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СATALOGUE / MEDICINE MANUFACTURING FROM EXPERTS / How to develop a process for granulating powders?

How to develop a process for granulating powders?

  • Granulation of powders
  • Granulation of powders in production
  • Pelletizing in production
  • Granulation Training
  • Blister pack for tablets
  • Dedusting of tablets and capsules
  • technologist advice for pressing
  • measuring cylinder 1000 ml
  • pharmaceutical preparation
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  • hydrophobic filter
  • Production of aluminium tubes

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СATALOGUE / MEDICINE MANUFACTURING FROM EXPERTS / How to develop a process for granulating powders?

How to develop a process for granulating powders?

Here are my tips for you. Now the most important thing about a granulator’s ability to make the granules you want. Basically a granulator is a simple mechanical device that rubs moistened powder through holes in a mesh or stainless steel sheet. A granulator – Does not mix the powder – Does not moisten the powder – Does not mix the moistened powder – Does not dry the granules – Does not separate the granules into good and substandard. – Does not give 100% pellets of the same mold size, etc. Its simple function is to rub your moistened powder through the holes. To check whether the granulator is suitable for you can be easily and simply (and at the same time to practice in the technology of moistening) In a bowl pour 1 kg of powder, moisten it (the question is what exactly ????!!!!!) to such an extent that the powder in your fist when you squeeze it left an imprint in your hand (well, in general, not scattered). Strong moistening will not form granules, weak moistening will not form granules either. Strong moisturizing will leave a drying problem.

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  • Information updated : 09 / 02 / 2025
  • In stock
  • Manufacturer : 1 year for How to develop a process for granulating powders?

Model: How to develop a powder granulation process

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Our service and customer service

1) TRAINING IN PELLETIZING TECHNOLOGY.
Training on our equipment before purchase is possible. Testing of materials. We provide advice on the organization of production of granulation materials, with a full range of additional equipment and consumables.
2) COMPLETE LABORATORIES OF PHARMACEUTICAL PRODUCTION.
In USA we have a laboratory test granulator for production of pilot batches, which we provide to our clients. You can always contact us with your ideas and inquiries. Nowadays, pelletizer manufacturer can offer equipment for large scale pellet production by all methods.
3) PELLETIZER SUPPLIES.
The products are fully compliant with the new GMP requirements. The production of pelletizers is accompanied by strict quality control, verification of all documentation, well-organized after-sales service of the equipment.
4) SPARE PARTS SUPPLY
The manufacturer can also offer the granulator model according to the customer’s goals and objectives. We will provide assistance in maintenance and repair of any pelletizing equipment. Service center in USA for CIS countries.

Pharmaceutical Glossary

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Technical specifications

After evenly stirring the powder and moistening it, you get a mass ready for pelletizing. It is necessary to make a frame of wooden boards 40 cm long and wide … a kind of square and on it nail (pre-tensioned) mesh of steel wire. The thickness of the wire is not less than 0.5 mm, the size of the cell 2 mm by 2 mm. You put the moistened mass on the grid and with a plastic or steel spatula wiping movements from side to side wipe the powder through the grid. The output will be some semblance of what a granulator will mechanically do. The quality of the granules depends on the combination of substances that are moistened and the amount of this liquid in the powder mass. If you get quality pellets with this experimental variant, you can buy a pelletizer.

Additional information

There are several types of pelletizers and technologies. I have prepared a selection of three types of equipment for you. Carefully study the photos, descriptions, prices and videos of operation. Almost under the description of each model there is a video about its work.

TYPE #1. With powder humidification. Minuses of this technology Requires moistening and mixing of wet powder in a special mixer. Subsequent drying of the obtained granules and sifting them into fractions in a vibrating machine. Pros Low price, compact size, simplicity (with proper selection of technology, what and how to moisturize).

TYPE #2. In a fluidized bed. Minuses of this technology Relatively high price, small batches of loading, the time of obtaining pellets is longer. Pros. There is a possibility to receive uniformly sized round spherical pellets, there is a possibility to control their size, equipment drying pellets and the output is a finished product. There is no need to buy additional equipment.

TYPE #3. Ideal for those who do not need to lose time for moisturizing, drying, selection of technology. Minuses of this technology: High cost of equipment, low productivity, overall dimensions. Pros. Powder is granulated by squeezing between metal rollers, a plate is formed, which is crumbled into cubes of the required size. By changing the pattern of notches on the rollers you can adjust the size of the particles. No pre-treatment with powder moistening, granules in pure form.

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