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However, it is not only the dosing accuracy that is decisive, but also continuous monitoring. Bosch has developed the IPK (in-process monitoring) system, which continuously monitors the filling powder mass and automatically adjusts the dispensing volume based on the weighing results. The same control conditions at any time are achieved by withdrawing the vials several at a time. If any of the doses deviate from the permissible parameters, the vial is discarded and the system automatically switches to one hundred percent in-process control. Once the dosage is corrected, the system automatically switches back to production mode. Each dispenser is monitored separately and all filling data is recorded. The market success of the new machines is not only due to the reliable dosing system and precise transport, but also to the user-friendly automation and visualization scheme. The mobile display can be customized for any operator. Since the production process is always highly dependent on product and dosing, all lines are equipped with programmable controllers. The operator is free to set production parameters such as vial format, dosing volume or Multiple Dosing according to product-specific requirements.
Pharmaceutical Glossary
Technical specifications
The rotor closing the bottom of the filling chamber has eight dosing holes. From the center of the wheel, dosing pistons, which determine the filling volume, are threaded into these holes. The rotor is periodically rotated by 1/8 of its volume after each cycle, the dosing holes are set above the filling chamber, and the powder is sucked into the holes under vacuum. After two cycles, the outer surface of the filling wheel is cleaned with a doctor and the excess powder is sucked off. Two further cycles bring the rotor into alignment with the neck opening of the prepared vial. The powder is discharged into the bottle by a short pulse of compressed air. Bosch is developing a new generation of sterile powder dispensing machines with a key feature in the dosing module. The machine’s dust-tight protection allows air conditioning (temperature and humidity control) in the dosing and capping areas. Due to its compactness, the machine can be equipped with an isolator.
Additional information
The central unit of AFG machines is a dosing unit using the vacuum and compressed air principle. With this dosing principle, the widest range of powders can be processed without dust formation and with great precision. Using vacuum, the powder is sucked into the dosing chamber and then blown back into the vial using sterile compressed air. After each dosing, the chamber is cleaned with sterile compressed air. Like all other parts of the machine in contact with the product, the dosing wheel is very easy to sterilize. Using a patented system, the dosing wheel can be replaced directly during the production of a single batch with complete sterility and without spilling powder from the feed hopper. In the feed hopper, the powder is stirred continuously by means of an agitator. The dosing accuracy depends on the filling volume and the properties of the powder. With the vacuum dosing method it is 1.5 % of the dosing volume. Machine for dispensing sterile powders. The dosing accuracy with the vacuum method is 2-3 times higher than with other technologies such as screw dosing.
Order status tracking
I've been calling your office since this morning, and no one's picking up the phone. 24/10/2024 02:23
Good afternoon, Benjamin! The office will be open from 9:00 GMT. We'll be in touch. 24/10/2024 02:25
You have to pay for delivery to Figueres over and above the delivery amount in the contract ? 24/10/2024 02:33
Samuel, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 24/10/2024 02:35
Good day, delivery time of semi-automatic drum filling machine DF-10 to Leicester, will the courier call us? 24/10/2024 02:43
Ethan, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 24/10/2024 02:46
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 24/10/2024 02:53
Good day, Wyatt! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 24/10/2024 02:53
Remember me? There's a delivery in the London 24/10/2024 03:03
James, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be as agreed in London . 24/10/2024 03:06
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Santorini, do you deliver to the terminal or to the actual address? 24/10/2024 03:13
Hello Emma, we deliver all over USA including to Santorini . The price in the catalog includes any delivery our customer asks for. 24/10/2024 03:14
In Mostar ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 24/10/2024 03:23
Good afternoon, Aurora! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 24/10/2024 03:23
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 24/10/2024 03:33
Hello Evelyn, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Las Vegas . 24/10/2024 03:36
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Santorini, do you deliver to the terminal or to the actual address? 24/10/2024 03:43
Hello Maya, we deliver all over USA including to Santorini . The price in the catalog includes any delivery our customer asks for. 24/10/2024 03:44
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 24/10/2024 03:53
Hello Chloe, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Miami . 24/10/2024 03:53
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC CARTONING MACHINES
- FLOW-PACK PACKAGING MACHINES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS