СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

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СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

The evaporation surface and the thickness of the frozen material layer play a significant role in improving heat and mass transfer. Increasing the evaporation surface is achieved by increasing the dispersibility and specific surface area of the material. This can be accomplished by atomization and additional pulverization of the frozen product, which allows to obtain a product of high dispersibility. According to preliminary estimates, the cost of removing 1 kg of moisture by spray drying is 6 times less than freeze drying. At the same time, transportation costs are significantly lower, and the condition of the products is stable during long-term storage. However, research has shown that spray drying can only be used for microorganisms that can withstand high temperatures.

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Information updated : 07 / 01 / 2026
In stock
Manufacturer : 1 year for Combining spray drying and freeze drying

Model: Combining spray drying and freeze drying

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Powders obtained by spray drying and combined spray and freeze drying have fundamental differences in particle shape. At the same time, the residual moisture content, surface properties of particles obtained by these two methods were similar. In both cases, the bulkiness was unsatisfactory. With the use of additives, an improvement in bulkiness was observed. In view of the above, it becomes obvious that there is a need to improve the energy efficiency of freeze dehydration technology, to develop new equipment, to create combined drying methods aimed at improving the quality of the obtained products. One of the tasks of improving the process of freeze drying (reducing the duration, energy consumption of the process) with simultaneous solution of the problems of quality of the obtained products can be solved by transition from drying in vacuum to drying at atmospheric pressure.

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Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

For most crops, however, freeze drying remains the only suitable method. Recent research by scientists has shown that spray drying and freeze drying can be combined in a single process to produce protein-rich dry powders, with the main advantage of obtaining a highly dispersed product.
The process was carried out in two stages: spraying of the solution in a metal container filled with liquid nitrogen under constant shaking; freeze drying in a Crist vacuum lyophilizer. At the same time, the quality of products dried by the combined method (degree of preservation of valuable properties, original structure, activity of ingredients) is not inferior to freeze-dried in vacuum.

Additional information

The products have better bulkiness and morphology, and there is no sintering of the top layer. The powders obtained in this way can be used for further encapsulation, pressing, epidermal administration, as well as for increasing the solubility of poorly soluble substances. Some scientists have also investigated the effect of the drying method on powder friability, which depends on a combination of different factors: size, shape, and surface properties of the particles. The comparison of spray and combined spray and freeze drying methods was carried out in terms of such indicators as: particle size and shape; moisture content, physical and chemical properties; the influence of additives and coatings on the friability of powders.

Order status tracking

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William
Can your technician come to York? We need technologist consultation and assistance. 10/01/2026 22:14

Roman Tsibulsky
William, We have already received your email. A technician tomorrow until 17:30 will contact you. Don't worry. 10/01/2026 22:17

Riley
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 10/01/2026 22:24

Roman Tsibulsky
Good afternoon, Riley! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 10/01/2026 22:26

Evelyn
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 10/01/2026 22:34

Roman Tsibulsky
Hello Evelyn, The shipment has arrived at the customs terminal, tomorrow until 16:30 is scheduled to be transferred to the transportation company. 10/01/2026 22:37

Brooklyn
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 10/01/2026 22:44

Roman Tsibulsky
Brooklyn, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 10/01/2026 22:46

Penelope
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 10/01/2026 22:54

Roman Tsibulsky
Hello Penelope, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 10/01/2026 22:55

Oliver
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Nashville. Please confirm the delivery time. 10/01/2026 23:04

Roman Tsibulsky
Good afternoon Oliver, your shipment has left. Arrival time tomorrow until 18: 30. The driver will call you back later. Please organize prompt unloading. 10/01/2026 23:05

Emilia
Vacuum lyophilic freeze dryer LG-30, can we get faster than the contract ? 10/01/2026 23:14

Roman Tsibulsky
Hello Emilia, Shipments go through several time stages. Manufacturing, delivery from the factory to the warehouse in Beijing or Shanghai, waiting for batch collection, customs clearance and delivery. It's hard to predict. 10/01/2026 23:17

Benjamin
The BB-152 liquid filling machine arrived from you today, remember us ? Where's the paperwork? 10/01/2026 23:24

Roman Tsibulsky
{The original shipping documents will be delivered to London tomorrow until 18: 30. Please send the signed copies to us. 10/01/2026 23:25

Isabella
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 10/01/2026 23:34

Roman Tsibulsky
Hello Isabella, The shipment has arrived at the customs terminal, tomorrow until 16:30 is scheduled to be transferred to the transportation company. 10/01/2026 23:35

Muhammad
Automatic blister packaging machine for PVC+cardboard LW-35 with delivery to Denver. We want to track the delivery status. 10/01/2026 23:44

Roman Tsibulsky
Muhammad, hello. The shipment has already arrived. Now it is in the warehouse of the transportation company. Your manager will contact you to clarify the time of delivery to your city. 10/01/2026 23:47