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The most common combinations are the combination of a wet granulator-mixer with a spheronizer and an extruder with a spheronizer. Fluidized bed pelletizing. Pellets can be produced using a rotary insert in.a fluidized bed. The powder is mixed and moistened, the solvent or binder is fed tangentially. The powder layer is driven in a circular motion by the rotor insert. Process air, which is supplied through an adjustable gap at the edges of the rotor insert, drives the powder bed in a spiral motion. Agglomerates are formed which, due to the rotation of the rotor insert, are rolled into dense pellets with a regular spherical shape. The number of rotor revolutions has a direct influence on the density and size of the pellets. Drying of the wet pellets takes place either directly in the rotor during the drying phase at an elevated supply air temperature or in a fluidized bed dryer. Pellets are produced directly and very quickly from powder with the addition of a binder or solvent. The resulting pellets or pellets have a high density (comparable to the density of pellets produced in vertical pelletizers). If necessary, high-solid content shells are obtained by coating.
Pharmaceutical Glossary
Technical specifications
The particle size distribution of the resulting pellets is within a wide range of sizes. Pelletizing by rolling is the process of giving a spherical shape to extrudate after the extrusion process or to wet pellets after the wet granulation process. The spherical shaped pellets provide good stable friability and pellets with minimal mass variation are obtained. For example, in the study of granulates of calcium biphosphate, magnesium hydroxide and sulfadimezine prepared by wet granulation followed by rolling, it was found that their bulkiness increased by 40-100%. Rolling of wet pellets or extrudate is carried out on equipment called spheronizer. The principle of operation of a spheronizer is as follows: in the first stage, the material is compacted. With the help of a rotor-transfer granulator pellets are formed, which in the second stage are rolled in the spheronizer to a spherical shape and removed from the apparatus. In the presented GEA spheronizer, the plate is covered with smooth recesses. The plate is rotating and is tightly adhered to the walls of the apparatus. In this way, pellets with a good spherical shape are formed and a good particle size distribution is achieved.
Additional information
The granulate or extrudate is rolled to a spherical shape under the action of centrifugal and frictional forces. This design of the spheronizer solves the problem of material edge breakage and the appearance of unwanted small particles. Optimization of the process is achieved by selecting the rotation cycle time, plate speed, product loading and controlling the air flow around the periphery of the rotating plate. In the Glatt spheronizer, wet pelletized products or pre-formed extrudates are fed onto a rotating disk for pelletizing. The rotation of the disk, the flow of incoming product and a jet of air supplied through a slit in the side wall create an orderly product movement in a spiral path at the vessel wall. Due to intensive rolling, the surface of the particles is smoothed to form pellets. The dust particles generated in this process are captured again by the resulting pellets directly in the process. To increase the throughput capacity of the equipment in batch operation, several spheronizers are combined in a cascade. The cascade principle is also used to produce pellets with a laminated structure. The structure of the pellets is determined by the granulation process that takes place earlier in the process chain.
Order status tracking
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Fresno. 29/12/2025 22:28
Good day Ruby, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Fresno is included in the price. 29/12/2025 22:30
Can your technician come to York? We need technologist consultation and assistance. 29/12/2025 22:38
Aurora, We have already received your email. A technician as agreed will contact you. Don't worry. 29/12/2025 22:41
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 29/12/2025 22:48
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Sebastian, this chat is only for tracking shipments. 29/12/2025 22:48
We're from New Jersey, we paid for the equipment on your invoice yesterday. Has the payment been received? How long will it take to deliver to us? 29/12/2025 22:58
Lucas, hello. Payment is credited to our settlement account. Term of manufacture of your equipment by the factory 20 working days, delivery from the factory to our warehouse in the USA 1 month, delivery from the warehouse in San Diego 15 calendar days. 29/12/2025 22:58
Good day , Electronic conveyor belt package weight detector DK-05 when will we receive in Krakow ? 29/12/2025 23:08
Hello Benjamin, your shipment is in the customs warehouse, as stipulated in the contract your manager Natalia will contact you. 29/12/2025 23:09
Rotary tablet press RZK-25 I want to order with delivery to Berlin 29/12/2025 23:18
Good day, Stella We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 29/12/2025 23:21
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled tomorrow by lunchtime to open the box and test. 29/12/2025 23:28
Mia, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 29/12/2025 23:31
For shipping to Cinque Terre do you have to pay anything extra ? 29/12/2025 23:38
Good day Benjamin, In our catalog, all prices are inclusive of shipping to the customer's door. Delivery to Cinque Terre is included. 29/12/2025 23:38
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Cinque Terre, do you deliver to the terminal or to the actual address? 29/12/2025 23:48
Hello Elijah, we ship all over Europe and the US including to Cinque Terre . The price in the catalog includes any delivery our customer asks for. 29/12/2025 23:50
HX-6 Plastic Tube Filling and Sealing Machine in Istanbul? Price delivery terms and conditions 29/12/2025 23:58
Abigail, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 29/12/2025 23:58
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- PERISTALTIC PUMPS DISPENSERS
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