СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

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СATALOGUE / DRYING OF BULK MATERIALS IN A FLUIDIZED BED / Combining spray drying and freeze drying

Combining spray drying and freeze drying

The evaporation surface and the thickness of the frozen material layer play a significant role in improving heat and mass transfer. Increasing the evaporation surface is achieved by increasing the dispersibility and specific surface area of the material. This can be accomplished by atomization and additional pulverization of the frozen product, which allows to obtain a product of high dispersibility. According to preliminary estimates, the cost of removing 1 kg of moisture by spray drying is 6 times less than freeze drying. At the same time, transportation costs are significantly lower, and the condition of the products is stable during long-term storage. However, research has shown that spray drying can only be used for microorganisms that can withstand high temperatures.

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Information updated: 28 / 09 / 2026
Available for
Production: 1 year на распылительную и сублимационную сушилки

Model: Combining spray drying and freeze drying

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Powders obtained by spray drying and combined spray and freeze drying have fundamental differences in particle shape. At the same time, the residual moisture content, surface properties of particles obtained by these two methods were similar. In both cases, the bulkiness was unsatisfactory. With the use of additives, an improvement in bulkiness was observed. In view of the above, it becomes obvious that there is a need to improve the energy efficiency of freeze dehydration technology, to develop new equipment, to create combined drying methods aimed at improving the quality of the obtained products. One of the tasks of improving the process of freeze drying (reducing the duration, energy consumption of the process) with simultaneous solution of the problems of quality of the obtained products can be solved by transition from drying in vacuum to drying at atmospheric pressure.

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Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

For most crops, however, freeze drying remains the only suitable method. Recent research by scientists has shown that spray drying and freeze drying can be combined in a single process to produce protein-rich dry powders, with the main advantage of obtaining a highly dispersed product.
The process was carried out in two stages: spraying of the solution in a metal container filled with liquid nitrogen under constant shaking; freeze drying in a Crist vacuum lyophilizer. At the same time, the quality of products dried by the combined method (degree of preservation of valuable properties, original structure, activity of ingredients) is not inferior to freeze-dried in vacuum.

Additional information

The products have better bulkiness and morphology, and there is no sintering of the top layer. The powders obtained in this way can be used for further encapsulation, pressing, epidermal administration, as well as for increasing the solubility of poorly soluble substances. Some scientists have also investigated the effect of the drying method on powder friability, which depends on a combination of different factors: size, shape, and surface properties of the particles. The comparison of spray and combined spray and freeze drying methods was carried out in terms of such indicators as: particle size and shape; moisture content, physical and chemical properties; the influence of additives and coatings on the friability of powders.

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Evelyn
Good afternoon, please confirm that in the interval from 10:00-12:00 we will receive our shipment in Brussels? Contact the transportation company. 01/10/2026 08:19

Roman Tsibulsky
Hello Evelyn ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Brussels in a few days. Please expect it. 01/10/2026 08:19

Ruby
Please inform me about the status of the order Rotary tablet press RZ-10A in Phoenix ? 01/10/2026 08:29

Roman Tsibulsky
Good afternoon, Ruby. We have contacted the carrier, delivery is scheduled the day after tomorrow. Please let us know when you receive it. Thank you. 01/10/2026 08:32

Aiden
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 01/10/2026 08:39

Roman Tsibulsky
Hello Aiden, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 01/10/2026 08:42

Samuel
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 01/10/2026 08:49

Roman Tsibulsky
Hello Samuel, We are on time, tomorrow until 15:30 a driver will contact you about unloading. 01/10/2026 08:51

Jackson
Excuse me, I have important information, please do not deliver my shipment, automatic filling and sealing machine for glass ampoules ALG-10 to Jurmala, but immediately upon arrival send it to Monte Carlo. 01/10/2026 08:59

Roman Tsibulsky
Hello Jackson, we will try to resolve this issue for you. 01/10/2026 09:00

Luna
Automatic blister packaging machine for PVC+cardboard LW-35 with delivery to Miami. We want to track the delivery status. 01/10/2026 09:09

Roman Tsibulsky
Luna, hello. The shipment has already arrived. Now it is in the warehouse of the transportation company. Your manager will contact you to clarify the time of delivery to your city. 01/10/2026 09:10

Layla
Horizontal granulator for organic fertilizers JU-80, the price is up to date ? Delivery time to Dublin? Urgent. 01/10/2026 09:19

Roman Tsibulsky
Layla, Please read carefully the description of this model in our catalog. Prices are current. Timing 1-1.5 months. 01/10/2026 09:22

Savannah
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 01/10/2026 09:29

Roman Tsibulsky
Hello Savannah, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 01/10/2026 09:30

Penelope
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Madrid, do you deliver to the terminal or to the actual address? 01/10/2026 09:39

Roman Tsibulsky
Hello Penelope, we ship all over Europe and the US including to Madrid . The price in the catalog includes any delivery our customer asks for. 01/10/2026 09:42

Ava
Remember me? There's a delivery in the Dublin 01/10/2026 09:49

Roman Tsibulsky
Ava, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be before lunch in Dublin . 01/10/2026 09:51