.. Author Roman Tsibulsky | CATALOG OF PHARMACEUTICAL EQUIPMENT MINIPRESS.RU | MANUFACTURE AND SALE OF

Stages of preparation of raw materials for tablet production

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For most chemical and pharmaceutical preparations, the technology of tablet production consists of the following disparate operations of weighing the starting material, grinding, sieving, mixing, granulation, tableting (pressing), coating. Some of the listed operations in the manufacture of pharmaceuticals may be absent. Three common technological schemes for obtaining tablets are most common: using wet granulation,...

Force to push tablets out of the matrix

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To push the compressed tablet out of the matrix, it is required to expend force to overcome friction and adhesion between the side surface of the tablet and the wall of the matrix. Taking into account the magnitude of the ejection force, additives of antifriction (sliding or lubricating) substances are predicted. As an example, the...

Dry granulation of powders

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Dry granulation is a method in which a powdery material (a mixture of medicinal and auxiliary substances) is compacted to produce a granulate. Dry granulation is used in cases where wet granulation affects the stability and/or physico-chemical characteristics of the medicinal substance, as well as when the medicinal and auxiliary substances are poorly compressed after...

Ozone tunnel sterilization dryer ZXP-MG

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The ozone tunnel sterilization dryer ZXP-MG is used for drying and sterilization after washing plastic containers for eye drops, oral liquids in the pharmaceutical and food industries. The heating system and the ozonator of this machine can be controlled automatically and in a preset mode. The speed of the conveyor is regulated within a specified…

Suppository bases and their requirements

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From a physico-chemical point of view, suppositories are considered as dispersed systems consisting of a dispersion medium, represented by the basis of the Dispersed phase, in the role of which medicinal substances act. Depending on the properties of medicinal substances, dispersed systems of suppositories can be either homogeneous or heterogeneous. Homogeneous systems are formed when...

Modern capabilities of tablet presses

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Many companies producing pharmaceutical equipment are constantly working on improving the tablet presses and their components used. Recently, the company FETTE (Germany) has improved the rotary tablet press, using a segmented matrix disk instead of traditional matrices. Instead of 47 matrices and 47 screws, only 3 segments are used, which gives clear advantages, such as:...

Binders for wet granulation

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There are some requirements for the granulating liquid, one of them is that the granulating liquid should not dissolve the active substance. Water, an aqueous solution of ethanol, acetone and methylene chloride can be used as a granulating liquid. A wide range of substances are used as binding agents for wet granulation in modern pharmaceutical...

Fluidized bed dryer CJM-60

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Fluidized bed dryer dryer uses a stream of hot air to keep the pellets in a “suspended” state in the pseudo-liquefied layer and dry them quickly, the spent water evaporates with the air flow. This equipment is used in the production of medical herbal preparations, combined powders, granules, lumpy materials, chemical products, etc. Quick drying….

Tableting pressing in pharmaceutical production

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Tableting (pressing) is the process of forming tablets from granular or powdery material under pressure. In modern pharmaceutical production, tableting is carried out on special presses called tablet machines.

Standardization of suppositories in the pharmaceutical industry

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All manufactured suppositories must meet the requirements of the State Pharmacopoeia XI: Suppositories must have a homogeneous mass. The uniformity of the suppository is checked visually on the longitudinal section by the presence or absence of inclusions, pieces of the "base, particles of various colors, other inclusions; at the same time, the presence of an...

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