СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

There are three ways of introducing medicine into the suppository base, which are determined by the physical and chemical properties of the components: All water-soluble components are introduced in the form of aqueous solutions; fat-soluble substances are introduced in the form of fat solutions; substances insoluble in water and fat are introduced in the form of suspensions of powders melted into the bases. The resulting solutions or suspensions are called concentrates.

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Information updated: 09 / 10 / 2026
Available for
Production: 1 year на оборудование для введения в суппозиторную основу лекарственных веществ

Model: Suppository base

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Our service and customer service

The ready concentrate is pumped by a pump (through a hose with a capron sieve) into a reactor with a suppository base. Preparation of suppository mass is carried out with constant stirring and heating to a temperature of 45-50 ° C. At the end of the process, the product is analyzed for homogeneity of mixing of components, check the time of complete deformation, as well as the solidification and melting temperature of the mass. If positive results are obtained, the suppository mass is submitted for pouring into molds.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

At the stage of medicine preparation, water-soluble components are dissolved in water heated to 45 ° C, and fat-soluble components are dissolved in a portion of the melted fat base. The resulting concentrates are filtered and then mixed with the remaining base. Substances insoluble in water and base, introduced in the form of suspension as follows: pre-crushed medicine substances mixed in a reactor with an equal or one and a half times the amount of base, heated to a temperature of 40-50 ° C.

Additional information

The obtained concentrate is cooled and milled in colloid mills. For treatment of thermolabile substances three-roll masheters are used. In addition, to obtain high-quality suspensions can be used rotary-pulsation devices, rotary-tooth pumps and other equipment. To obtain the required degree of dispersibility of the medicine substance introduced into the base on the type of suspension, the time of rubbing the concentrate lasts from 2 to 4 h.

Order status tracking

Roman Tsibulsky +79853643808 now online

Jackson
Good day, delivery time of semi-automatic drum filling machine DF-10 to Jurmala, will the courier call us? 20/10/2026 03:12

Roman Tsibulsky
Jackson, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 20/10/2026 03:15

Hannah
Please inform me about the status of the order Rotary tablet press RZ-10A in Oklahoma City ? 20/10/2026 03:22

Roman Tsibulsky
Good afternoon, Hannah. We have contacted the carrier, delivery is scheduled between 16:00-18:00. Please let us know when you receive it. Thank you. 20/10/2026 03:26

Logan
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 20/10/2026 03:32

Roman Tsibulsky
Logan, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Wichita ? Contact Natalia, she will send the contract and invoice. 20/10/2026 03:32

John
Vacuum lyophilic freeze dryer LG-30, can we get faster than the contract ? 20/10/2026 03:42

Roman Tsibulsky
Hello John, Shipments go through several time stages. Manufacturing, delivery from the factory to the warehouse in Beijing or Shanghai, waiting for batch collection, customs clearance and delivery. It's hard to predict. 20/10/2026 03:43

Amelia
Good afternoon, please confirm that closer to evening we will receive our shipment in Crete? Contact the transportation company. 20/10/2026 03:52

Roman Tsibulsky
Hello Amelia ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Crete in a few days. Please expect it. 20/10/2026 03:55

Michael
HX-9 plastic tube filling and sealing machine bought a month ago, arrival status in Sarajevo. 20/10/2026 04:02

Roman Tsibulsky
Hello Michael, Delivery status checked, tomorrow until 13:30 is arriving at Sarajevo . The driver will call you beforehand. 20/10/2026 04:02

Liam
Tell me the NJ-120 automatic capsule machine went ? 20/10/2026 04:12

Roman Tsibulsky
Liam, good afternoon. Yes, already the day after tomorrow you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 20/10/2026 04:15

Hannah
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 20/10/2026 04:22

Roman Tsibulsky
Hannah, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 20/10/2026 04:25

Elizabeth
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 20/10/2026 04:32

Roman Tsibulsky
Hello Elizabeth, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in Bruges to 50 working ( not calendar) days. Action taken. 20/10/2026 04:34

Liam
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Skradin ? 20/10/2026 04:42

Roman Tsibulsky
Good afternoon, Liam! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 20/10/2026 04:44