СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Standardization of suppositories in the pharmaceutical industry

Standardization of suppositories in the pharmaceutical industry

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Standardization of suppositories in the pharmaceutical industry

Standardization of suppositories in the pharmaceutical industry

All manufactured suppositories must meet the requirements of the State Pharmacopoeia XI: Suppositories must have a homogeneous mass. Homogeneity of suppository is checked visually on a longitudinal slice for the presence or absence of inclusions, pieces” of the basis, particles of different colors, other inclusions, while the presence of air rod is allowed. Deviations in the mass of suppositories are allowed within 5%. Suppositories should have the correct uniform shape. In suppositories, the drug substances must be accurately dosed. The suppositories must have a hardness that makes them easy to use.

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Information updated : 08 / 02 / 2026
In stock
Manufacturer : 1 year for Standardization of suppositories in the pharmaceutical industry

Model: Standardization of suppositories in the pharmaceutical industry

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Automatic suppository packaging machine HYZ-01

Horizontal automatic wet alcohol wipes packaging machine LB-305

Tablet coating machine BG-40

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The release of drugs from hydrophobic bases is slower.
When making suppositories, it should be remembered that the drug substances introduced into the composition of these dosage forms in the form of aqueous solutions, absorbed much easier and faster have a local effect than the drug substances introduced in dry form. In terms of microbiological purity of preparations for rectal administration are classified by the State Pharmacopoeia to category IIIA, ie in 1 g or 1 ml of the drug should contain no more than 1000 aerobic bacteria and 100 fungi in the absence of Escherichia coli.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

All suppositories (especially rectal and urethral) must have sufficient hardness to overcome the resistance of tissues and sphincters, otherwise the suppositories are deformed and their use becomes impossible. The melting point determined for lipophilic suppositories should not exceed 37 °C. Moreover, it is necessary that their melting occurred in a short temperature range (1-2 ° C). If the definition of melting temperature causes difficulties, then set the time of full deformation, which should be no less than 3 and no more than 15 min. For suppositories made on hydrophilic bases, determine the time of dissolution in water, which should not exceed 1 h.

Additional information

The liquid mass formed after melting or dissolution of suppositories should spontaneously spread over the mucous membrane, forming a uniform layer. This condition is necessary to ensure close contact of the drug substance with tissues and its proper absorption. Suppositories should easily release the drug substances included in them. This quality depends both on the properties of the base used for the preparation of suppositories, and on the method of introduction of drugs into the base. Hydrophilic bases (except polyethylene oxides) easily release active substances, as they are able to dissolve in the secretions of mucous membranes.

Order status tracking

Roman Tsibulsky +79853643808 now online

William
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 18/02/2026 10:57

Roman Tsibulsky
Hello William, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 18/02/2026 10:59

Sofia
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 18/02/2026 11:07

Roman Tsibulsky
Sofia, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer the day after tomorrow. We will report back immediately. 18/02/2026 11:09

Lucas
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Santa Ana. Please confirm the delivery time. 18/02/2026 11:17

Roman Tsibulsky
Good afternoon Lucas, your shipment has left. Arrival time tomorrow until 15:30. The driver will call you back later. Please organize prompt unloading. 18/02/2026 11:20

Leah
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Albuquerque. 18/02/2026 11:27

Roman Tsibulsky
Good day Leah, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Albuquerque is included in the price. 18/02/2026 11:29

Ava
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Braila ? 18/02/2026 11:37

Roman Tsibulsky
Good afternoon, Ava! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 18/02/2026 11:38

Scarlett
We're from New Jersey, we paid for the equipment on your invoice yesterday. Has the payment been received? How long will it take to deliver to us? 18/02/2026 11:47

Roman Tsibulsky
Scarlett, hello. Payment is credited to our settlement account. Term of manufacture of your equipment by the factory 20 working days, delivery from the factory to our warehouse in the USA 1 month, delivery from the warehouse in Pittsburgh 15 calendar days. 18/02/2026 11:50

Mia
In Hum ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 18/02/2026 11:57

Roman Tsibulsky
Good afternoon, Mia! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 18/02/2026 11:58

Grace
Mixer with paddle for powders CX-100 what is the exact packing size ? 18/02/2026 12:07

Roman Tsibulsky
Grace, Hello! Packing dimensions 1200x640x1000 mm, packing weight 250 kg. Please let me know when you receive the shipment. 18/02/2026 12:09

Owen
I've been calling your office since this morning, and no one's picking up the phone. 18/02/2026 12:17

Roman Tsibulsky
Good afternoon, Owen! The office will be open from 9:00 GMT. We'll be in touch. 18/02/2026 12:21

Amelia
In Couresaire ITA-01 tablet and capsule counter, RZ-9 rotary tablet press and manual capsule filling machine. Help when we get it ? 18/02/2026 12:27

Roman Tsibulsky
Good afternoon, Amelia! We have received from the factories photos of the equipment after packing. Natalia will forward the photos to you. Delivery time to you is 45-50 days. 18/02/2026 12:29