СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

There are three ways of introducing medicine into the suppository base, which are determined by the physical and chemical properties of the components: All water-soluble components are introduced in the form of aqueous solutions; fat-soluble substances are introduced in the form of fat solutions; substances insoluble in water and fat are introduced in the form of suspensions of powders melted into the bases. The resulting solutions or suspensions are called concentrates.

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Information updated: 08 / 10 / 2026
Available for
Production: 1 year на оборудование для введения в суппозиторную основу лекарственных веществ

Model: Suppository base

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Our service and customer service

The ready concentrate is pumped by a pump (through a hose with a capron sieve) into a reactor with a suppository base. Preparation of suppository mass is carried out with constant stirring and heating to a temperature of 45-50 ° C. At the end of the process, the product is analyzed for homogeneity of mixing of components, check the time of complete deformation, as well as the solidification and melting temperature of the mass. If positive results are obtained, the suppository mass is submitted for pouring into molds.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

At the stage of medicine preparation, water-soluble components are dissolved in water heated to 45 ° C, and fat-soluble components are dissolved in a portion of the melted fat base. The resulting concentrates are filtered and then mixed with the remaining base. Substances insoluble in water and base, introduced in the form of suspension as follows: pre-crushed medicine substances mixed in a reactor with an equal or one and a half times the amount of base, heated to a temperature of 40-50 ° C.

Additional information

The obtained concentrate is cooled and milled in colloid mills. For treatment of thermolabile substances three-roll masheters are used. In addition, to obtain high-quality suspensions can be used rotary-pulsation devices, rotary-tooth pumps and other equipment. To obtain the required degree of dispersibility of the medicine substance introduced into the base on the type of suspension, the time of rubbing the concentrate lasts from 2 to 4 h.

Order status tracking

Roman Tsibulsky +79853643808 now online

Joseph
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 16/10/2026 09:59

Roman Tsibulsky
Good afternoon Joseph, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. as stipulated in the contract we will get a reply from the manufacturer on the final time frame. 16/10/2026 10:00

David
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 16/10/2026 10:09

Roman Tsibulsky
David, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Miami ? Contact Natalia, she will send the contract and invoice. 16/10/2026 10:11

Liam
Today we were promised delivery of a blister machine for MN-14 tablets and capsules, remember us ? No one's called us back. 16/10/2026 10:19

Roman Tsibulsky
Hello Liam, Our manager Natalya tomorrow until 16:30 will dial the driver, also we ask you yourself to the transportation company. 16/10/2026 10:20

Lucy
Waiting for delivery to Hum of a TR-02 hard gelatin capsule polishing machine. What about it? 16/10/2026 10:29

Roman Tsibulsky
Hello Lucy, on your order we inform you that after lunch the driver will contact you to clarify the time and place of unloading. 16/10/2026 10:33

Hannah
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in New Orleans 16/10/2026 10:39

Roman Tsibulsky
Hello Hannah, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 16/10/2026 10:39

Evelyn
Rotary tablet press RZK-25 I want to order with delivery to Berlin 16/10/2026 10:49

Roman Tsibulsky
Good day, Evelyn We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 16/10/2026 10:52

Liam
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 16/10/2026 10:59

Roman Tsibulsky
Hello Liam, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Honolulu . 16/10/2026 10:59

Liam
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 16/10/2026 11:09

Roman Tsibulsky
Hello Liam, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 16/10/2026 11:11

Elizabeth
Good afternoon, please confirm that tomorrow by lunchtime we will receive our shipment in Split? Contact the transportation company. 16/10/2026 11:19

Roman Tsibulsky
Hello Elizabeth ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Split in a few days. Please expect it. 16/10/2026 11:20

Elijah
Excuse me, I have important information, please do not deliver my shipment, automatic filling and sealing machine for glass ampoules ALG-10 to Sarajevo, but immediately upon arrival send it to Paris. 16/10/2026 11:29

Roman Tsibulsky
Hello Elijah, we will try to resolve this issue for you. 16/10/2026 11:32