СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

There are three ways of introducing medicine into the suppository base, which are determined by the physical and chemical properties of the components: All water-soluble components are introduced in the form of aqueous solutions; fat-soluble substances are introduced in the form of fat solutions; substances insoluble in water and fat are introduced in the form of suspensions of powders melted into the bases. The resulting solutions or suspensions are called concentrates.

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Information updated: 08 / 04 / 2026
Available for
Production: 1 year на оборудование для введения в суппозиторную основу лекарственных веществ

Model: Suppository base

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Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

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Equipment leasing with advance payment from 10%

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Our service and customer service

The ready concentrate is pumped by a pump (through a hose with a capron sieve) into a reactor with a suppository base. Preparation of suppository mass is carried out with constant stirring and heating to a temperature of 45-50 ° C. At the end of the process, the product is analyzed for homogeneity of mixing of components, check the time of complete deformation, as well as the solidification and melting temperature of the mass. If positive results are obtained, the suppository mass is submitted for pouring into molds.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

At the stage of medicine preparation, water-soluble components are dissolved in water heated to 45 ° C, and fat-soluble components are dissolved in a portion of the melted fat base. The resulting concentrates are filtered and then mixed with the remaining base. Substances insoluble in water and base, introduced in the form of suspension as follows: pre-crushed medicine substances mixed in a reactor with an equal or one and a half times the amount of base, heated to a temperature of 40-50 ° C.

Additional information

The obtained concentrate is cooled and milled in colloid mills. For treatment of thermolabile substances three-roll masheters are used. In addition, to obtain high-quality suspensions can be used rotary-pulsation devices, rotary-tooth pumps and other equipment. To obtain the required degree of dispersibility of the medicine substance introduced into the base on the type of suspension, the time of rubbing the concentrate lasts from 2 to 4 h.

Order status tracking

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Andrew
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 17/04/2026 13:23

Roman Tsibulsky
Hello Andrew, Transportation has advised that tomorrow by lunchtime driver will definitely deliver the box to your address. We apologize. 17/04/2026 13:27

Victoria
Good afternoon, please confirm that in the interval from 14:00-16:00 we will receive our shipment in Dubrovnik? Contact the transportation company. 17/04/2026 13:33

Roman Tsibulsky
Hello Victoria ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Dubrovnik in a few days. Please expect it. 17/04/2026 13:36

Zoe
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 17/04/2026 13:43

Roman Tsibulsky
Zoe, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 17/04/2026 13:46

Luna
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 17/04/2026 13:53

Roman Tsibulsky
Hello Luna, Transportation has advised that closer to evening driver will definitely deliver the box to your address. We apologize. 17/04/2026 13:53

Nova
When is the SL-20 soft strip tablet packaging machine scheduled to be delivered to Edinburgh ? 17/04/2026 14:03

Roman Tsibulsky
Hello Nova, Expect tomorrow until 12:30. Once received, please let us know. 17/04/2026 14:04

Grace
Good day, I want as agreed to get FF-02 tablet and capsule filling machine in USA? 17/04/2026 14:13

Roman Tsibulsky
Good afternoon, Grace! We have contacted the transportation company, your shipment is arriving in USA without delay. Please wait for a call from a representative of Business Lines. 17/04/2026 14:15

Liam
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Krakow, do you deliver to the terminal or to the actual address? 17/04/2026 14:23

Roman Tsibulsky
Hello Liam, we deliver all over USA including to Krakow . The price in the catalog includes any delivery our customer asks for. 17/04/2026 14:25

Abigail
Tell me the NJ-120 automatic capsule machine went ? 17/04/2026 14:33

Roman Tsibulsky
Abigail, good afternoon. Yes, already after lunch you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 17/04/2026 14:34

Abigail
Hello, is it possible to buy your blistering machine for tablets and capsules MN-80 1 piece with delivery to Wichita ( Europe) ? How much time for delivery ? 17/04/2026 14:43

Roman Tsibulsky
Abigail, hello! We have many customers from your city. Delivery to this region is made by EMC. 17/04/2026 14:46

Hannah
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Munich, do you deliver to the terminal or to the actual address? 17/04/2026 14:53

Roman Tsibulsky
Hello Hannah, we ship all over Europe and the US including to Munich . The price in the catalog includes any delivery our customer asks for. 17/04/2026 14:57