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Depending on the bulk density, the following powders are distinguished: very heavy, heavy, medium and light. Relative density is the ratio of the bulk density to the true density. Porosity is the relative volume of free space (pores, voids) between powder particles. The powder’s ability to compress under pressure depends on these volumetric characteristics. Compaction (compression) ratio is the ratio of the height of the powder layer in the matrix to the height of the resulting tablet. The compression ability of powdered preparations is influenced by the shape of particles, the ability of the latter to move and deform under pressure. Compaction factor is a significant technological factor.
The higher the compaction ratio, the more time is spent on pressing, while more effort is also spent on pushing the tablet out of the depth of the matrix channel.
Pharmaceutical Glossary
Technical specifications
This is due to the granulation technology of the wet material, which involves repeated mixing and powdering. The mixing and powdering process not only introduces a large number of fine particles into the mixture, but also pulverizes it.
Non-granulated powders are characterized by their polyfractional composition and complex shape. The average particle size of non-granulated powders is 30 to 120 microns.
As practice shows, for pharmaceutical production it is more indicative to characterize all significant fractions of the powder in order to make a conclusion about the possibility of its use in the technology of this or that medicine.
For example, with the help of conducted researches at JSC “Chemical-Pharmaceutical Combine “AKRIHIN” the fractional composition of substances used in production was determined by microscopy (particles smaller than 100 microns) and sieve analysis (particles larger than 100 microns). When using sieve analysis, the material under study is divided into fractions by sieving through a standard set of sieves for 5 min, and then the mass of each fraction and its percentage content are determined.
Additional information
The obtained data on the shape of powder particles and their fractional composition are included in the internal quality specifications of substances. This will allow manufacturing companies to control the quality of incoming raw materials. Bulk (volumetric) density is the mass of a unit volume of freely dispersed powdery material. Bulk density is determined quite simply and can be a convenient indicator of the properties of powders, since it is a complex characteristic depending on the shape, particle size distribution, density, humidity, dispersibility of powders, their specific surface. The bulk density value can be used to predict the volume of the matrix channel of the tablet machine (see section 4.9). The bulk density is determined by freely pouring the powder into a defined volume (e.g. measuring cup) and then weighing it to the nearest 0.01 g. It is believed that bulk density affects bulkiness and can characterize it. The results of studies show that the flowability of powder improves with increasing bulk density, but this cannot be said for the finest fractions, for which the relationship between bulk density and flowability may be broken due to a sharp increase in internal friction forces.
Order status tracking
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Sofia, do you deliver to the terminal or to the actual address? 22/07/2024 06:22
Hello Michael, we ship all over Europe and the US including to Sofia . The price in the catalog includes any delivery our customer asks for. 22/07/2024 06:24
You have to pay for delivery to Mariehamn over and above the delivery amount in the contract ? 22/07/2024 06:32
Brooklyn, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 22/07/2024 06:34
Good day , Electronic conveyor belt package weight detector DK-05 when will we receive in Athens ? 22/07/2024 06:42
Hello Brooklyn, your shipment is in the customs warehouse, in the interval from 10:00-12:00 your manager Natalia will contact you. 22/07/2024 06:45
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 22/07/2024 06:52
Good afternoon Noah, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. as stipulated in the contract we will get a reply from the manufacturer on the final time frame. 22/07/2024 06:54
RZW-29 rotary tablet press in Vatican City. Regards, Hannah. 22/07/2024 07:02
Hannah, Delivery will be made closer to evening to Vatican City . Please have the movers ready. The weight of the equipment is heavy. 22/07/2024 07:06
To what address to send you samples of bottles and caps to send them to the factory ? Regards Chloe. 22/07/2024 07:12
Good day, Chloe We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 22/07/2024 07:16
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 22/07/2024 07:22
Hello John, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 22/07/2024 07:25
Good day, tell me need delivery in Denver to the settlement in the distance of 20 km. Can you organize this? 22/07/2024 07:32
Liam, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 22/07/2024 07:35
Today we were promised delivery of a blister machine for MN-14 tablets and capsules, remember us ? No one's called us back. 22/07/2024 07:42
Hello Benjamin, Our manager Natalya tomorrow until 16:30 will dial the driver, also we ask you yourself to the transportation company. 22/07/2024 07:44
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 22/07/2024 07:52
Good day, Benjamin! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 22/07/2024 07:53
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR COATING TABLETS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- AUTOMATIC CARTONING MACHINES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES