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Equipment for combined processes

  • vitamins in tablets
  • Binder for pressing tablets
  • vitamins
  • pharmaceutical granulation
  • Hydraulic Tablet Machines
  • Dosing and mixing of powders
  • sulfur dioxide during pregnancy
  • silicone tube stoppers
  • industrial shredder for garbage
  • hard and soft dosage forms
  • carboxylic acids in medicine
  • Tablet counter

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Equipment for combined processes

SG type apparatus manufactured by NPO “Pharmmedoborudovanie” is used for granulation of powders in a fluidized bed, subsequent drying and powdering. This process is periodic. The body of the apparatus is made of three all-welded sections, successively mounted with each other. The principle of operation is as follows: 30 kg of tablet mixture to be granulated is loaded into the product tank in accordance with the recipe. The cart with the initial components is rolled into the apparatus and lifted. The air temperature required for fanulation is set, the time of mixing, fanulation and drying is set, as well as the cycle and frequency of shaking of bag filters. The fan is switched on by means of a gate which regulates the flow rate of fluidizing air, the required degree of fluidization of the processed mass is set. At preset time intervals the damper in front of the fan is closed, the actuator is switched on, shaking the bag filters, and at certain time intervals the nozzle and the dosing pump supplying the fanulating liquid are automatically switched on – the tablet mixture is fanulated.

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  • Information updated : 09 / 11 / 2024
  • In stock
  • Manufacturer : 1 year for Equipment for combined processes

Model: Equipment for combined processes

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The SpinFlow bottom allows for greater efficiency at exactly those stages of production where it is needed, namely: more intensive and efficient mixing of the product increases the atomization rate, which speeds up the granulation process; a minimum amount of inhomogeneous fraction often eliminates the screening procedure on a fluidized bed granulator; higher granulate densities potentially increase the throughput of the tablet press. Glatt continuous fluidized bed granulators. By dividing the supply air zone into several compartments, process air can be fed into the process at different flow rates and temperatures. Due to this flexibility and the different positioning of the nozzles in the different zones, completely different conditions can be created. Lower and upper atomization is possible. The powder is agglomerated above the first two air inlet compartments, the powder is dried above the third and cooled above the fourth. The finished product is discharged at the end of the process chamber – opposite to the product inlet.

Pharmaceutical Glossary

Dry granulation  — Technological term used in pharmaceutical granule production. This method can be compared to the grinding of large pieces of raw material into granules of uniform fraction. The principle of rubbing the raw material through a metallized stainless steel mesh is used.
Dry granulation Equipment catalog Fluidized bed granulate Granulation granulator Pellets Pharmaceutical equipment Powder granulation sieving Spray drying Wet granulation Wet granulation

Technical specifications

Then the atomization system is switched off and fanulat drying starts. At the end of the whole fanulation cycle, fan 8 is automatically switched off and air supply to the calorifier unit is stopped. The product tank is lowered and the granulate enters the pelletizing process. To avoid entrainment, the air is supplied at a low speed. It is a wheeled apparatus, so it is very convenient for transportation. Technical characteristics of the apparatus type SG: single load: 30-100 kg; duration of granulation and drying: 25-120 min; drying temperature: 20-80 ° C; power consumption: 20 kW. The advantages of this apparatus are in the reduction of the production cycle and production area, reduction of the amount of equipment used and reduction of the labor intensity of the process. Modern devices SG-30 are equipped with a software control panel, granulating liquid is atomized by pneumatic nozzles. However, the specificity of each drug prepatars is such that according to the proven technology of granulation with the use of SG unit another substance in this mode will not be granulated. In such a situation, it is necessary to work out the modes again, to determine the quantity, quality, speed of granulating liquid supply, etc.

Additional information

Glatt batch fluidized bed granulators. These machines combine the processes of granulation, agglomeration, drying and coating, using top and bottom atomization of granulating liquid.
For batch granulation, the dry feedstock is loaded into a receiving container. There it is agitated in a turbulent flow of heated gas while being kept in suspension and agglomerated (granulated) by spraying a suitable binder. The product is then dried to a certain residual moisture content in a process characterized by high heat and mass transfer coefficients. The batch size in various fluidized bed batch machines ranges from 20 g to 1500 kg.
An innovation in fluidized bed technology was Glatt’s development of the SpinFlow bottom, which gives the fluidized bed an additional rotational motion. The resulting tangential forces result in higher granulate density, good flowability, uniform particle size distribution and reduced fine dust formation. The design of this bottom is the basis for an optimal granulation production process in the fluidized bed plant and produces ideal granules for subsequent process steps.

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