Vacuum lyophilic freeze dryer “RL-07”
Material: – European stainless steel ANSI 316L
Number of shelves: – customer’s choice 1/2/3/4/5/6
Shelf size: – 500mm(length)x270mm(width)x10mm(thickness)
Useful area of shelves: – 0,135/0,27/0,405/0,54/0,675/0,81 m2 (depending on the number of shelves).
Distance between shelves: – 312/156/100,6/73/56,4/45,3 mm
Temperature range: -70°C to +80°C
Shelf cooling rate: +20°C to -40°C 30 min (no load)
Shelf heating rate: +20°C to -40°C 60 min.
Temperature stability: – ±1°C
Front door (rectangular): – Polymethylmethacrylate (PMMA)
Door locking method: – Manual locking.
Condenser: – Independent
Condenser material: – European stainless steel ANSI 316L, with external coil.
Ice capacity in condenser: – 10 kg
Minimum temperature: – 85°C
Condenser cooling rate: +20°C to -40°C 30 min.
Defrosting mode: by hot vapors of refrigeration agent
Condenser chamber front door: – polymethyl methacrylate (PMMA)
Hydraulic station: BREVINI Placed under the chamber
Tank: 2 liters
Closing force: 0~1.0 bar (adjustable)
Pneumatic system: – not available
Circulation pump: WILO, Germany
Pump capacity: 93/67/46 revolutions/minute
Heat transfer medium: Silicone oil 2 cSt (low viscosity)
Heater: – 1 kW
Plate heat exchanger: ALFALAVAL, Sweden
Heating speed: – 1°C/min
Vacuum pump: – Edwards
Standard flow rate: – 17 m3/h
Maximum residual pressure in the chamber: – 1 Pa
Pumping out: from atm. to 10 Pa – 15 min.
Leakage rate: – 5×10-3 Pa.m3/sec.
Cooling method: – cascade cooling system
Minimum shelf temperature: -70°C
Minimum condenser temperature: -85°C
Refrigerant (without chlorofluorocarbon):
Main circuit: R-508B / auxiliary circuit: R-407C
Cooling: – by air
Compressor brand: – Bitzer
Number of compressors: – 2
Capacity: 4 hp.
PLC: SIEMENS manufacturer
Touch screen: SIEMENS
Size: 7 inches
Resolution: 800 x 480
Software: – from OEM
Electrical components: – SIEMENS & WEIDMULLER.
System design: – combined (use in clean room)
Size of lyophilizer: 1500mm(length)x620mm(width)x1990mm(height)
Voltage: – 380V
Power consumption: – 6kW
Ambient temperature during operation: – 5-25°C
Weight (approx.): 400 kg
Weight with packaging: 500 kg

The process of operation of this equipment consists of placing vials with liquid material into the freeze drying chamber and then obtaining dried powder. Pre-rinsed and dried glass penicillin vials are used, into which the material is poured. Then the vials are capped with special rubber stoppers having side slits in the part that enters the neck of the vial. Corking is made not to the end but by 50%, only to fix the rubber stopper in the neck of the bottle. Subsequently, the liquid is pumped out of the bottle through these slits by vacuum. In the final stage, after complete dehydration of the material is a complete closure of the plug with hydraulic movable shelves. Thus drying takes place in a vacuum environment, and then the material is finally packed in a vacuum. This allows (unlike other types of similar drying) to keep the material in vacuum for 1-2 years. After the bottles are vacuumized the chamber can be opened and automatic or semi-automatic fixing of the rubber stopper with an aluminum cap can be performed. The caps are put on the neck of the vial and sealed. According to the statements of the manufacturer of the equipment, with such technology it is possible to fully restore the viability of the material after dehydration when opening the vacuum packaging within 4-5 hours. Storage in a vacuum material is possible at a temperature not exceeding +36 degrees C. Since in the process of dehydration (water removal) the equipment dehydrates the material, the recovery takes place with distilled water. The removed water is frozen in the chamber, then drained after defrosting and it is possible to control how many ml came out of the dried product, in order to restore later exactly the same amount of water. This is an important point. According to the manufacturer’s statements not all materials can be turned into powder, some biological materials when dehydrated turn into a jelly-like substance, which is also recovered with distilled water. The manufacturer of the equipment has a large laboratory, which together with the experienced production can carry out any research of your material, get samples of products in dried form and packed in vacuum for further research by customers.