A reliable service that is recommended

Substances for film coating of tablets

  • Film coating
  • Application of a film coating on tablets
  • Application of film coatings on tablets
  • Film coating for tablets
  • Doi pack packaging for tea
  • Doy pack packaging
  • monofleral honey what is it
  • acid disposal
  • fourier spectrometer infrared
  • physiotherapy exhaust cabinet
  • the analytical laboratory is
  • Buy filling machine

Get new business partners

Check out our Instagram profile

Add the manager's contact to your WhatsApp

Watch us on our official TikTok account

Subscribe to our official YouTube channel

New business

There is a new industry actively developing in the US – CBD oil encapsulation. Capsules are used for treatment and prevention of diseases. Our company produces equipment for CBD oil encapsulation. WATCH 15 PROMO VIDEOS >>

Substances for film coating of tablets

The main components in most finished film-coated dosage forms are polymers, plasticizers, colorants and solvents (or liquid phase). Polymers. The ideal properties for a polymer are solubility in a wide range of solvents for variability in the composition of the finished dosage form, the ability to create a coating that has suitable mechanical properties, and appropriate solubility in gastrointestinal fluids – such that drug bioavailability is not reduced. The most suitable polymers for film coatings are cellulose ethers, especially hydroxypropyl methyl cellulose (HPMC), hydroxypropyl cellulose (HPC), which produces slightly tacky coatings, and methyl cellulose (MC), although this polymer may retard dissolution of the drug substance.
Alternatives to cellulose ethers are acrylic copolymers (such as methacrylic and methyl methacrylic copolymers) and vinyl polymers (such as polyvinyl alcohol). Polymers can be used alone or in blends to achieve an optimal drug release profile.
However, when mixtures of polymers are used, the optimal ratio of their concentrations must be determined. For example, a mixture of the water-insoluble polymer ethylcellulose and the water-soluble polymer hydroxypropylmethylcellulose can be used for controlled release of a drug substance.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide clients with impressive terms and amazingly fast turnaround time. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

Price: $ 0 HOW TO LOWER THE PRICE?

  • Information updated : 09 / 12 / 2024
  • In stock
  • Manufacturer : 1 year for Substances for film coating of tablets

Model: Film coating on tablets

Expert Services Index

  1. Step-by-step assessment of your task by experts and a detailed discussion of solution options within 24 hours.
  2. Company selection manufacturer and negotiations with selected provider.
  3. Selection, optimal for the client, payment scheme and delivery time.
  4. Assume responsibility and risks for delivery, insurance and customs cargo clearance in USA. Further transit to countries.
  5. Receiving and checking equipmentbefore sending with a video report.
  6. On arrival in USA delivery of equipment to your door.
  7. Consultation from our specialist with 20 years of experience throughout the life of the equipment.
  8. Export to any world countries. Air, sea and road transport with the necessary documents.
  9. Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
Guaranteed up to 15% discount on our services when subsequent purchase in the pharmaceutical equipment catalog.
Only quality equipment from proven suppliers with a long-term reputation.
Flexible payment system. Convenient payment acceptance for customers.


Our service and customer service

At the same time, they can be used to identify the dosage form. Additionally, some physical properties of the coating, such as moisture resistance, can be improved with dyes. Dyes can be classified into water-soluble dyes and insoluble pigments.
Water-soluble dyes cannot be used in film coatings based on organic solvents, they can only be used in coatings based on aqueous compositions. Pigments are preferred because: they are less likely to affect bioavailability than some water-soluble colorants; they help reduce the water permeability of the coating; and they can be used as fillers to increase the total solid content of the coating dispersion without undesirable increases in viscosity. Solvents. Solvents for film coatings may include: alcohols, ketones, esters, chlorinated hydrocarbons and water. Solvents have an important function in the coating formation process as they help in coating the core surface. A good interaction between the solvent and the polymer is necessary to ensure optimum film properties when the coating dries. This initial interaction between solvent and polymer will maximize the elongation of the polymer chain, which in turn will provide good cohesive strength and thus the best mechanical properties. At the same time, an important function of the solvent system is to provide a controlled distribution of the polymer on the core surface to create a homogeneous coating.

Pharmaceutical Glossary

Articles  — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.
Automatic coating equipment Automatic coating machine Automatic coating machine Blog Business Business plan Buy a business Commerce Company Dragee Equipment catalog Film coating Innovation Investments Novelty Pellets Pellets Pharmaceutical machine Pills Production Startup Tablet polisher

Technical specifications

Studies have shown that when the HPMC content in the blend is less than 24%, the release profile depends on the rate of water penetration into the coating, which in turn becomes a determining factor in selecting the ratio of polymer concentrations in the blend.
Most of the polymers used are available in a wide range of molecular weights, which is a major factor in the choice of coating technology. Molecular weight can have a significant effect on coating properties such as viscosity, mechanical strength, and film elasticity.
Plasticizers. A plasticizer is a liquid or solid with a high boiling point. Examples of plasticizers include glycerin, propylene glycol, polyethylene glycol, triacetin, esters of citric acid (e.g., triethyl citrate), esters of phthalic acid (e.g., triethyl phthalate). The introduction of a plasticizer can improve the elasticity of the coating Cracking the risk of mechanical damage and potentially in the coating improve the adhesion of the film coating to the core.
When the plasticizer interacts with the polymer, the minimum film formation temperature may be reduced. To form a quality film, the plasticizer must have high compatibility with the polymer and be permanently retained in the coating, especially if the main objective of the coating is the stability of the dosage form during storage.

Additional information

The scientific literature provides numerous examples of the effect of plasticizer concentration on the physicochemical properties of the film coating and on the release of the drug substance from the coated products. For example, high plasticizer content can reduce the release of metoprolol from Eudragit RS coated microspheres and improve the release stability of theophylline from coated microspheres during storage.
Moreover, the release rate of the drug substance has been shown to be influenced by the type of plasticizer. For example, the release of propanolol from microspheres coated with a mixture of ethylcellulose and Eudragit L100-55 is faster when using the hydrophilic plasticizer triethyl citrate than when using the hydrophobic dibutyl sebacinate. Other studies have shown that the plasticizer can leach out of the coating during dissolution, thus affecting both mechanical properties and the release of LVs.
Adhesion of coating substances during film application causes the formation of undesirable aggregates, and the resulting coatings may be damaged when attempts are made to separate adhering parts. This effect can be neutralized by adding anti-adhesion agents to the coating composition or by applying these agents immediately after the spray chamber. Useful anti-adhesion agents include talc, magnesium stearate, kaolin, etc.
Dyes. Dyes are commonly used to improve the appearance of the dosage form.

Order status tracking


Write us a message

    I, , ,

    Substances for film coating of tablets.

    My contact information:

    Comment:

    Menu