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In reality, there are no sharp boundaries between the three stages of pressing, as the processes occurring in the second stage take place in the first and third stages, and we can only speak about the predominant role of individual processes in each of the pressing stages. Studies have established that the nature of compaction of granules and powder particles during pressing depends on their strength. As mentioned in Sect. 4.4, tablets are produced by three methods: wet granulation, dry granulation and direct pressing.
Pharmaceutical Glossary
Technical specifications
In the second stage of pressing, as the pressing pressure increases, the material is intensively compacted by filling the voids and various types of deformation, which contribute to a more compact packing of the material. The resulting deformations can be of the following types: deformation due to elasticity helps the particles to wedge into each other, which increases the contact surface; deformation due to plastic properties makes the particles change their shape and fit more tightly together; deformation determined by the brittleness of the material, characterized by the destruction of the pressed material, occurs only when the stresses occurring in the pressed material exceed the yield strength of the material.
Additional information
In this case there is a mechanical destruction of material particles into smaller ones, accompanied by a significant increase in surface energy, which creates conditions for the emergence of contacts between particles. At the second stage of pressing a compact porous body with sufficient mechanical strength is formed from the bulk material. At the third stage of pressing at high pressure values, when the mechanical strength of tablets changes insignificantly, there is possibly a volumetric compression of powder particles and granules without a noticeable increase in contact surfaces.
Order status tracking
Remember me? There's a delivery in the Porto 26/03/2025 23:57
Natalie, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be In the afternoon in Porto . 27/03/2025 00:00
Please inform me about the status of the order Rotary tablet press RZ-10A in Seattle ? 27/03/2025 00:07
Good afternoon, Isabella. We have contacted the carrier, delivery is scheduled tomorrow until 12:30. Please let us know when you receive it. Thank you. 27/03/2025 00:11
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 27/03/2025 00:17
Hello Victoria, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 27/03/2025 00:20
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Oakland 27/03/2025 00:27
Hello Luna, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 27/03/2025 00:27
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 27/03/2025 00:37
Abigail, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 27/03/2025 00:39
RZW-29 rotary tablet press in Crete. Regards, Owen. 27/03/2025 00:47
Owen, Delivery will be made tomorrow until 16:30 to Crete . Please have the movers ready. The weight of the equipment is heavy. 27/03/2025 00:49
Waiting for delivery to Split of a TR-02 hard gelatin capsule polishing machine. What about it? 27/03/2025 00:57
Hello James, on your order we inform you that tomorrow until 18: 30 the driver will contact you to clarify the time and place of unloading. 27/03/2025 00:58
Automatic blister packaging machine for PVC+cardboard LW-35 with delivery to Wichita. We want to track the delivery status. 27/03/2025 01:07
John, hello. The shipment has already arrived. Now it is in the warehouse of the transportation company. Your manager will contact you to clarify the time of delivery to your city. 27/03/2025 01:11
RZW-29 rotary tablet press in Bucharest. Regards, Matthew. 27/03/2025 01:17
Matthew, Delivery will be made after lunch to Bucharest . Please have the movers ready. The weight of the equipment is heavy. 27/03/2025 01:19
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 27/03/2025 01:27
Scarlett, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 27/03/2025 01:28
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR COATING TABLETS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- AUTOMATIC CARTONING MACHINES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- AUTOMATIC CARTONING MACHINES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR MIXING POWDERS