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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Ingredients of gelatin capsules

Ingredients of gelatin capsules

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Ingredients of gelatin capsules

Ingredients of gelatin capsules

Soft gelatin capsules are a dosage form of a soft dosage form that consists of a shell and a medicinal product encapsulated in it. Capsules can have different shapes (round, oval, oblong, etc.), different size, color and consistency of the filler. To obtain capsule shells, various film-forming high molecular weight substances are used, which are capable of forming elastic films and are characterized by a certain mechanical strength.
The modern pharmaceutical industry most widely uses gelatin as a forming material, so most capsules* produced in the industry are gelatin capsules.

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  • Information updated : 28 / 12 / 2025
  • In stock
  • Manufacturer : 1 year for Ingredients of gelatin capsules

Model: Gelatin capsule composition

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Diluents are most often used to give the capsule filler the required optimal volume. For soft gelatin capsules as an indifferent diluent, vegetable oils, polyethylene oxide mixtures, silicone oils and complex component compositions including, in addition to the above, glycerin, propylene glycol, tween-80, etc., are used. If necessary, other additives may be added to the fillers.

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Technical specifications

To obtain a soft gelatin capsule shell, a gelatin mass is prepared, the composition of which, in addition to gelatin, includes various auxiliary ingredients. They allow to improve the structural and mechanical properties of the capsule shell, protect it from moisture, protect it from microbial contamination, give it the desired color and odor, etc. The properties of gelatin, as well as the characteristics of the excipients included in the gelatin capsule shell, are described in detail in Section 4.12 on the manufacture of hard gelatin capsules. Drugs encapsulated in the capsule shell are called excipients.

Additional information

Soft gelatin capsules contain easy-flowing or paste-like fillers such as oils, fats, vitamins, oil or other non-aqueous solutions, suspensions, paste-, ointment- or gel-like substances. Some foreign companies and researchers have conducted work on the manufacture of soft gelatin capsules containing hard filler (powders or mixtures thereof), but these developments have not received practical distribution, having turned out to be irrational. In addition to pharmacologically active substance, in” the composition of capsule filler in order to give it the necessary technological characteristics and biopharmaceutical properties are introduced auxiliary ingredients, which should be biologically indifferent.

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