MEDICINE MANUFACTURING FROM EXPERTS

PACKAGING OF POWDERED PHARMACEUTICAL SUBSTANCES

1
2
3
4
5
6
7
8

Powders are packed in the following materials. Paper capsules. For their manufacture, the following are used: glued paper is a cellulose mass with a glued layer of animal glue. Such paper is mainly used for packaging hygroscopic and non—volatile powders; waxed and paraffin paper is glued paper impregnated with wax or paraffin. Since it does not allow moisture and gases to pass through, it is used for packaging hygroscopic substances (euphyllin), as well as substances that change under the influence of oxygen in the air and carbon dioxide. Such packaging is not suitable for camphor and menthol, which dissolve in wax and paraffin. In paraffin paper capsules, substances such as analgin, glucose, dibazole, diphenhydramine, etc. are released; parchment paper is obtained from non—glued paper treated…

VALVE-TYPE PLUNGER HOMOGENIZERS

8824

6975568

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15

Valve-type plunger homogenizers are designed for one-, two- and three-stage homogenization. This process takes place in a special valve system, which is the center of the entire homogenization process. When passing through the smallest openings in the valve under high pressure and constant monitoring, the product finds itself in conditions of high turbulence, which is the most effective mechanism for dividing into particles. The degree of fragmentation depends on the hydraulic conditions in the valve slot area. These conditions are mainly determined by the homogenization pressure, which determines the speed of movement of the ointment in the valve slot and its height, which determines the hydraulic radius of the flow. Valve-type homogenizers use multi-plunger high-pressure pumps with three, five and even seven plungers. When the…

SOFT DOSAGE FORMS, THEIR CLASSIFICATION AND PROPERTIES

8824

6975571

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15

The acquaintance of a person with soft medicinal forms occurs in the first days of life, when the caring hands of a mother apply baby cream to the delicate skin of a child. Then, throughout their lives, people use soft medicinal forms of medical appointment for the prevention and treatment of various diseases in dermatology with external therapy of skin lesions of various etiologies, gynecology, proctology, ophthalmology, as well as cosmetics to protect the skin from harmful effects and prolong its beauty and youth. In this chapter, classifications will be given, technologies for the production of soft dosage forms will be considered. Depending on the consistency, degree of viscosity and elasticity, the following can be attributed to soft dosage forms: Ointments; creams; Gels; Pastes; Liniments;…

How to develop the process of filling liquids into bottles?

8215

6969476

1
2
3
4
5
6
7
8
9
10

Usually you need to link each car to the others in the line. 1. You need to wash the vials and dry them before filling. How do you plan for this to work?? Wash and dry small batches of bottles of the same type on the day of work, or for a week or a month? 2. Next, you need to submit empty bottles to the place of filling. Do you have several product positions, do you want to pour everything on one machine, or will each type of product have its own machine? 1200 bottles per hour, in principle, can be filled with a desktop typewriter. That’s just the question – how to seal it and transfer the filled vials to the capping so…

How to develop the process of bottling iodine into vials?

8221

6969537

1
2
3
4
5
6
7
8
9
10
11
12

1. Do you want to use one machine both for syrups and for zelenka and for iodine??? It’s not practical at all. Wash it every time when changing one product to another, and zelenka and especially iodine is a very specific product. My advice is that each product has its own filling machine. 2. No clarifying information is specified – what type of vials, what type of caps, stoppers, etc. By how many ml. you need to pour, what productivity is required per hour, etc. Without this data, I can’t offer anything seriously and responsibly. I am waiting for this information. 3. Label maker – what type of labels are self-adhesive or on glue??? In a circle or in a fragment??? Need a universal machine…

How to develop pharmaceutical production?

8261

6969942

1
2
3
4
5
6
7
8
9
10
11
12

Here are my tips for you. 1. You need to pick up samples of the products that you are going to produce. Examine all the parameters for each position. According to the tablets – what diameter and thickness are they, is there a protective shell, what type of packaging, how many tablets in one package, the size of the package, will the packaging be in a cardboard box? will there be a label application, expiration dates, etc. How many tablets per hour you will need to produce, how many packages per hour you want to receive. Ampoules and solutions are the same. Learn the subtleties of everything you want to produce.

How to organize production of e-cigarette liquids?

8196

6969287

1
2
3
4
5
6
7
8
9
10
11
12

The production of liquids for electronic cigarettes is now being developed by a lot of people. And I see that there will soon be high competition in this niche. The process itself can be divided into 2 stages. 1. Preparation of the liquid itself. 2. Filling, capping and labeling. About the first part – cooking. You must have some kind of chemical technologist who will understand how and under what conditions you need to mix the components of your liquid. Is there a delamination of liquids, is there alcohol, etc. Depending on the components, the mixing equipment is selected. About the second part – filling, capping and labeling. The main consumable part is bottles, spouts, lids, labels. The gravity of the liquid itself is not…

How to organize pressing of rings with thin walls?

8230

6969630

1
2
3
4
5
6
7

First, even if you do not take into account the fact that there will be a hole inside your tablet, but simply consider pressing a tablet with a diameter of 2.2 – 4.5 mm, then the question of feeding powder into such a hole becomes acute. This is possible only with some exceptional flowability of the powder, or forcibly. The powder will not go by gravity into such a hole. Now the same task, but you need to feed the powder evenly around the stem, which forms the inner hole. This is a difficult task, let’s say.

How to develop the production of tablets from powders?

8223

6969554

1
2
3
4
5
6
7
8
9
10
11
12

I suggest starting with the diameter of the tablets and their estimated thickness. If this is not an ordinary cylindrical tablet, then I want to understand its shape. This is necessary to select the press model. You also need to understand what kind of press performance in thousands of tablets per hour you need.

How to develop an original vegetable oil business?

8205

6969381

1
2
3
4
5
6
7
8
9
10
11
12

I want to draw your attention to one equipment and technology that will help you make a new business direction and expand the assortment. My company produces equipment and technology for producing round seamless capsules with oil inside. To date, we have one machine and 2 technologies for obtaining the shell of these capsules – gelatin and from the hangar. Gelatin and agar capsules can be from 3 mm to 14 mm in diameter. There may be oil or fat inside. Now in Europe and other countries, people prefer healthy nutrition and treatment technologies.