MEDICINE MANUFACTURING FROM EXPERTS

DRAGEE COATINGS ON TABLETS, DRAGEES, CAPSULES, NUTS, CHEWING GUMS

The term “coated coating” comes from the French word “dragee” and means “applying a sugar coating”. A drained tablet consists of a core tablet containing a medicinal substance (substance) and a coating containing several excipients. The core tablet must be mechanically strong. Tablets to be drained should not have a flat shape to avoid sticking together. Let’s consider one of the old methods of coating — sugar coating. Sugar coating is an effective way of applying large layers of coatings, primarily to mask the taste. This type of coating is used for temperature-sensitive and brittle solid dosage forms. The first stage of this technology is the spraying of a solution for spraying onto a particle (tablet, pellet). The air supplied to the device evaporates the…

HOW TO ORGANIZE THE PACKING OF POWDER INTO BAGS?

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1. Mixing the powder. You need to understand exactly what type of powder mixer you need. I see that you have a 5% corn syrup supplement. Syrup, as I understand it, in liquid form. This creates a big problem with high-quality mixing with dry powder, and later with its packing in bags. I suggest you the following course of action: a) Buy a small paddle mixer for 20 liters or a little more – or a pastry dough mixer. In it, mix your 5% syrup with a small amount of any powder from your list. Then dry it, grind it into powder and inject it dry into the bulk of the powder. b) Buy a large mixer for 200 liters for mixing dry powder. It…

VACUUM AND ATMOSPHERIC SPRAY FREEZE DRYING

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The vacuum sublimation dehydration method combines the advantages of two well—known dehydration methods – freezing and vacuum drying. During freezing, undesirable changes in the properties of the product are minimal, and during subsequent drying, frozen moisture is removed, which allows the products to be stored in appropriate packaging (for a year or more) at an unregulated ambient temperature. The energy costs for organizing the sublimation process in vacuum are 15-20 times higher than the similar costs for thermal drying. In addition, vacuum freeze dryers are characterized by high cost, high operating costs and complexity of maintenance. Among other things, according to such qualitative characteristics of the product as flowability, shape and particle size, vacuum freeze drying is not always suitable. Whatever task you have in…

DRAGEE COATINGS ON TABLETS, DRAGEES, CAPSULES, NUTS, CHEWING GUMS

HOW TO ORGANIZE THE PACKING OF POWDER INTO BAGS?

VACUUM AND ATMOSPHERIC SPRAY FREEZE DRYING

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