СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Introduction of medicine substances into the suppository base

Introduction of medicine substances into the suppository base

There are three ways of introducing medicine into the suppository base, which are determined by the physical and chemical properties of the components: All water-soluble components are introduced in the form of aqueous solutions; fat-soluble substances are introduced in the form of fat solutions; substances insoluble in water and fat are introduced in the form of suspensions of powders melted into the bases. The resulting solutions or suspensions are called concentrates.

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Information updated: 28 / 06 / 2026
Available for
Production: 1 year на оборудование для введения в суппозиторную основу лекарственных веществ

Model: Suppository base

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Our service and customer service

The ready concentrate is pumped by a pump (through a hose with a capron sieve) into a reactor with a suppository base. Preparation of suppository mass is carried out with constant stirring and heating to a temperature of 45-50 ° C. At the end of the process, the product is analyzed for homogeneity of mixing of components, check the time of complete deformation, as well as the solidification and melting temperature of the mass. If positive results are obtained, the suppository mass is submitted for pouring into molds.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

At the stage of medicine preparation, water-soluble components are dissolved in water heated to 45 ° C, and fat-soluble components are dissolved in a portion of the melted fat base. The resulting concentrates are filtered and then mixed with the remaining base. Substances insoluble in water and base, introduced in the form of suspension as follows: pre-crushed medicine substances mixed in a reactor with an equal or one and a half times the amount of base, heated to a temperature of 40-50 ° C.

Additional information

The obtained concentrate is cooled and milled in colloid mills. For treatment of thermolabile substances three-roll masheters are used. In addition, to obtain high-quality suspensions can be used rotary-pulsation devices, rotary-tooth pumps and other equipment. To obtain the required degree of dispersibility of the medicine substance introduced into the base on the type of suspension, the time of rubbing the concentrate lasts from 2 to 4 h.

Order status tracking

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Scarlett
Rotary tablet press RZK-25 I want to order with delivery to Berlin 07/07/2026 03:52

Roman Tsibulsky
Good day, Scarlett We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 07/07/2026 03:55

Jayden
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 07/07/2026 04:02

Roman Tsibulsky
Hello Jayden, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in York to 50 working ( not calendar) days. Action taken. 07/07/2026 04:03

Emilia
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 07/07/2026 04:12

Roman Tsibulsky
Emilia, Checking delivery status. The shipment is already in Madrid warehouse. Please arrange for pickup. 07/07/2026 04:13

Oliver
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Mariehamn ? 07/07/2026 04:22

Roman Tsibulsky
Good afternoon, Oliver! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 07/07/2026 04:22

Alexander
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 07/07/2026 04:32

Roman Tsibulsky
Hello Alexander, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Los Angeles . 07/07/2026 04:33

Henry
PU-250 flow-pack packaging machine, please advise delivery status. 07/07/2026 04:42

Roman Tsibulsky
Hello Henry, your equipment is undergoing customs clearance. Your manager Natalia will contact you as agreed 07/07/2026 04:45

James
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Gerona ? 07/07/2026 04:52

Roman Tsibulsky
Good afternoon, James! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 07/07/2026 04:52

Hazel
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 07/07/2026 05:02

Roman Tsibulsky
Hello Hazel, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 07/07/2026 05:03

Ethan
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 07/07/2026 05:12

Roman Tsibulsky
Hello Ethan, We are on time, between 12:00-14:00 a driver will contact you about unloading. 07/07/2026 05:13

Matthew
You have to pay for delivery to Perast over and above the delivery amount in the contract ? 07/07/2026 05:22

Roman Tsibulsky
Matthew, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 07/07/2026 05:23