СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / FILM-COATING OF TABLETS / Encapsulation by fluidized bed coating method

Encapsulation by fluidized bed coating method

Fluidized bed coating of fine particles at supercritical conditions is a new emerging technology for the encapsulation of thermolabile products. Supercritical fluids are unique solvents because their densities are similar to those of liquids, while viscosity and diffusion coefficient are close to these values for gases. Atomization of supercritical solutions allows the production of submicron-sized droplets and particles, as well as sputtering on and on, other particles. Since the cohesive and adhesive forces for supercritical solutions are small compared to those for organic solvents, the capillary compression force is negligible.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide our customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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Information updated : 09 / 12 / 2025
In stock
Manufacturer : 1 year for Encapsulation by fluidized bed coating method

Model: Encapsulation

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Consultation from our specialist with 20 years of experience throughout the life of the equipment.
Export to any world countries. Air, sea and road transport with the necessary documents.
Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
Guaranteed up to 15% discount on our services when subsequent purchase in the pharmaceutical equipment catalog.
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Equipment leasing with advance payment from 10%

Rotary tablet press for tablets up to 50 mm ZL-15

Rotary tablet press for tablets up to 60 mm NP-8

Rotary tablet press for tablets up to 50 mm NP-15

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Our service and customer service

Thus, the new technology of fluidized bed encapsulation under supercritical conditions allows coating thermolabile materials with particle sizes not exceeding 100 μm without particle agglomeration. The technology is increasingly being introduced into modern pharmaceutical production and requires further study to obtain effective and safe new generation drugs. Nowadays, the encapsulation process has gained new development due to the possibility of changing the pharmacological properties of drugs and the development of innovative equipment. Solid, soft and liquid active drug substances can be encapsulated in different types of shells, so this material is highlighted in a separate chapter.

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Technical specifications

This feature allows particles smaller than 100 µm to be encapsulated in the fluidized bed without forming agglomerates. At the same time supercritical fluid is used both as a solvent for the dispersed solution and as a fluidizing agent. This unit consists of three blocks: carbon dioxide supply system; extractor, in which carbon dioxide saturation with coating material takes place; high-pressure reactor. The volume of the reactor is 500 cm3; the maximum pressure in the system is 30 MPa, the maximum temperature is 373 °C. Prior to the process, the reactor is loaded with encapsulated material.

Additional information

For fluidization of the particle bed, pure carbon dioxide is fed from the bottom of the apparatus through the perforated bottom. It is experimentally confirmed that with increasing pressure in the system the minimum fluidization rate decreases. The encapsulation process starts after thermal equilibrium is established in the reactor. The carbon dioxide passes through an extractor where it is saturated with the coating agent and dispersed by a nozzle in the reactor. The dispersion results in submicron-sized droplets that settle on the surface of the particles and spread to form a thin film. After coating, the particles are allowed to dry.

Order status tracking

Roman Tsibulsky +79853643808 now online

Isabella
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 21/12/2025 04:13

Roman Tsibulsky
Isabella, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 21/12/2025 04:17

Oliver
Hello, is it possible to buy your blistering machine for tablets and capsules MN-80 1 piece with delivery to Oklahoma City ( Europe) ? How much time for delivery ? 21/12/2025 04:23

Roman Tsibulsky
Oliver, hello! We have many customers from your city. Delivery to this region is made by EMC. 21/12/2025 04:25

Matthew
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 21/12/2025 04:33

Roman Tsibulsky
Good afternoon, Matthew! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 21/12/2025 04:35

Aiden
For shipping to Zurich do you have to pay anything extra ? 21/12/2025 04:43

Roman Tsibulsky
Good day Aiden, In our catalog, all prices are inclusive of shipping to the customer's door. Delivery to Zurich is included. 21/12/2025 04:43

Noah
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 21/12/2025 04:53

Roman Tsibulsky
Hello Noah, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 21/12/2025 04:55

Ruby
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Corpus Christi. Please confirm the delivery time. 21/12/2025 05:03

Roman Tsibulsky
Good afternoon Ruby, your shipment has left. Arrival time closer to evening. The driver will call you back later. Please organize prompt unloading. 21/12/2025 05:05

William
In Lucca ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 21/12/2025 05:13

Roman Tsibulsky
Good afternoon, William! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 21/12/2025 05:15

Mia
Good day , Electronic conveyor belt package weight detector DK-05 when will we receive in Rome ? 21/12/2025 05:23

Roman Tsibulsky
Hello Mia, your shipment is in the customs warehouse, tomorrow until 12:30 your manager Natalia will contact you. 21/12/2025 05:24

Lily
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Porto, then I want to buy an automatic capsule machine model GN-28 21/12/2025 05:33

Roman Tsibulsky
Good afternoon, Lily! On the first question - the shipment will arrive in Porto closer to evening. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 21/12/2025 05:33

Ruby
Please inform me about the status of the order Rotary tablet press RZ-10A in Riverside ? 21/12/2025 05:43

Roman Tsibulsky
Good afternoon, Ruby. We have contacted the carrier, delivery is scheduled in the interval from 10:00-12:00. Please let us know when you receive it. Thank you. 21/12/2025 05:44