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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Incorporation of medicine substances into the ointment base

Incorporation of medicine substances into the ointment base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Incorporation of medicine substances into the ointment base

Incorporation of medicine substances into the ointment base

The next step in the production of ointments is the introduction of medicine into the ointment base. In this case, attention should be paid to the following factors: the degree of dispersibility of medicine, their uniform distribution throughout the mass of the base, the method of introduction of medicine into the base, time, speed and order of mixing components, temperature regime, etc. Medicinal substances are introduced into ointments taking into account their quantity and physicochemical properties. They are of three types: soluble in the base, easily soluble in water, insoluble neither in the base nor in water.

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  • Information updated : 28 / 04 / 2024
  • In stock
  • Manufacturer : 1 year for Incorporation of medicine substances into the ointment base

Model: Ointment production

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The lid of the reactor vessel is raised and lowered by means of a crosshead and hydraulic supports. Inside the reactor vessel there is an anchor-type agitator with blades along the vessel profile covering the entire useful surface. The agitator with blades rotates in the opposite direction to the rotation of the anchor agitator. The agitators are rotated by coaxial shafts using hydraulic motors. A turbine agitator rotated by an electric motor is also mounted in the reactor vessel. The presence of three stirrers provides good mixing and grinding of ointment components. The apparatus is discharged through a ball valve, the reactor body has a jacket to which hot water with temperature up to 95 ° C or cold water with temperature up to 12 ° C is supplied. The reactor has remote control.

Pharmaceutical Glossary

Articles  — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.
Blog Business Business plan Buy a business Classification of ointments Commerce Company Cream packaging Cream production Diphilic bases Equipment catalog Homogenization Hydrophobic bases Innovation Investments Medicinal substances Novelty Ointment packaging Ointment production Production Production organization sieving Startup Storage of ointments

Technical specifications

The type of medicine substance determines whether it can be used to produce a particular type of ointment. Introduction of medicine substances into the base is preceded by their preparation, during which the medicine substances are crushed, sieved through a sieve with a certain diameter of holes (if they are included in the ointment type of suspension) or dissolved in water or a suitable component of the ointment base (if it is an ointment-emulsion or ointment-solution). The addition of solid medicine substances or their solutions to the base is carried out under constant stirring in double-roll mixers or in steam-jacketed or electrically heated reactors.

Additional information

Powerful agitators (anchor, planetary, propeller or frame agitators) capable of mixing in highly viscous media throughout the entire volume at various temperatures are used. Steam jacketed reactor is designed for mixing thick components with viscosity up to 200 Ns/cm2. The reactor has a body with a hemispherical bottom. The reactor body is closed with a convex lid, in which the feeding funnel, sight glass, valves, nozzles and connections for the introduction of various substances are mounted.

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