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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Filling gelatin capsules with powders and granules

Filling gelatin capsules with powders and granules

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Filling gelatin capsules with powders and granules

Filling gelatin capsules with powders and granules

Reproducibility and dosing accuracy depend on the characterization of the excipient, the filling method and the type of filling machine. Active substances for filling into hard gelatin capsules must meet the following requirements: the content must be released from the capsule, providing high bioavailability; when using automatic filling machines, active substances must have certain physical, chemical and technological properties, such as: certain size and shape of particles; uniform particle size; homogeneity of mixing; friability (flowability); moisture content; ability to compact under pressure. To fill hard gelatin capsules use automatic machines from different companies, differing in performance, dosing accuracy and the structure of the dispenser.

Whatever your task, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We offer our customers impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

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  • Information updated : 09 / 12 / 2024
  • In stock
  • Manufacturer : 1 year for Filling gelatin capsules with powders and granules

Model: Filling gelatin capsules with powders and granules

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  1. Step-by-step assessment of your task by experts and a detailed discussion of solution options within 24 hours.
  2. Company selection manufacturer and negotiations with selected provider.
  3. Selection, optimal for the client, payment scheme and delivery time.
  4. Assume responsibility and risks for delivery, insurance and customs cargo clearance in USA. Further transit to countries.
  5. Receiving and checking equipmentbefore sending with a video report.
  6. On arrival in USA delivery of equipment to your door.
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  8. Export to any world countries. Air, sea and road transport with the necessary documents.
  9. Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
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The pistons press the powder with high dosing accuracy. The compacted powder is transferred to the capsule body during the powder transfer stage. The powder level can be varied arbitrarily via a level sensor so that the rotation speed of the screw feeder is matched to the powder consumption. The disk method allows the dosage to be adjusted if the powder has poor bulkiness and a tendency to form lumps. The filler mass can be adjusted by changing the pressure and raising or lowering the filler level. This allows capsules to be filled with minimum doses of drugs. This machine has a high capacity (up to 150 thousand capsules per hour), contains a device that provides partial filling of capsules (50% or less), as well as a device that prevents deformation of capsules during the filling process. The machine is equipped with a device that automatically determines the weight of the filled capsule.

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Technical specifications

Depending on the bulkiness and degree of dispersibility (granularity) of the drug substance to be filled, automatic machines work with screw, vacuum or vibrating dispensers. Devices for filling solid capsules can be: manual or semi-automatic, which are designed primarily for the needs of laboratories or small industries (possible capacity is up to 6 thousand capsules per hour). Filling with the help of such devices is carried out by the filling method, and the mass for filling the capsule should be proportional to its volume; fully automatic, designed for industrial production. In this case, the piston method of filling is used with the use of dispensers, and filling devices can be with periodic or continuous movement.

Additional information

Capsules may be filled with pellets or microcapsules using devices that fill by filling, piece-by-piece, double flap, piston, dosing cylinders, or dosing tube methods. Capsule filling with tablets or dragees (or combinations thereof) is accomplished using a flap. If solid gelatin capsules need to be filled with liquids or paste-like fillers, special pumps are used. The most common method of filling capsules is the disk method of dosing, which consists of loading the powder onto a disk containing six groups of holes.

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