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Subsequent atmospheric freeze drying was carried out in a boiling layer of adsorbent particles with a size of 80 microns. The rehydration properties of the products were not inferior to those obtained by vacuum freeze drying. Obtaining pharmaceutical protein-containing powders by freeze drying at atmospheric pressure in fluidized bed apparatuses opens wide prospects and advantages of their application. The dry product has high dispersibility, porosity, fast and complete solubility, good bulkiness and is ready for use. At the same time, dry powder can act as a semi-product and be used to produce tablets, capsules and other solid dosage forms, since its characteristics allow for mixing, pressing, granulation operations. The finished product due to its minimal particle size can be used for injectable, nasal, transdermal administration, has instant solubility and delivery properties of active components. Thus, the methods of atmospheric freeze drying are focused on obtaining products with particle size of micro- and nanosize with predetermined molecular structure and predetermined properties.
Pharmaceutical Glossary
Technical specifications
To cool the air to the required temperature, there is an additional cartridge located just before the conical part, which is filled with dry ice. The cylindrical part of the apparatus ends with a filter designed to catch and prevent fine particles from being carried away by the air stream. The filter is shaken periodically. Air, previously passed through the cartridge with dry ice, is supplied through the inlet opening of the conical part of the apparatus at a speed that provides a stable hydrodynamic regime. At the chamber outlet, the air is sequentially supplied for purification, heating and drying.
Additional information
Atmospheric freeze drying under conditions of convective heat supply allows: to intensify the process of moisture removal ten times; to significantly reduce the time of its implementation, while obtaining products that are not only not inferior in preserving useful properties to those freeze-dried in vacuum, but also superior to them in some qualitative characteristics; to organize the process not only in periodic, but also in semi-continuous and continuous modes. Scientists have demonstrated the suitability of atmospheric freeze drying for the treatment of coarse materials. However, due to the significant particle size (more than 1 cm) the process duration was an order of magnitude higher in comparison with vacuum freeze drying. To reduce the process time, part of the moisture was preliminarily removed by osmotic dehydration.
Order status tracking
Waiting for delivery to Cluj-Napoca of a TR-02 hard gelatin capsule polishing machine. What about it? 22/01/2025 02:11
Hello Liam, on your order we inform you that tomorrow until 14:30 the driver will contact you to clarify the time and place of unloading. 22/01/2025 02:13
To what address to send you samples of bottles and caps to send them to the factory ? Regards Brooklyn. 22/01/2025 02:21
Good day, Brooklyn We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 22/01/2025 02:25
Good day, I want between 16:00-18:00 to get FF-02 tablet and capsule filling machine in Vienna? 22/01/2025 02:31
Good afternoon, Liam! We have contacted the transportation company, your shipment is arriving in Vienna without delay. Please wait for a call from a representative of Business Lines. 22/01/2025 02:34
Good day, tell me need delivery in San Diego to the settlement in the distance of 20 km. Can you organize this? 22/01/2025 02:41
Charlotte, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 22/01/2025 02:42
Can your technician come to Mont St. Michel? We need technologist consultation and assistance. 22/01/2025 02:51
Aurora, We have already received your email. A technician in the interval from 14:00-16:00 will contact you. Don't worry. 22/01/2025 02:52
Please advise the delivery status of the order. Desktop ampoule sealing machine RF-01 delivery to Portland. Thank you. 22/01/2025 03:01
William, Checked delivery status , your shipment is in transit warehouse in Shanghai. Delivery to Portland is scheduled for tomorrow until 18: 30. Please notify us upon receipt. 22/01/2025 03:02
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Fresno. Please confirm the delivery time. 22/01/2025 03:11
Good afternoon Muhammad, your shipment has left. Arrival time tomorrow until 12:30. The driver will call you back later. Please organize prompt unloading. 22/01/2025 03:15
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Copenhagen, do you deliver to the terminal or to the actual address? 22/01/2025 03:21
Hello Alexander, we ship all over Europe and the US including to Copenhagen . The price in the catalog includes any delivery our customer asks for. 22/01/2025 03:22
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 22/01/2025 03:31
Hello Mason, Our manager Natalia as stipulated in the contract will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Debrecen in 15 days. 22/01/2025 03:33
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Brussels, then I want to buy an automatic capsule machine model GN-28 22/01/2025 03:41
Good afternoon, Aria! On the first question - the shipment will arrive in Brussels In the afternoon. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 22/01/2025 03:44
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- BOTTLE FILLING AND CAPPING EQUIPMENT
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR COATING TABLETS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- AUTOMATIC CARTONING MACHINES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING