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GMP requirements: cleanliness of the device (it must not contaminate the substance); tightness of the device; ease of use. The following requirements are imposed on the processed material: during extrusion the wet mass should have plasticity, fluidity, self-binding properties, density (absence of voids); during spherization the extrudate should have mechanical rigidity, plasticity, absence of adhesion. Starch, talc and microcrystalline cellulose are added to prevent sticking;granules. In conclusion, it should be noted that: the granulation process is an important process in pharmaceutical production; the process of granule formation of the final product depends on the type of equipment used and many other factors; industrial and laboratory granulators are complex systems with a high degree of variability in performance.
Pharmaceutical Glossary
Technical specifications
The rotary-cylinder extruder consists of two cylinders: the first is a rotating cylinder with holes – the pelletizing cylinder, the second is a solid empty cylinder rotating towards the first. During the extrusion process, high pressure is created by the rotation of the two cylinders, resulting in a product of high density and a certain length. The advantages of the rotary-cylinder extruder are the high pressure created during the extrusion process, high density, a defined product length, and no stagnant zones. The disadvantage is the difficulty encountered in cleaning the equipment. The extruder is used for small outputs. Its design resembles that of a tablet machine. The Niro extruder is based on a unique technology of pushing and shearing the extrudate at low speed. This extruder is ideal for sensitive products that can be damaged in other, more intensive systems.
Additional information
The extruder has a wide range of screens of different sizes through which the product passes to optimize pellet diameter, surface characteristics and size distribution. This extruder can be operated in continuous and batch mode, with no stagnant zones or significant product delays. The extruder has a small footprint and is easy to clean, which is an important advantage. The choice of extruder can be made taking into account the following parameters: Principle requirements for the extruder: output; footprint; energy consumption. Methods of further processing or recycling. As recommendations, the following can be highlighted: if it is necessary to obtain homogeneous pellets dried in a fluidized bed, it is better to use a radial-press extruder; if it is necessary to obtain high-density extrudate with further sphericalization, it is more appropriate to use a rotary-cylindrical and press extruder. Scalability.
Order status tracking
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 06/12/2025 05:31
Bella, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 06/12/2025 05:35
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Bruges, then I want to buy an automatic capsule machine model GN-28 06/12/2025 05:41
Good afternoon, Emilia! On the first question - the shipment will arrive in Bruges tomorrow until 18: 30. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 06/12/2025 05:42
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 06/12/2025 05:51
Hello Aiden, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 06/12/2025 05:53
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 06/12/2025 06:01
Hello Ruby, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Honolulu . 06/12/2025 06:01
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 06/12/2025 06:11
Sebastian, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 06/12/2025 06:11
You have to pay for delivery to Basel over and above the delivery amount in the contract ? 06/12/2025 06:21
Jackson, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 06/12/2025 06:21
Remember me? There's a delivery in the Luzern 06/12/2025 06:31
Matthew, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be tomorrow until 12:30 in Luzern . 06/12/2025 06:33
Can your technician come to Porto? We need technologist consultation and assistance. 06/12/2025 06:41
Mia, We have already received your email. A technician as stipulated in the contract will contact you. Don't worry. 06/12/2025 06:44
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Geneva, do you deliver to the terminal or to the actual address? 06/12/2025 06:51
Hello Aria, we ship all over Europe and the US including to Geneva . The price in the catalog includes any delivery our customer asks for. 06/12/2025 06:55
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 06/12/2025 07:01
Hello Lucas, We are on time, tomorrow until 16:30 a driver will contact you about unloading. 06/12/2025 07:02
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
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