PHARMA

Hydrophilic bases for ointments and creams

7906

6765445

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Hydrophilic bases are mixed with water in any ratio. The following ointment bases are hydrophilic: solutions and gels of polysaccharides; solutions and gels of natural and synthetic polymers; phytosterol gels; gels of clay minerals; solutions and gels of proteins. The advantages of hydrophilic bases are: the possibility of introducing a significant amount of aqueous solutions of medicinal substances; ease of release of medicinal substances, which ensures their high bioavailability; good absorbency into the skin, the bases are easily removed from the application site and washed off with water from the skin. The disadvantages of hydrophilic bases include microbial contamination and rapid drying (this property does not apply to polyethylene oxides), as well as incompatibility with a number of medicinal substances and susceptibility to syneresis, a...

Homogenization of ointments and creams

7907

6765446

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The next stage in the production of ointments is homogenization. This is a specific stage, since when mixing, the desired degree of dispersion of medicinal substances is not always achieved. For homogenization, various equipment is used, such as roller or disc masers, millstones and colloidal mills, as well as homogenizers-dispersants. Roller mazeterki have two or three rolls with a smooth surface, rotating towards each other at different speeds, ensuring the transition of ointment from shaft to shaft and increasing the friction between them. Rolls are made of porcelain, basalt or metal. To maintain the optimal temperature of the ointment entering the rolls, they are made hollow so that, if necessary, water can be supplied inside. Mazeterka is a system of three rolls in contact with...

Hydrophobic bases

7907

6765450

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Hydrophobic, or lipophilic, bases are chemically heterogeneous substances and their mixtures with pronounced hydrophobicity. This group includes: fat bases; hydrocarbon bases; silicone bases. Fat bases include animal, vegetable and hydrogenated fats, as well as waxes. Animal fats by chemical nature are triglycerides of higher fatty acids. By their properties, they are close to the fatty secretions of the skin. In addition, fats contain unsaponifiable components, among which cholesterol predominates. Of animal fats, pork fat is the most common — Adeps suillus seu Axungiaporcina (depurata). It is a mixture of triglycerides of stearic, palmitic, oleic and linoleic acids. Pork fat also contains a small amount of cholesterol. It is a white mass almost odorless with a melting point of 34-36 "C. Ointments on pork fat are...

Vacuum production unit for liquid and paste products

7907

6765452

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The German-Swiss company FrymaKoruma, part of the Romaco group of companies, is well known in the world market of pharmaceutical equipment. In Russia, the equipment of this company is also widely represented at many enterprises. In particular, at one of the leading Russian pharmaceutical enterprises JSC Akrikhin, the production of ointments and creams is carried out at the Disho installation of FrymaKoruma. Vacuum is a production plant for liquid and pasty products FrymaKoruma MaxxD, which has the same principle of operation as the Disho installation, but is a more modern development of the company. FrymaKoruma MaxxD is a modular system for the production of emulsions and suspensions with a wide range of viscosity. The main advantages of the plant are high production efficiency, reduced operating...

High speed rotary tablet press GGB-9

8920

6775580

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High-speed rotary tablet press. High-speed tablet press. High pressure. Big pills. Curly pills. Double-sided tablets. High accuracy. High speed. PLC control. Modern, rational design is the basis of excellent product quality. The integration of many years of experience in the production of high-speed tablet presses and modern science and technology provided a new design principle, allowed us to standardize and launch a modular tablet press into mass production. This equipment is characterized by high accuracy, high speed and automation. It is the best choice for high performance and large batch production. GMP design. High quality of the entire stainless steel construction. Special reliable protection system against dust and grease. High visibility of insulating windows to prevent cross contamination. The structure is easily disassembled and assembled,…

High speed rotary tablet press GGB-8

8920

6775581

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High-speed rotary tablet press. High pressure. Big pills. Curly pills. High accuracy. High speed. PLC control. High quality equipment based on advanced technology and reasonable design. The new design of high-speed tablet presses was developed on the basis of many years of production experience and allowed to standardize and launch into mass production a modular high-speed tablet press. The construction of high-quality stainless steel complies with GMP standard, a special protection system against grease and dust, the design of insulating windows facilitates the dismantling of the structure for maintenance and cleaning. The compressor chamber provides a 360° view, which is convenient for monitoring the process and cleaning. GMP design. High quality of the entire stainless steel construction. A special reliable device for protecting insulating windows…

High speed rotary tablet press GGB-7

8920

6775582

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High-speed rotary tablet press. High pressure. Big pills. Curly pills. High accuracy. High speed. PLC control. High quality equipment based on advanced technology and reasonable design. The new design of high-speed tablet presses was developed on the basis of many years of production experience and allowed to standardize and launch into mass production a modular high-speed tablet press. The construction of high-quality stainless steel complies with GMP standard, a special protection system against grease and dust, the design of insulating windows facilitates the dismantling of the structure for maintenance and cleaning. The compressor chamber provides a 360° view, which is convenient for monitoring the process and cleaning. GMP design. High quality of the entire stainless steel construction. A special reliable device for protecting insulating windows…

High speed rotary tablet press GGB-5

8920

6775583

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High-speed rotary tablet press. High pressure. Big pills. Curly pills. High accuracy. High speed. PLC control. High quality equipment based on advanced technology and reasonable design. The new design of high-speed tablet presses was developed on the basis of many years of production experience and allowed to standardize and launch into mass production a modular high-speed tablet press. The construction of high-quality stainless steel complies with GMP standard, a special protection system against grease and dust, the design of insulating windows facilitates the dismantling of the structure for maintenance and cleaning. The compressor chamber provides a 360° view, which is convenient for monitoring the process and cleaning. GMP design. High quality of the entire stainless steel construction. A special reliable device for protecting insulating windows…

High speed double sliding tablet press LTM-3

8920

6775584

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The high-speed double-slip tablet press is equipped with an accurate threaded rod that continuously supports the angle of the supporting structure, allowing precise control of the loading chamber and control of 7-11 punches and matrices, with an acceptable weight difference of about ± 2%. The operating system eliminates the flywheel, which significantly simplified the process, increased speed and preserved the accuracy of loading. Dual transmission, large torque range, large loading capacity, main power of only 7.5 KW. The molds provide a more accurate tablet weight. The multi-level loading system ensures an even distribution of the material. The subsections of the assembly chamber made of acetal are resistant to abrasion and are easy to install. The equipment has the function of manual pressing at high speed and…

High speed double sliding tablet press LTM-2

8920

6775585

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The high-speed double-slip tablet press is equipped with an accurate threaded rod that continuously supports the angle of the supporting structure, allowing precise control of the loading chamber and control of 7-11 punches and matrices, with an acceptable weight difference of about ± 2%. The operating system eliminates the flywheel, which significantly simplified the process, increased speed and preserved the accuracy of loading. Dual transmission, large torque range, large loading capacity, main power of only 7.5 KW. The molds provide a more accurate tablet weight. The multi-level loading system ensures an even distribution of the material. The subsections of the assembly chamber made of acetal are resistant to abrasion and are easy to install. The equipment has the function of manual pressing at high speed and…