СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

To push the pressed tablet out of the die, a force is required to overcome the friction and adhesion between the side of the tablet and the die wall. Based on the magnitude of the ejection force, additions of sliding (sliding or lubricating) agents are predicted. As an example, the results of determining the technological characteristics of rounded-shaped substances are presented. Powders with rounded particles with basic particle size more than 100 microns (Ranitidine g/hl, carbamazepine, phenazepam) have high (8-9 g/s) bulkiness, high volumetric density before and after compaction, but insignificant compressibility and small compaction coefficient.
Phenazepam has a slightly lower bulkiness value (8 g/s), probably because it contains more fines and does not contain particles larger than 250 microns, which are present in ranitidine and carbamazepine.

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Information updated : 07 / 03 / 2026
In stock
Manufacturer : 1 year for Force to push tablets out of the matrix

Model: Force to push tablets out of the matrix

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The image of the object surface topography is visually observed on the monitor screen and recorded on large-format photographic film. The principle of operation of the electron scanning microscope is as follows: a narrow beam of electrons with kinetic energy of the order of 1-25 kV falls on the sample under study. Electrons of the reflected beam (secondary electrons), released by atoms on the surface, form an image that is registered on the screen or microphotograph. In order to avoid sample damage or combustion, the sample is pre-coated with a conductive layer (usually a thin layer of gold) to prevent charging of the surface. The method of electron scanning microscopy allows to determine with high resolution the structure of the studied samples, shape and size of particles, pore size, pore size distribution, surface porosity and visualize pore geometry.

Pharmaceutical Glossary

Antifriction agents — A group of materials that have a low coefficient of friction, or materials that can reduce the coefficient of friction of other materials.

Technical specifications

This once again proves the fact that the finer the particles, the lower the friability.
The above-described technological characteristics of powdered drug substances are of paramount importance in the development of composition and technology of tablet forms, which should provide the necessary bioavailability and, accordingly, the effectiveness and safety of the drug.
Technological characteristics of powders are established quickly enough, methods of their determination are simple and do not cause difficulties, therefore these methods are now widely used in the pharmaceutical industry for mass control of all incoming drug substances.

Additional information

As a rule, pharmaceutical companies analyze the dispersibility of drug substances by such available methods as sieve analysis, microscopy, using a laser particle analyzer, etc. This allows already at the stage of selection of firms-suppliers of drug substances to exclude non-standard substances in the developed technological process and ensure high quality of domestic tablet preparations. The method of electron scanning microscopy can be used to determine such properties as surface, shape and size of particles. Stationary electron scanning microscope designed to study the topography (microgeometry) of the surface of a solid body by secondary electron emission.

Order status tracking

Roman Tsibulsky +79853643808 now online

Aiden
Good afternoon, please confirm that in the interval from 10:00-12:00 we will receive our shipment in Vienna? Contact the transportation company. 13/03/2026 22:43

Roman Tsibulsky
Hello Aiden ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Vienna in a few days. Please expect it. 13/03/2026 22:46

Layla
Tell me the NJ-120 automatic capsule machine went ? 13/03/2026 22:53

Roman Tsibulsky
Layla, good afternoon. Yes, already tomorrow until 16:30 you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 13/03/2026 22:53

Alexander
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 13/03/2026 23:03

Roman Tsibulsky
Good afternoon Alexander, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. between 16:00-18:00 we will get a reply from the manufacturer on the final time frame. 13/03/2026 23:05

Lily
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Las Vegas 13/03/2026 23:13

Roman Tsibulsky
Hello Lily, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 13/03/2026 23:15

Hannah
RZW-29 rotary tablet press in Cinque Terre. Regards, Hannah. 13/03/2026 23:23

Roman Tsibulsky
Hannah, Delivery will be made after lunch to Cinque Terre . Please have the movers ready. The weight of the equipment is heavy. 13/03/2026 23:26

Muhammad
Please advise the delivery status of the order. Desktop ampoule sealing machine RF-01 delivery to Los Angeles. Thank you. 13/03/2026 23:33

Roman Tsibulsky
Muhammad, Checked delivery status , your shipment is in transit warehouse in Shanghai. Delivery to Los Angeles is scheduled for closer to evening. Please notify us upon receipt. 13/03/2026 23:34

Lily
Remember me? There's a delivery in the Cinque Terre 13/03/2026 23:43

Roman Tsibulsky
Lily, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be In the afternoon in Cinque Terre . 13/03/2026 23:45

Wyatt
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 13/03/2026 23:53

Roman Tsibulsky
Wyatt, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 13/03/2026 23:53

Owen
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 14/03/2026 00:03

Roman Tsibulsky
Hello Owen, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in USA to 50 working ( not calendar) days. Action taken. 14/03/2026 00:06

Olivia
HX-9 plastic tube filling and sealing machine bought a month ago, arrival status in Albufeira. 14/03/2026 00:13

Roman Tsibulsky
Hello Olivia, Delivery status checked, between 12:00-14:00 is arriving at Albufeira . The driver will call you beforehand. 14/03/2026 00:15