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In reality, there are no sharp boundaries between the three stages of pressing, as the processes occurring in the second stage take place in the first and third stages, and we can only speak about the predominant role of individual processes in each of the pressing stages. Studies have established that the nature of compaction of granules and powder particles during pressing depends on their strength. As mentioned in Sect. 4.4, tablets are produced by three methods: wet granulation, dry granulation and direct pressing.
Pharmaceutical Glossary
Technical specifications
In the second stage of pressing, as the pressing pressure increases, the material is intensively compacted by filling the voids and various types of deformation, which contribute to a more compact packing of the material. The resulting deformations can be of the following types: deformation due to elasticity helps the particles to wedge into each other, which increases the contact surface; deformation due to plastic properties makes the particles change their shape and fit more tightly together; deformation determined by the brittleness of the material, characterized by the destruction of the pressed material, occurs only when the stresses occurring in the pressed material exceed the yield strength of the material.
Additional information
In this case there is a mechanical destruction of material particles into smaller ones, accompanied by a significant increase in surface energy, which creates conditions for the emergence of contacts between particles. At the second stage of pressing a compact porous body with sufficient mechanical strength is formed from the bulk material. At the third stage of pressing at high pressure values, when the mechanical strength of tablets changes insignificantly, there is possibly a volumetric compression of powder particles and granules without a noticeable increase in contact surfaces.
Order status tracking
Remember me? There's a delivery in the Zagreb 24/11/2024 23:15
Savannah, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be tomorrow until 16:30 in Zagreb . 24/11/2024 23:17
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 24/11/2024 23:25
Hello Liam, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 24/11/2024 23:27
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Figueres ? 24/11/2024 23:35
Good afternoon, Henry! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 24/11/2024 23:38
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 24/11/2024 23:45
Hello Nova, Transportation has advised that between 12:00-14:00 driver will definitely deliver the box to your address. We apologize. 24/11/2024 23:46
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Porto, do you deliver to the terminal or to the actual address? 24/11/2024 23:55
Hello Ava, we deliver all over USA including to Porto . The price in the catalog includes any delivery our customer asks for. 24/11/2024 23:57
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 25/11/2024 00:05
Hello Dylan, We are on time, after lunch a driver will contact you about unloading. 25/11/2024 00:09
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 25/11/2024 00:15
Aiden, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 25/11/2024 00:18
RZW-29 rotary tablet press in Tallinn. Regards, Samuel. 25/11/2024 00:25
Samuel, Delivery will be made In the afternoon to Tallinn . Please have the movers ready. The weight of the equipment is heavy. 25/11/2024 00:27
We're from New Jersey, we paid for the equipment on your invoice yesterday. Has the payment been received? How long will it take to deliver to us? 25/11/2024 00:35
Lucas, hello. Payment is credited to our settlement account. Term of manufacture of your equipment by the factory 20 working days, delivery from the factory to our warehouse in the USA 1 month, delivery from the warehouse in San Francisco 15 calendar days. 25/11/2024 00:36
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 25/11/2024 00:45
Hello Dylan, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 25/11/2024 00:48
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- AUTOMATIC CARTONING MACHINES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION