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The most common combinations are the combination of a wet granulator-mixer with a spheronizer and an extruder with a spheronizer. Fluidized bed pelletizing. Pellets can be produced using a rotary insert in.a fluidized bed. The powder is mixed and moistened, the solvent or binder is fed tangentially. The powder layer is driven in a circular motion by the rotor insert. Process air, which is supplied through an adjustable gap at the edges of the rotor insert, drives the powder bed in a spiral motion. Agglomerates are formed which, due to the rotation of the rotor insert, are rolled into dense pellets with a regular spherical shape. The number of rotor revolutions has a direct influence on the density and size of the pellets. Drying of the wet pellets takes place either directly in the rotor during the drying phase at an elevated supply air temperature or in a fluidized bed dryer. Pellets are produced directly and very quickly from powder with the addition of a binder or solvent. The resulting pellets or pellets have a high density (comparable to the density of pellets produced in vertical pelletizers). If necessary, high-solid content shells are obtained by coating.
Pharmaceutical Glossary
Technical specifications
The particle size distribution of the resulting pellets is within a wide range of sizes. Pelletizing by rolling is the process of giving a spherical shape to extrudate after the extrusion process or to wet pellets after the wet granulation process. The spherical shaped pellets provide good stable friability and pellets with minimal mass variation are obtained. For example, in the study of granulates of calcium biphosphate, magnesium hydroxide and sulfadimezine prepared by wet granulation followed by rolling, it was found that their bulkiness increased by 40-100%. Rolling of wet pellets or extrudate is carried out on equipment called spheronizer. The principle of operation of a spheronizer is as follows: in the first stage, the material is compacted. With the help of a rotor-transfer granulator pellets are formed, which in the second stage are rolled in the spheronizer to a spherical shape and removed from the apparatus. In the presented GEA spheronizer, the plate is covered with smooth recesses. The plate is rotating and is tightly adhered to the walls of the apparatus. In this way, pellets with a good spherical shape are formed and a good particle size distribution is achieved.
Additional information
The granulate or extrudate is rolled to a spherical shape under the action of centrifugal and frictional forces. This design of the spheronizer solves the problem of material edge breakage and the appearance of unwanted small particles. Optimization of the process is achieved by selecting the rotation cycle time, plate speed, product loading and controlling the air flow around the periphery of the rotating plate. In the Glatt spheronizer, wet pelletized products or pre-formed extrudates are fed onto a rotating disk for pelletizing. The rotation of the disk, the flow of incoming product and a jet of air supplied through a slit in the side wall create an orderly product movement in a spiral path at the vessel wall. Due to intensive rolling, the surface of the particles is smoothed to form pellets. The dust particles generated in this process are captured again by the resulting pellets directly in the process. To increase the throughput capacity of the equipment in batch operation, several spheronizers are combined in a cascade. The cascade principle is also used to produce pellets with a laminated structure. The structure of the pellets is determined by the granulation process that takes place earlier in the process chain.
Order status tracking
Please inform me about the status of the order Rotary tablet press RZ-10A in Columbus ? 01/04/2026 06:43
Good afternoon, Matthew. We have contacted the carrier, delivery is scheduled tomorrow until 16:30. Please let us know when you receive it. Thank you. 01/04/2026 06:44
You have to pay for delivery to St. Gallen over and above the delivery amount in the contract ? 01/04/2026 06:53
Carter, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 01/04/2026 06:56
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 01/04/2026 07:03
Good day, Logan! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 01/04/2026 07:05
PU-250 flow-pack packaging machine, please advise delivery status. 01/04/2026 07:13
Hello Owen, your equipment is undergoing customs clearance. Your manager Natalia will contact you tomorrow until 16:30 01/04/2026 07:13
Mixer with paddle for powders CX-100 what is the exact packing size ? 01/04/2026 07:23
Emilia, Hello! Packing dimensions 1200x640x1000 mm, packing weight 250 kg. Please let me know when you receive the shipment. 01/04/2026 07:26
I would like to discuss the purchase of model FK-05 - capping and screw cap machine. 01/04/2026 07:33
Good day. You can call on tel. +79853643808 or to the mail specified on the site. Abigail, this chat is only for tracking shipments. 01/04/2026 07:33
Good afternoon, I am hoping tomorrow until 15:30 to get the UNIC 600A Tablet Press in Lucca ! Please comment. 01/04/2026 07:43
Good day, Alexander! Our manager has communicated with the delivery service, the equipment will be delivered to Lucca at your address. Please let us know when you receive it. 01/04/2026 07:46
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled the day after tomorrow to open the box and test. 01/04/2026 07:53
Oliver, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 01/04/2026 07:57
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 01/04/2026 08:03
Joseph, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Detroit ? Contact Natalia, she will send the contract and invoice. 01/04/2026 08:03
RZW-29 rotary tablet press in Lisbon. Regards, Scarlett. 01/04/2026 08:13
Scarlett, Delivery will be made in the morning to Lisbon . Please have the movers ready. The weight of the equipment is heavy. 01/04/2026 08:15
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- FLOW-PACK PACKAGING MACHINES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- PERISTALTIC PUMPS DISPENSERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COATING TABLETS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
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