СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

To push the pressed tablet out of the die, a force is required to overcome the friction and adhesion between the side of the tablet and the die wall. Based on the magnitude of the ejection force, additions of sliding (sliding or lubricating) agents are predicted. As an example, the results of determining the technological characteristics of rounded-shaped substances are presented. Powders with rounded particles with basic particle size more than 100 microns (Ranitidine g/hl, carbamazepine, phenazepam) have high (8-9 g/s) bulkiness, high volumetric density before and after compaction, but insignificant compressibility and small compaction coefficient.
Phenazepam has a slightly lower bulkiness value (8 g/s), probably because it contains more fines and does not contain particles larger than 250 microns, which are present in ranitidine and carbamazepine.

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Information updated : 10 / 12 / 2025
In stock
Manufacturer : 1 year for Force to push tablets out of the matrix

Model: Force to push tablets out of the matrix

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Our service and customer service

The image of the object surface topography is visually observed on the monitor screen and recorded on large-format photographic film. The principle of operation of the electron scanning microscope is as follows: a narrow beam of electrons with kinetic energy of the order of 1-25 kV falls on the sample under study. Electrons of the reflected beam (secondary electrons), released by atoms on the surface, form an image that is registered on the screen or microphotograph. In order to avoid sample damage or combustion, the sample is pre-coated with a conductive layer (usually a thin layer of gold) to prevent charging of the surface. The method of electron scanning microscopy allows to determine with high resolution the structure of the studied samples, shape and size of particles, pore size, pore size distribution, surface porosity and visualize pore geometry.

Pharmaceutical Glossary

Antifriction agents — A group of materials that have a low coefficient of friction, or materials that can reduce the coefficient of friction of other materials.

Technical specifications

This once again proves the fact that the finer the particles, the lower the friability.
The above-described technological characteristics of powdered drug substances are of paramount importance in the development of composition and technology of tablet forms, which should provide the necessary bioavailability and, accordingly, the effectiveness and safety of the drug.
Technological characteristics of powders are established quickly enough, methods of their determination are simple and do not cause difficulties, therefore these methods are now widely used in the pharmaceutical industry for mass control of all incoming drug substances.

Additional information

As a rule, pharmaceutical companies analyze the dispersibility of drug substances by such available methods as sieve analysis, microscopy, using a laser particle analyzer, etc. This allows already at the stage of selection of firms-suppliers of drug substances to exclude non-standard substances in the developed technological process and ensure high quality of domestic tablet preparations. The method of electron scanning microscopy can be used to determine such properties as surface, shape and size of particles. Stationary electron scanning microscope designed to study the topography (microgeometry) of the surface of a solid body by secondary electron emission.

Order status tracking

Roman Tsibulsky +79853643808 now online

Daniel
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 28/12/2025 18:54

Roman Tsibulsky
Hello Daniel, Transportation has advised that after lunch driver will definitely deliver the box to your address. We apologize. 28/12/2025 18:56

Eleanor
Mixer with paddle for powders CX-100 what is the exact packing size ? 28/12/2025 19:04

Roman Tsibulsky
Eleanor, Hello! Packing dimensions 1200x640x1000 mm, packing weight 250 kg. Please let me know when you receive the shipment. 28/12/2025 19:05

Dylan
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 28/12/2025 19:14

Roman Tsibulsky
Good afternoon, Dylan! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 28/12/2025 19:15

Harper
I'm waiting to get my XL-12 plastic bottle filling and capping machine to Dubrovnik, then I want to buy an automatic capsule machine model GN-28 28/12/2025 19:24

Roman Tsibulsky
Good afternoon, Harper! On the first question - the shipment will arrive in Dubrovnik as agreed. On the second question - the model GN-28 will be processed under a new contract ? Contact the office. 28/12/2025 19:27

Sebastian
We're from New Jersey, we paid for the equipment on your invoice yesterday. Has the payment been received? How long will it take to deliver to us? 28/12/2025 19:34

Roman Tsibulsky
Sebastian, hello. Payment is credited to our settlement account. Term of manufacture of your equipment by the factory 20 working days, delivery from the factory to our warehouse in the USA 1 month, delivery from the warehouse in Boston 15 calendar days. 28/12/2025 19:34

Joseph
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 28/12/2025 19:44

Roman Tsibulsky
Hello Joseph, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Denver . 28/12/2025 19:47

James
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 28/12/2025 19:54

Roman Tsibulsky
Hello James, Our manager Natalia tomorrow until 18: 30 will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Albufeira in 15 days. 28/12/2025 19:55

Leah
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Virginia Beach 28/12/2025 20:04

Roman Tsibulsky
Hello Leah, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 28/12/2025 20:04

Harper
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 28/12/2025 20:14

Roman Tsibulsky
Harper, Checking delivery status. The shipment is already in Paris warehouse. Please arrange for pickup. 28/12/2025 20:17

Ethan
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 28/12/2025 20:24

Roman Tsibulsky
Hello Ethan, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 28/12/2025 20:26