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СATALOGUE / EQUIPMENT WITH REVIEWS / PHARMA / LIQUID DISPENSER / Dosing (filling) with screw and vacuum dosing units

Dosing (filling) with screw and vacuum dosing units

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СATALOGUE / EQUIPMENT WITH REVIEWS / PHARMA / LIQUID DISPENSER / Dosing (filling) with screw and vacuum dosing units

Dosing (filling) with screw and vacuum dosing units

Dosing (filling) of powders is carried out with the help of special dosers, mainly screw and vacuum dosers working on the volumetric principle. Volumetric dispensers are simple in design, uncomplicated in operation, provide productivity up to 300 doses per minute. With decreasing medecine dose and increasing dosing speed, the error increases. Use special dispensers designed for volumetric dosing of bulk medecines in doses from 0.1 to 2 g.
Based on GF requirements, deviations in the mass of powders should not exceed certain values. Operating principle: The powder is loaded into the hopper. With the help of a regulator it is fed by a guide agitator through a throttle valve downwards into the feed hopper, in which the powder level is maintained. The dosing process is carried out into the prepared bottle by turning the vertical dosing screw. Operating principle: The powder to be dosed is fed into the filling hopper. The agitators, rotating respectively around the vertical and horizontal axes, ensure uniform distribution of the powder in the filling chamber.

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  • Information updated : 07 / 07 / 2024
  • In stock
  • Manufacturer : 1 year for Dosing (filling) with screw and vacuum dosing units

Model: Dosing (filling) with screw and vacuum dosing units

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However, it is not only the dosing accuracy that is decisive, but also continuous monitoring. Bosch has developed the IPK (in-process monitoring) system, which continuously monitors the filling powder mass and automatically adjusts the dispensing volume based on the weighing results. The same control conditions at any time are achieved by withdrawing the vials several at a time. If any of the doses deviate from the permissible parameters, the vial is discarded and the system automatically switches to one hundred percent in-process control. Once the dosage is corrected, the system automatically switches back to production mode. Each dispenser is monitored separately and all filling data is recorded. The market success of the new machines is not only due to the reliable dosing system and precise transport, but also to the user-friendly automation and visualization scheme. The mobile display can be customized for any operator. Since the production process is always highly dependent on product and dosing, all lines are equipped with programmable controllers. The operator is free to set production parameters such as vial format, dosing volume or Multiple Dosing according to product-specific requirements.

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Technical specifications

The rotor closing the bottom of the filling chamber has eight dosing holes. From the center of the wheel, dosing pistons, which determine the filling volume, are threaded into these holes. The rotor is periodically rotated by 1/8 of its volume after each cycle, the dosing holes are set above the filling chamber, and the powder is sucked into the holes under vacuum. After two cycles, the outer surface of the filling wheel is cleaned with a doctor and the excess powder is sucked off. Two further cycles bring the rotor into alignment with the neck opening of the prepared vial. The powder is discharged into the bottle by a short pulse of compressed air. Bosch is developing a new generation of sterile powder dispensing machines with a key feature in the dosing module. The machine’s dust-tight protection allows air conditioning (temperature and humidity control) in the dosing and capping areas. Due to its compactness, the machine can be equipped with an isolator.

Additional information

The central unit of AFG machines is a dosing unit using the vacuum and compressed air principle. With this dosing principle, the widest range of powders can be processed without dust formation and with great precision. Using vacuum, the powder is sucked into the dosing chamber and then blown back into the vial using sterile compressed air. After each dosing, the chamber is cleaned with sterile compressed air. Like all other parts of the machine in contact with the product, the dosing wheel is very easy to sterilize. Using a patented system, the dosing wheel can be replaced directly during the production of a single batch with complete sterility and without spilling powder from the feed hopper. In the feed hopper, the powder is stirred continuously by means of an agitator. The dosing accuracy depends on the filling volume and the properties of the powder. With the vacuum dosing method it is 1.5 % of the dosing volume. Machine for dispensing sterile powders. The dosing accuracy with the vacuum method is 2-3 times higher than with other technologies such as screw dosing.

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