СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

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СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

The evaporation surface and the thickness of the frozen material layer play a significant role in improving heat and mass transfer. Increasing the evaporation surface is achieved by increasing the dispersibility and specific surface area of the material. This can be accomplished by atomization and additional pulverization of the frozen product, which allows to obtain a product of high dispersibility. According to preliminary estimates, the cost of removing 1 kg of moisture by spray drying is 6 times less than freeze drying. At the same time, transportation costs are significantly lower, and the condition of the products is stable during long-term storage. However, research has shown that spray drying can only be used for microorganisms that can withstand high temperatures.

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Information updated: 10 / 08 / 2026
Available for
Production: 1 year на распылительную и сублимационную сушилки

Model: Combining spray drying and freeze drying

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Powders obtained by spray drying and combined spray and freeze drying have fundamental differences in particle shape. At the same time, the residual moisture content, surface properties of particles obtained by these two methods were similar. In both cases, the bulkiness was unsatisfactory. With the use of additives, an improvement in bulkiness was observed. In view of the above, it becomes obvious that there is a need to improve the energy efficiency of freeze dehydration technology, to develop new equipment, to create combined drying methods aimed at improving the quality of the obtained products. One of the tasks of improving the process of freeze drying (reducing the duration, energy consumption of the process) with simultaneous solution of the problems of quality of the obtained products can be solved by transition from drying in vacuum to drying at atmospheric pressure.

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Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

For most crops, however, freeze drying remains the only suitable method. Recent research by scientists has shown that spray drying and freeze drying can be combined in a single process to produce protein-rich dry powders, with the main advantage of obtaining a highly dispersed product.
The process was carried out in two stages: spraying of the solution in a metal container filled with liquid nitrogen under constant shaking; freeze drying in a Crist vacuum lyophilizer. At the same time, the quality of products dried by the combined method (degree of preservation of valuable properties, original structure, activity of ingredients) is not inferior to freeze-dried in vacuum.

Additional information

The products have better bulkiness and morphology, and there is no sintering of the top layer. The powders obtained in this way can be used for further encapsulation, pressing, epidermal administration, as well as for increasing the solubility of poorly soluble substances. Some scientists have also investigated the effect of the drying method on powder friability, which depends on a combination of different factors: size, shape, and surface properties of the particles. The comparison of spray and combined spray and freeze drying methods was carried out in terms of such indicators as: particle size and shape; moisture content, physical and chemical properties; the influence of additives and coatings on the friability of powders.

Order status tracking

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Mia
Good day , Electronic conveyor belt package weight detector DK-05 when will we receive in Athens ? 29/08/2026 23:36

Roman Tsibulsky
Hello Mia, your shipment is in the customs warehouse, between 12:00-14:00 your manager Natalia will contact you. 29/08/2026 23:40

Jackson
Roman hello, what about the automatic filling and sealing machine for sterile ampoules ABF-4D-1, invoice #101. 29/08/2026 23:46

Roman Tsibulsky
Good afternoon, Jackson! We are making a request to the manufacturer. Tomorrow we will send photos and video of testing to your e-mail. 29/08/2026 23:47

Samuel
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 29/08/2026 23:56

Roman Tsibulsky
Good day, Samuel! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 29/08/2026 23:59

Aiden
Good afternoon, please confirm that in the morning we will receive our shipment in Florence? Contact the transportation company. 30/08/2026 00:06

Roman Tsibulsky
Hello Aiden ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Florence in a few days. Please expect it. 30/08/2026 00:10

Samuel
Good afternoon, please confirm that between 16:00-18:00 we will receive our shipment in Santorini? Contact the transportation company. 30/08/2026 00:16

Roman Tsibulsky
Hello Samuel ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Santorini in a few days. Please expect it. 30/08/2026 00:20

James
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 30/08/2026 00:26

Roman Tsibulsky
Hello James, Our manager Natalia tomorrow until 12:30 will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Gerona in 15 days. 30/08/2026 00:29

Penelope
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 30/08/2026 00:36

Roman Tsibulsky
Hello Penelope, We are on time, as stipulated in the contract a driver will contact you about unloading. 30/08/2026 00:37

Savannah
Horizontal granulator for organic fertilizers JU-80, the price is up to date ? Delivery time to Riga? Urgent. 30/08/2026 00:46

Roman Tsibulsky
Savannah, Please read carefully the description of this model in our catalog. Prices are current. Timing 1-1.5 months. 30/08/2026 00:48

Andrew
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled in the interval from 10:00-12:00 to open the box and test. 30/08/2026 00:56

Roman Tsibulsky
Andrew, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 30/08/2026 00:58

Samuel
I've been calling your office since this morning, and no one's picking up the phone. 30/08/2026 01:06

Roman Tsibulsky
Good afternoon, Samuel! The office will be open from 9:00 GMT. We'll be in touch. 30/08/2026 01:10