video review of the model
Our service and customer service
Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.
Pharmaceutical Glossary
Technical specifications
This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.
Additional information
For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.
Order status tracking
Roman Tsibulsky +79853643808
now online
Jack
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 02/05/2024 11:06
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 02/05/2024 11:06
Roman Tsibulsky
Hello Jack, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 02/05/2024 11:09
Hello Jack, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 02/05/2024 11:09
Henry
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 02/05/2024 11:16
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 02/05/2024 11:16
Roman Tsibulsky
Henry, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 02/05/2024 11:19
Henry, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 02/05/2024 11:19
Victoria
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Florence, do you deliver to the terminal or to the actual address? 02/05/2024 11:26
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Florence, do you deliver to the terminal or to the actual address? 02/05/2024 11:26
Roman Tsibulsky
Hello Victoria, we deliver all over USA including to Florence . The price in the catalog includes any delivery our customer asks for. 02/05/2024 11:29
Hello Victoria, we deliver all over USA including to Florence . The price in the catalog includes any delivery our customer asks for. 02/05/2024 11:29
Alexander
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 02/05/2024 11:36
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 02/05/2024 11:36
Roman Tsibulsky
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Alexander, this chat is only for tracking shipments. 02/05/2024 11:39
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Alexander, this chat is only for tracking shipments. 02/05/2024 11:39
Michael
Remember me? There's a delivery in the Luxembourg City 02/05/2024 11:46
Remember me? There's a delivery in the Luxembourg City 02/05/2024 11:46
Roman Tsibulsky
Michael, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be before lunch in Luxembourg City . 02/05/2024 11:49
Michael, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be before lunch in Luxembourg City . 02/05/2024 11:49
Aiden
Good day, I want as stipulated in the contract to get FF-02 tablet and capsule filling machine in Dublin? 02/05/2024 11:56
Good day, I want as stipulated in the contract to get FF-02 tablet and capsule filling machine in Dublin? 02/05/2024 11:56
Roman Tsibulsky
Good afternoon, Aiden! We have contacted the transportation company, your shipment is arriving in Dublin without delay. Please wait for a call from a representative of Business Lines. 02/05/2024 11:58
Good afternoon, Aiden! We have contacted the transportation company, your shipment is arriving in Dublin without delay. Please wait for a call from a representative of Business Lines. 02/05/2024 11:58
Aubrey
When is the SL-20 soft strip tablet packaging machine scheduled to be delivered to Strasbourg ? 02/05/2024 12:06
When is the SL-20 soft strip tablet packaging machine scheduled to be delivered to Strasbourg ? 02/05/2024 12:06
Roman Tsibulsky
Hello Aubrey, Expect before lunch. Once received, please let us know. 02/05/2024 12:09
Hello Aubrey, Expect before lunch. Once received, please let us know. 02/05/2024 12:09
Stella
You have to pay for delivery to Oxford over and above the delivery amount in the contract ? 02/05/2024 12:16
You have to pay for delivery to Oxford over and above the delivery amount in the contract ? 02/05/2024 12:16
Roman Tsibulsky
Stella, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 02/05/2024 12:17
Stella, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 02/05/2024 12:17
Abigail
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Tallinn, do you deliver to the terminal or to the actual address? 02/05/2024 12:26
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Tallinn, do you deliver to the terminal or to the actual address? 02/05/2024 12:26
Roman Tsibulsky
Hello Abigail, we deliver all over USA including to Tallinn . The price in the catalog includes any delivery our customer asks for. 02/05/2024 12:28
Hello Abigail, we deliver all over USA including to Tallinn . The price in the catalog includes any delivery our customer asks for. 02/05/2024 12:28
Ellie
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 02/05/2024 12:36
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 02/05/2024 12:36
Roman Tsibulsky
Hello Ellie, The shipment has arrived at the customs terminal, tomorrow until 13:30 is scheduled to be transferred to the transportation company. 02/05/2024 12:38
Hello Ellie, The shipment has arrived at the customs terminal, tomorrow until 13:30 is scheduled to be transferred to the transportation company. 02/05/2024 12:38
Write us a message
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR COATING TABLETS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- AUTOMATIC CARTONING MACHINES
- FLOW-PACK PACKAGING MACHINES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- PERISTALTIC PUMPS DISPENSERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- FLOW-PACK PACKAGING MACHINES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- DESKTOP EQUIPMENT FOR MIXING POWDERS