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GMP requirements: cleanliness of the device (it must not contaminate the substance); tightness of the device; ease of use. The following requirements are imposed on the processed material: during extrusion the wet mass should have plasticity, fluidity, self-binding properties, density (absence of voids); during spherization the extrudate should have mechanical rigidity, plasticity, absence of adhesion. Starch, talc and microcrystalline cellulose are added to prevent sticking;granules. In conclusion, it should be noted that: the granulation process is an important process in pharmaceutical production; the process of granule formation of the final product depends on the type of equipment used and many other factors; industrial and laboratory granulators are complex systems with a high degree of variability in performance.
Pharmaceutical Glossary
Technical specifications
The rotary-cylinder extruder consists of two cylinders: the first is a rotating cylinder with holes – the pelletizing cylinder, the second is a solid empty cylinder rotating towards the first. During the extrusion process, high pressure is created by the rotation of the two cylinders, resulting in a product of high density and a certain length. The advantages of the rotary-cylinder extruder are the high pressure created during the extrusion process, high density, a defined product length, and no stagnant zones. The disadvantage is the difficulty encountered in cleaning the equipment. The extruder is used for small outputs. Its design resembles that of a tablet machine. The Niro extruder is based on a unique technology of pushing and shearing the extrudate at low speed. This extruder is ideal for sensitive products that can be damaged in other, more intensive systems.
Additional information
The extruder has a wide range of screens of different sizes through which the product passes to optimize pellet diameter, surface characteristics and size distribution. This extruder can be operated in continuous and batch mode, with no stagnant zones or significant product delays. The extruder has a small footprint and is easy to clean, which is an important advantage. The choice of extruder can be made taking into account the following parameters: Principle requirements for the extruder: output; footprint; energy consumption. Methods of further processing or recycling. As recommendations, the following can be highlighted: if it is necessary to obtain homogeneous pellets dried in a fluidized bed, it is better to use a radial-press extruder; if it is necessary to obtain high-density extrudate with further sphericalization, it is more appropriate to use a rotary-cylindrical and press extruder. Scalability.
Order status tracking
HX-6 Plastic Tube Filling and Sealing Machine in Vatican City? Price delivery terms and conditions 19/05/2024 22:54
Abigail, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 19/05/2024 22:55
Can your technician come to Istanbul? We need technologist consultation and assistance. 19/05/2024 23:04
Joseph, We have already received your email. A technician between 16:00-18:00 will contact you. Don't worry. 19/05/2024 23:07
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled closer to evening to open the box and test. 19/05/2024 23:14
Carter, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 19/05/2024 23:17
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to San Antonio. Please confirm the delivery time. 19/05/2024 23:24
Good afternoon David, your shipment has left. Arrival time tomorrow until 12:30. The driver will call you back later. Please organize prompt unloading. 19/05/2024 23:25
HX-6 Plastic Tube Filling and Sealing Machine in Geneva? Price delivery terms and conditions 19/05/2024 23:34
Evelyn, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 19/05/2024 23:36
Tell me the NJ-120 automatic capsule machine went ? 19/05/2024 23:44
David, good afternoon. Yes, already tomorrow until 16:30 you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 19/05/2024 23:45
Good day, tell me need delivery in Houston to the settlement in the distance of 20 km. Can you organize this? 19/05/2024 23:54
Joseph, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 19/05/2024 23:57
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Cambridge ? 20/05/2024 00:04
Good afternoon, Layla! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 20/05/2024 00:05
Good day, delivery time of semi-automatic drum filling machine DF-10 to Skopun, will the courier call us? 20/05/2024 00:14
Lucas, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 20/05/2024 00:16
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 20/05/2024 00:24
Hello Aubrey, Transportation has advised that tomorrow until 17:30 driver will definitely deliver the box to your address. We apologize. 20/05/2024 00:27
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- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
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- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
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- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
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- AUTOMATIC CARTONING MACHINES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
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- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
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- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR LIQUID DOSING