Laboratory lyophilic freeze dryer “RL-01”
Material: – European stainless steel AISI 316L
Number of shelves: – 1 shelf
Shelf size: – 360mm (length) x 280mm (width) x 25mm (thickness)
Useful area of shelves: – 0,1 m2
Distance between shelves: – 100mm
Temperature range: -55°C to +80°C
Shelf cooling rate: +20°C to -40°C 60 min (no load)
Shelf heating rate: +20°C to -40°C 60 min.
Temperature stability: – ±1°C
Front door (rectangular): – Polymethylmethacrylate (PMMA)
Door locking method: – Manual locking.
Condenser: – in the chamber
Condenser material: – European stainless steel AISI 316L, with internal coils.
Ice capacity in condenser: – 2 kg
Minimum temperature: -65°C
Condenser cooling rate: +20°C to -40°C 30 min.
Defrost mode: Normal temperature
Condenser chamber front door: – polymethyl methacrylate (PMMA)
Hydraulic power unit: – None
Compressed air supply unit: – AirTac
Pneumatic solenoid valve: – AirTac
Clamping force: – Adjustable
Heater: – 0.2 kW
Heating speed: – 1°C/min
Vacuum pump: – Leybold
Standard flow rate: – 8.11 m3/h
Maximum residual pressure in the chamber: – 1 Pa
Pumping out: from atm. to 10 Pa – 15 min.
Leakage rate: – 5×10-3 Pa.m3/sec.
Cooling method: – cascade cooling system
Minimum shelf temperature: -55°C
Minimum condenser temperature: -65°C
Refrigerant (without chlorofluorocarbon):
– Main circuit: R-508B / auxiliary circuit: R-407C
Cooling: – by air
Compressor brand: – Embrco
Number of compressors: – 2
Power: 1/3 hp.
PLC: OMRON manufacturer
Touch Screen: OMRON
Screen size: 5 inches
Resolution: 320×240 dpi
UPS – not available
Software: – from OEM
Electrical components: – ABB company
System design: – with external vacuum pump
Size of lyophilizer: 780mm (length) x 650mm (width) x 760mm (height)
Voltage: – 220V
Power consumption: – 4 kW
Ambient temperature during operation : – 5-25°C
Weight : 150 kg
Weight with packing : 200 kg

The process of operation of this equipment consists of placing vials with liquid material into the freeze drying chamber and then obtaining dried powder. Pre-rinsed and dried glass penicillin vials are used, into which the material is poured. Then the vials are capped with special rubber stoppers having side slits in the part that enters the neck of the vial. Corking is made not to the end but by 50%, only to fix the rubber stopper in the neck of the bottle. Subsequently, the liquid is pumped out of the bottle through these slits by vacuum. In the final stage, after complete dehydration of the material is a complete closure of the plug with hydraulic movable shelves. Thus drying takes place in a vacuum environment, and then the material is finally packed in a vacuum. This allows (unlike other types of similar drying) to keep the material in vacuum for a period of 1-2 years. After the bottles are vacuumized the chamber can be opened and automatic or semi-automatic fixing of the rubber stopper with an aluminum cap can be performed. The caps are put on the neck of the vial and sealed. According to the statements of the manufacturer of the equipment, with such technology it is possible to fully restore the viability of the material after dehydration when opening the vacuum packaging within 4-5 hours. Storage in a vacuum of the material is possible at a temperature not exceeding +36 degrees C. Since in the process of dehydration (water removal) the equipment dehydrates the material, the recovery takes place with distilled water. The removed water is frozen in the chamber, then drained after defrosting and it is possible to control how many ml came out of the dried product, in order to restore later exactly the same amount of water. This is an important point. According to the manufacturer’s statements not all materials can be turned into powder, some biological materials when dehydrated turn into a jelly-like substance, which is also recovered with distilled water. The manufacturer of the equipment has a large laboratory, which together with the experienced production can carry out any research of your material, get samples of products in dried form and packed in vacuum for further research by customers.