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The most common combinations are the combination of a wet granulator-mixer with a spheronizer and an extruder with a spheronizer. Fluidized bed pelletizing. Pellets can be produced using a rotary insert in.a fluidized bed. The powder is mixed and moistened, the solvent or binder is fed tangentially. The powder layer is driven in a circular motion by the rotor insert. Process air, which is supplied through an adjustable gap at the edges of the rotor insert, drives the powder bed in a spiral motion. Agglomerates are formed which, due to the rotation of the rotor insert, are rolled into dense pellets with a regular spherical shape. The number of rotor revolutions has a direct influence on the density and size of the pellets. Drying of the wet pellets takes place either directly in the rotor during the drying phase at an elevated supply air temperature or in a fluidized bed dryer. Pellets are produced directly and very quickly from powder with the addition of a binder or solvent. The resulting pellets or pellets have a high density (comparable to the density of pellets produced in vertical pelletizers). If necessary, high-solid content shells are obtained by coating.
Pharmaceutical Glossary
Technical specifications
The particle size distribution of the resulting pellets is within a wide range of sizes. Pelletizing by rolling is the process of giving a spherical shape to extrudate after the extrusion process or to wet pellets after the wet granulation process. The spherical shaped pellets provide good stable friability and pellets with minimal mass variation are obtained. For example, in the study of granulates of calcium biphosphate, magnesium hydroxide and sulfadimezine prepared by wet granulation followed by rolling, it was found that their bulkiness increased by 40-100%. Rolling of wet pellets or extrudate is carried out on equipment called spheronizer. The principle of operation of a spheronizer is as follows: in the first stage, the material is compacted. With the help of a rotor-transfer granulator pellets are formed, which in the second stage are rolled in the spheronizer to a spherical shape and removed from the apparatus. In the presented GEA spheronizer, the plate is covered with smooth recesses. The plate is rotating and is tightly adhered to the walls of the apparatus. In this way, pellets with a good spherical shape are formed and a good particle size distribution is achieved.
Additional information
The granulate or extrudate is rolled to a spherical shape under the action of centrifugal and frictional forces. This design of the spheronizer solves the problem of material edge breakage and the appearance of unwanted small particles. Optimization of the process is achieved by selecting the rotation cycle time, plate speed, product loading and controlling the air flow around the periphery of the rotating plate. In the Glatt spheronizer, wet pelletized products or pre-formed extrudates are fed onto a rotating disk for pelletizing. The rotation of the disk, the flow of incoming product and a jet of air supplied through a slit in the side wall create an orderly product movement in a spiral path at the vessel wall. Due to intensive rolling, the surface of the particles is smoothed to form pellets. The dust particles generated in this process are captured again by the resulting pellets directly in the process. To increase the throughput capacity of the equipment in batch operation, several spheronizers are combined in a cascade. The cascade principle is also used to produce pellets with a laminated structure. The structure of the pellets is determined by the granulation process that takes place earlier in the process chain.
Order status tracking
Rotary tablet press RZK-25 I want to order with delivery to Berlin 07/01/2026 05:13
Good day, Stella We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 07/01/2026 05:15
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled tomorrow by lunchtime to open the box and test. 07/01/2026 05:23
Mia, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 07/01/2026 05:26
For shipping to Cinque Terre do you have to pay anything extra ? 07/01/2026 05:33
Good day Benjamin, In our catalog, all prices are inclusive of shipping to the customer's door. Delivery to Cinque Terre is included. 07/01/2026 05:34
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Cinque Terre, do you deliver to the terminal or to the actual address? 07/01/2026 05:43
Hello Elijah, we ship all over Europe and the US including to Cinque Terre . The price in the catalog includes any delivery our customer asks for. 07/01/2026 05:44
HX-6 Plastic Tube Filling and Sealing Machine in Istanbul? Price delivery terms and conditions 07/01/2026 05:53
Abigail, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 07/01/2026 05:55
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 07/01/2026 06:03
Bella, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer between 12:00-14:00. We will report back immediately. 07/01/2026 06:04
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 07/01/2026 06:13
Good afternoon, Benjamin! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 07/01/2026 06:15
In Valletta ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 07/01/2026 06:23
Good afternoon, Zoey! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 07/01/2026 06:25
Good afternoon, I am hoping tomorrow until 14:30 to get the UNIC 600A Tablet Press in Basel ! Please comment. 07/01/2026 06:33
Good day, Elijah! Our manager has communicated with the delivery service, the equipment will be delivered to Basel at your address. Please let us know when you receive it. 07/01/2026 06:37
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 07/01/2026 06:43
Ava, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 07/01/2026 06:44
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR COATING TABLETS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- FLOW-PACK PACKAGING MACHINES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- PERISTALTIC PUMPS DISPENSERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
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