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Equipment for wet granulation process

  • Granulation stage
  • Table production of pharmaceuticals
  • Production of sterile ointments
  • Drawing of the draining boiler
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  • preparation of soft dosage forms
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Equipment for wet granulation process

Granulate is produced by granulating wet material on special granulator machines. The principle of operation of granulators is that the material is rubbed by paddles, spring rollers or other devices through a perforated cylinder or mesh. In order to ensure the wiping process, the machine must be operated at optimum speed without overloading so that the moist mass passes freely through the cylinder or screen openings. If the mass is sufficiently moistened and moderately plastic, it will not stick to the holes and the process will proceed without difficulty. If the mass is viscous and glues the holes, the machine is overloaded and it is necessary to periodically turn off the motor and wash the drum blades.
The granulator contains a working chamber in which the wet material to be granulated is fed through a feed hopper.

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  • Information updated : 10 / 11 / 2024
  • In stock
  • Manufacturer : 1 year for Equipment for wet granulation process

Model: Wet granulation process

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Another apparatus design for combining mixing and pelletizing operations is the centrifugal mixer-granulator. Pelletizing liquid enters through the nozzle and spreads on the surface of the rotor. Bulk component through the spigot falls on the layer of liquid component and under the action of centrifugal forces is embedded in it. The ready mixture, reaching the cone 3, under the action of centrifugal forces flows through the holes, dispersed and captured by the flow of air coming through the spigots from bottom to top. The obtained granules settle in the conical part of the granulator, and the air is removed from the apparatus through the grid. Pellet size depends on the rotor operation mode, air head and perforation geometry of the cone. The disadvantages are the complexity of the shaft design and difficult cleaning of the granulator.

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Technical specifications

Screws are mounted on two parallel shafts in the chamber. The screws move and rub the material through a perforated plate forming the bottom of the working chamber. In the rotary transfer pelletizer, pellets are formed by pressing the product in the space between the “fingers” of the rollers, which rotate towards each other. The length of the product is controlled due to the design of the rolls. The advantages of this pelletizer are the high pressing speed and the controlled product length. The disadvantage is the low output. In the OYSTAR Huttlin, pellets are formed by centrifugal force generated by the rotation of the blades. Pelletizing liquid is fed through special nozzles located in two places of the machine.

Additional information

The granulate is removed from the machine through a special valve. The machine is equipped with a filter to catch small particles of material. Mixer-granulators. Usually the operations of mixing and uniform moistening of the powdered mixture with different granulating solutions are combined and carried out in one mixer. Mixing is ensured by vigorous forced circular mixing of particles and pushing them against each other. The mixing process to obtain a homogeneous mixture lasts 3-5 min. Then granulating liquid is fed into the mixer to the premixed powder and the mixture is mixed for another 3-10 min. After the granulation process is completed, the discharge valve is opened and the finished product is discharged by slowly rotating the scraper.

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