СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

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СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

The evaporation surface and the thickness of the frozen material layer play a significant role in improving heat and mass transfer. Increasing the evaporation surface is achieved by increasing the dispersibility and specific surface area of the material. This can be accomplished by atomization and additional pulverization of the frozen product, which allows to obtain a product of high dispersibility. According to preliminary estimates, the cost of removing 1 kg of moisture by spray drying is 6 times less than freeze drying. At the same time, transportation costs are significantly lower, and the condition of the products is stable during long-term storage. However, research has shown that spray drying can only be used for microorganisms that can withstand high temperatures.

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Information updated: 07 / 09 / 2026
Available for
Production: 1 year на распылительную и сублимационную сушилки

Model: Combining spray drying and freeze drying

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Powders obtained by spray drying and combined spray and freeze drying have fundamental differences in particle shape. At the same time, the residual moisture content, surface properties of particles obtained by these two methods were similar. In both cases, the bulkiness was unsatisfactory. With the use of additives, an improvement in bulkiness was observed. In view of the above, it becomes obvious that there is a need to improve the energy efficiency of freeze dehydration technology, to develop new equipment, to create combined drying methods aimed at improving the quality of the obtained products. One of the tasks of improving the process of freeze drying (reducing the duration, energy consumption of the process) with simultaneous solution of the problems of quality of the obtained products can be solved by transition from drying in vacuum to drying at atmospheric pressure.

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Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

For most crops, however, freeze drying remains the only suitable method. Recent research by scientists has shown that spray drying and freeze drying can be combined in a single process to produce protein-rich dry powders, with the main advantage of obtaining a highly dispersed product.
The process was carried out in two stages: spraying of the solution in a metal container filled with liquid nitrogen under constant shaking; freeze drying in a Crist vacuum lyophilizer. At the same time, the quality of products dried by the combined method (degree of preservation of valuable properties, original structure, activity of ingredients) is not inferior to freeze-dried in vacuum.

Additional information

The products have better bulkiness and morphology, and there is no sintering of the top layer. The powders obtained in this way can be used for further encapsulation, pressing, epidermal administration, as well as for increasing the solubility of poorly soluble substances. Some scientists have also investigated the effect of the drying method on powder friability, which depends on a combination of different factors: size, shape, and surface properties of the particles. The comparison of spray and combined spray and freeze drying methods was carried out in terms of such indicators as: particle size and shape; moisture content, physical and chemical properties; the influence of additives and coatings on the friability of powders.

Order status tracking

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Joseph
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 11/09/2026 05:09

Roman Tsibulsky
Hello Joseph, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 11/09/2026 05:13

Violet
RZW-29 rotary tablet press in Cinque Terre. Regards, Violet. 11/09/2026 05:19

Roman Tsibulsky
Violet, Delivery will be made in the interval from 14:00-16:00 to Cinque Terre . Please have the movers ready. The weight of the equipment is heavy. 11/09/2026 05:21

Sophia
Can your technician come to Riga? We need technologist consultation and assistance. 11/09/2026 05:29

Roman Tsibulsky
Sophia, We have already received your email. A technician the day after tomorrow will contact you. Don't worry. 11/09/2026 05:32

Grace
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 11/09/2026 05:39

Roman Tsibulsky
Hello Grace, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 11/09/2026 05:39

Alexander
Good afternoon, I am hoping in the interval from 10:00-12:00 to get the UNIC 600A Tablet Press in Hum ! Please comment. 11/09/2026 05:49

Roman Tsibulsky
Good day, Alexander! Our manager has communicated with the delivery service, the equipment will be delivered to Hum at your address. Please let us know when you receive it. 11/09/2026 05:52

Layla
When is the SL-20 soft strip tablet packaging machine scheduled to be delivered to Salzburg ? 11/09/2026 05:59

Roman Tsibulsky
Hello Layla, Expect before lunch. Once received, please let us know. 11/09/2026 06:03

Jackson
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 11/09/2026 06:09

Roman Tsibulsky
Hello Jackson, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 11/09/2026 06:12

Gabriel
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 11/09/2026 06:19

Roman Tsibulsky
Hello Gabriel, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in York to 50 working ( not calendar) days. Action taken. 11/09/2026 06:22

Owen
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 11/09/2026 06:29

Roman Tsibulsky
Hello Owen, Our manager Natalia tomorrow until 13:30 will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Ljubljana in 15 days. 11/09/2026 06:32

Jackson
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 11/09/2026 06:39

Roman Tsibulsky
Jackson, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer closer to evening. We will report back immediately. 11/09/2026 06:42