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GMP requirements: cleanliness of the device (it must not contaminate the substance); tightness of the device; ease of use. The following requirements are imposed on the processed material: during extrusion the wet mass should have plasticity, fluidity, self-binding properties, density (absence of voids); during spherization the extrudate should have mechanical rigidity, plasticity, absence of adhesion. Starch, talc and microcrystalline cellulose are added to prevent sticking;granules. In conclusion, it should be noted that: the granulation process is an important process in pharmaceutical production; the process of granule formation of the final product depends on the type of equipment used and many other factors; industrial and laboratory granulators are complex systems with a high degree of variability in performance.
Pharmaceutical Glossary
Technical specifications
The rotary-cylinder extruder consists of two cylinders: the first is a rotating cylinder with holes – the pelletizing cylinder, the second is a solid empty cylinder rotating towards the first. During the extrusion process, high pressure is created by the rotation of the two cylinders, resulting in a product of high density and a certain length. The advantages of the rotary-cylinder extruder are the high pressure created during the extrusion process, high density, a defined product length, and no stagnant zones. The disadvantage is the difficulty encountered in cleaning the equipment. The extruder is used for small outputs. Its design resembles that of a tablet machine. The Niro extruder is based on a unique technology of pushing and shearing the extrudate at low speed. This extruder is ideal for sensitive products that can be damaged in other, more intensive systems.
Additional information
The extruder has a wide range of screens of different sizes through which the product passes to optimize pellet diameter, surface characteristics and size distribution. This extruder can be operated in continuous and batch mode, with no stagnant zones or significant product delays. The extruder has a small footprint and is easy to clean, which is an important advantage. The choice of extruder can be made taking into account the following parameters: Principle requirements for the extruder: output; footprint; energy consumption. Methods of further processing or recycling. As recommendations, the following can be highlighted: if it is necessary to obtain homogeneous pellets dried in a fluidized bed, it is better to use a radial-press extruder; if it is necessary to obtain high-density extrudate with further sphericalization, it is more appropriate to use a rotary-cylindrical and press extruder. Scalability.
Order status tracking
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Columbus. 09/09/2026 09:20
Good day Hazel, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Columbus is included in the price. 09/09/2026 09:23
Good day, delivery time of semi-automatic drum filling machine DF-10 to Valletta, will the courier call us? 09/09/2026 09:30
Noah, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 09/09/2026 09:33
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Baltimore. Please confirm the delivery time. 09/09/2026 09:40
Good afternoon Isabella, your shipment has left. Arrival time the day after tomorrow. The driver will call you back later. Please organize prompt unloading. 09/09/2026 09:42
Remember me? There's a delivery in the Rome 09/09/2026 09:50
Lucy, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be In the afternoon in Rome . 09/09/2026 09:52
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Oklahoma City. Please confirm the delivery time. 09/09/2026 10:00
Good afternoon Elijah, your shipment has left. Arrival time after lunch. The driver will call you back later. Please organize prompt unloading. 09/09/2026 10:00
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 09/09/2026 10:10
Hello Scarlett, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 09/09/2026 10:13
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Virginia Beach 09/09/2026 10:20
Hello Mia, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 09/09/2026 10:23
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 09/09/2026 10:30
Hello Michael, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 09/09/2026 10:30
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 09/09/2026 10:40
John, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Minneapolis ? Contact Natalia, she will send the contract and invoice. 09/09/2026 10:41
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Detroit 09/09/2026 10:50
Hello Mia, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 09/09/2026 10:52
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- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR COATING TABLETS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
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- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
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- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
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- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
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- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COATING TABLETS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- FLOW-PACK PACKAGING MACHINES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
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